Results 251 to 260 of about 297,882 (348)

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

Advanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu, Huaqian Xue, Zhiyun Liu, Jiameng Rao, Lingyao Zeng, Chen Zhang, Lanjie Lei, Liyun Shi   +7 more
wiley   +1 more source

INCREASED IMPACT OF ACUTE REJECTION ON CHRONIC ALLOGRAFT FAILURE IN RECENT ERA

, 2000
Herwig‐Ulf Meier‐Kriesche, Akinlolu Ojo, J. A. Hanson, Diane M. Cibrik, Jeffrey D. Punch, A B Leichtman, Bruce Kaplan   +6 more
openalex   +1 more source

From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies

Advanced Science, EarlyView.
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen, Ran Ren, Lirong Yan, Yu Zhou, Ruokai Sun, Huicong Song, Hongfei Yan, Yongsheng Li   +7 more
wiley   +1 more source

Prediction of renal allograft chronic rejection using a model based on contrast-enhanced ultrasonography. [PDF]

Microcirculation, 2019
Yang C, Wu S, Yang P, Shang G, Qi R, Xu M, Rong R, Zhu T, He W.   +8 more
europepmc   +1 more source

HYPERCHOLESTEROLEMIA IS ASSOCIATED WITH INCREASED KIDNEY GRAFT LOSS CAUSED BY CHRONIC REJECTION IN MALE PATIENTS WITH PREVIOUS ACUTE REJECTION

, 2000
Karl Martin Wissing, Daniel Abramowicz, Nilüfer Broeders, Pierre Vereerstraeten   +3 more
openalex   +1 more source

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source

Lung transplantation: chronic rejection and stem cell depletion. [PDF]

J Thorac Dis, 2018
Lynch TJ, Ahlers BA, Parekh KR.
europepmc   +1 more source

AN ASSOCIATION BETWEEN CYTOMEGALOVIRUS INFECTION AND CHRONIC REJECTION AFTER LIVER TRANSPLANTATION

, 2000
Paul C. Evans, Arvinder S. Soin, T. G. Wreghitt, Clare Taylor, D. G. D. Wight, Graeme Alexander   +5 more
openalex   +1 more source

Shear Stress Targeted Delivery of Nitroglycerin to Brain Collaterals Improves Ischaemic Stroke Outcome

Advanced Science, EarlyView.
Shear‐activated nanoparticles carrying nitroglycerin selectively target high‐shear stress collateral vessels during ischaemic stroke, enhancing blood flow to at‐risk brain without systemic side effects. This novel approach significantly improves outcomes in animal models, outperforming conventional nitroglycerin delivery.
Magdalena Litman, Sara Azarpeykan, Rebecca J Hood, Kristy Martin, Debbie Pepperall, Daniel Omileke, Fern Williams, Oktay Uzun, Deen Bhatta, Yuen K Yong, Alex Chan, Nicholas Hough, Sarah Johnson, Pablo Garcia Bermejo, Ferdinand Miteff, Carlos Garcia Esperon, Yvonne Couch, Alastair M Buchan, Neil J Spratt, Netanel Korin, Donald E Ingber, Daniel J Beard   +21 more
wiley   +1 more source

SDZ-RAD PREVENTS MANIFESTATION OF CHRONIC REJECTION IN RAT RENAL ALLOGRAFTS

, 2000
Ondrej Viklick, Hequn Zou, Veronika Müller, J Lácha, A. Szab�, Uwe Heemann   +5 more
openalex   +1 more source