Results 61 to 70 of about 297,882 (348)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Biomarkers in solid organ transplantation: establishing personalized transplantation medicine. [PDF]

, 2011
Technological advances in molecular and in silico research have enabled significant progress towards personalized transplantation medicine. It is now possible to conduct comprehensive biomarker development studies of transplant organ pathologies ...
Khatri, Purvesh, Roedder, Silke, Sarwal, Minnie M, Vitalone, Matthew   +3 more
core   +3 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Current status of xenotransplantation research and the strategies for preventing xenograft rejection

Frontiers in Immunology, 2022
Transplantation is often the last resort for end-stage organ failures, e.g., kidney, liver, heart, lung, and pancreas. The shortage of donor organs is the main limiting factor for successful transplantation in humans.
Qiao Zhou, Qiao Zhou, Qiao Zhou, Ting Li, Kaiwen Wang, Qi Zhang, Zhuowen Geng, Shaoping Deng, Shaoping Deng, Shaoping Deng, Chunming Cheng, Yi Wang   +11 more
doaj   +1 more source

Cytokines and graft function in heart transplant recipients [PDF]

, 2002
Allo-antigen dependent and independent factors early after heart transplantation lead to a response-to-injury mechanism that may determine later outcome in terms of acute rejection, chronic rejection, graft dysfunction, and mortality. 13·24'30'53 The aim
Groot-Kruseman, H.A. de
core  

What have we learned about primary liver transplantation under tacrolimus immunosuppression? - Long-term follow-up of the first 1000 patients [PDF]

, 1999
Objective: To summarize the long-term efficacy and safety of tacrolimus in orthotopic liver transplant (OLT) recipients, as well as to examine the factors that influence long-term morbidity and mortality rates. Background: Tacrolimus (FK506, Prograf) was
Abu-Elmagd, K, Fung, J, Jain, A, Kashyap, R, Reyes, J, Rohal, S, Starzl, T   +6 more
core   +2 more sources

Designing and Delivering Effective Faculty Development With the Adult Learner in Mind

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT University faculty are busy professionals tasked with many different responsibilities. While they certainly care about student success, their expertise is generally discipline‐specific and strategies for effective and engaging teaching are developed in the classroom along the way.
Nancy V. Winfrey
wiley   +1 more source

Analysis of chronic rejection and obliterative arteriopathy: Possible contributions of donor antigen-presenting cells and lymphatic disruption [PDF]

, 1997
Sequential analysis of changes that lead to chronic rejection was undertaken in an animal model of chronic rejection and obliterative arteriopathy. Brown Norway rats are pretreated with a Lewis bone marrow infusion or a Lewis orthotopic liver allograft ...
Demetris, AJ, Duquesnoy, RJ, Fling, JJ, Galvao, FHF, Murase, N, Pham, S, Richert, C, Saad, R, Starzl, TE, Ye, Q, Zeevi, A   +10 more
core   +1 more source

Intrahepatic bile duct strictures after human orthotopic liver transplantation - Recurrence of primary sclerosing cholangitis or unusual presentation of allograft rejection? [PDF]

, 1988
One of 55 patients transplanted for sclerosing cholangitis during the cyclosporin-steroid era (March 1980-June 1986) developed intrahepatic biliary strictures in the absence of allograft rejection within the 1st year posttransplantation.
A. C. Stieber, A. J. Demetris, AJ Demetris, B Portmann, C. O. Esquivel, J Lerut, J Neuberger, J. Lerut, J. W. Marsh, JW Marsh, KA Porter, R. D. Gordon, RH Fennell, S Iwatsuki, S. Iwatsuki, T. E. Starzl, TE Starzl   +16 more
core   +1 more source

Where, how, and how much? A multicenter cohort study of the relationship between lupus decision aid modality, place of administration, interruption and viewing completeness and patient‐reported outcomes

Arthritis Care &Research, Accepted Article.
Objective We assessed whether shared decision‐making (SDM), and patient acceptability, feasibility, and overall satisfaction with a computerized patient decision aid (PtDA) for patients with systemic lupus erythematosus (SLE), differs by PtDA setting, modality, and the viewing experience.
Jasvinder A. Singh, Mark Beasley, Larry R. Hearld, for the Implementing DEcision‐Aid for Lupus in clinics (IDEAL) Consortium   +3 more
wiley   +1 more source