Results 61 to 70 of about 3,296,949 (379)

KIR and their HLA Class I ligands: Two more pieces towards completing the puzzle of chronic rejection and graft loss in kidney transplantation

PLoS ONE, 2017
Background Kidney transplantation is a life-saving treatment for patients with end-stage renal disease. However, despite progress in surgical techniques and patient management, immunological rejection continues to have a negative impact on graft function
R. Littera, G. Piredda, Davide Argiolas, S. Lai, E. Congeddu, Paola Ragatzu, M. Melis, E. Carta, M. B. Michittu, D. Valentini, L. Cappai, R. Porcella, F. Alba, M. Serra, V. Loi, R. Maddi, S. Orrù, G. La Nasa, G. Caocci, R. Cusano, M. Arras, M. Frongia, A. Pani, C. Carcassi   +23 more
semanticscholar   +1 more source

A histometric analysis of chronically rejected human liver allografts: Insights into the mechanisms of bile duct loss: Direct immunologic and ischemic factors [PDF]

, 1989
Conspicuous pathologic features of chronic liver allograft rejection include bile duct loss and chronic obliterative arteriopathy. A quantitative histometric analysis was performed to document the extent of bile duct loss, the size of the “vanished ...
Belle, S, Demetris, AJ, Oguma, S, Starzl, TE   +3 more
core   +1 more source

B-cell-mediated strategies to fight chronic allograft rejection

Frontiers in Immunology, 2013
Solid organs have been transplanted for decades. Since the improvement in graft selection and in medical and surgical procedures, the likelihood of graft function after one year is now close to 90%.
Ali H Dalloul
doaj   +1 more source

Current status of xenotransplantation research and the strategies for preventing xenograft rejection

Frontiers in Immunology, 2022
Transplantation is often the last resort for end-stage organ failures, e.g., kidney, liver, heart, lung, and pancreas. The shortage of donor organs is the main limiting factor for successful transplantation in humans.
Qiao Zhou, Qiao Zhou, Qiao Zhou, Ting Li, Kaiwen Wang, Qi Zhang, Zhuowen Geng, Shaoping Deng, Shaoping Deng, Shaoping Deng, Chunming Cheng, Yi Wang   +11 more
doaj   +1 more source

Cause and timing of first allograft failure in orthotopic liver transplantation: A study of 177 consecutive patients [PDF]

, 1991
The cause and timing of first liver allograft failure was evaluated in 177 patients who underwent a second liver transplant between January 1984 and December 1988.
Busuttil, Carithers, Demetris, Demetris, Klintmalm, Krom, Kusne, Lerut, Maddrey, Polson, Ringe, Scharschmidt, Shaw, Starzl, Starzl, Starzl, Starzl, Starzl, Tzakis, van Thiel, Wozney, Yanaga, Yanaga   +22 more
core   +1 more source

The influence of HLA matching on cytomegalovirus hepatitis and chronic rejection after liver transplantation [PDF]

, 1993
Previous findings in liver transplantation patients have raised the concept that HLA plays a dualistic role. HLA matching will reduce rejection but may augment MHC restricted cellular immune mechanisms of liver allograft injury. To evaluate this concept,
Demetris, AJ, Duquesnoy, RJ, Kramer, D, Kusne, S, Linden, P, Martin, M, Mañez, R, Starzl, TE, Van Thiel, DH, White, LT   +9 more
core   +1 more source

Graft‐Infiltrating Macrophages Adopt an M2 Phenotype and Are Inhibited by Purinergic Receptor P2X7 Antagonist in Chronic Rejection

American Journal of Transplantation, 2016
Macrophages exhibit diverse phenotypes and functions; they are also a major cell type infiltrating chronically rejected allografts. The exact phenotypes and roles of macrophages in chronic graft loss remain poorly defined. In the present study, we used a
Chenglin Wu, Yue Zhao, Xiang Xiao, Yihui Fan, M. Kloc, W. Liu, R. Ghobrial, Peixiang Lan, Xiaoshun He, Xian Chang Li   +9 more
semanticscholar   +1 more source

Baboon-to-human liver transplantation [PDF]

, 1993
Our ability to control both the cellular and humoral components of xenograft rejection in laboratory experiments, together with an organ shortage that has placed limits on clinical transplantation services, prompted us to undertake a liver ...
A Tzakis, A Zeevi, A Zeevi, A.J Demetris, A.J Demetris, Alper, Asonuma, Bailey, Barnard, Cano, Crawford, Essex, Francavilla, H Doyle, Hasan, Hitchcock, I.R Marino, Iwaki, J Fung, Jacobson, Karpas, Kelly, M Michaels, M Trucco, M Trucco, Moran, Porter, S Kusne, S Kusne, S Todo, Starzl, Starzl, Starzl, Starzl, Starzl, T.E Starzl, Takaya, Todo, Tzakis, V Warty, V Warty, W.A Rudert, W.A Rudert, Wolpl   +43 more
core   +1 more source

Differentiation of acute versus chronic skin rejection in a rodent model of vascularized composite allotransplantation

Frontiers in Immunology
BackgroundVascularized composite allografts (VCA) have evolved to be a potential option in complex reconstructive surgery. However, managing acute and chronic allograft rejection remains challenging.
Julia Thomé, Maike Lind, Maxime Schmitt, Laura Schneider, Jurij Kiefer, Jurij Kiefer, Rebecca Schäfer, Emma Freise, Thierry Christmann, Sheena Kreuzaler, Branislav Kollár, Steffen U. Eisenhardt   +11 more
doaj   +1 more source

Intestinal transplantation in composite visceral grafts or alone [PDF]

, 1992
Under FK 506-based immunosuppression, the entire cadaver small bowel except for a few proximal and distal centimeters was translated to 17 randomly matched patients, of whom two had antigraft cytotoxic antibodies (positive cross-match).
Abu-Elmagd, K, Busuttil, RW, Casavilla, A, Demetris, AJ, Fung, JJ, Nakamura, K, Nour, BM, Rapaport, FT, Reyes, J, Selby, R, Shaw, BW, Starzl, TE, Thompson, JC, Todo, S, Tzakis, AG, Van Thiel, DH, Vasconez, LO, Wright, H   +17 more
core   +1 more source