Results 71 to 80 of about 3,305,589 (380)

Chronic transplant rejection

Kidney International, 1994
A 30-year-old woman was admitted to the University of Minnesota Hospital to receive a second cadaveric renal transplant. Eighteen years earlier, she had received her first cadavenc renal transplant for renal failure due to chronic glomerulonephritis.
openaire   +2 more sources

Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants

Nature Communications, 2019
Current doctrine is that microvascular inflammation (MVI) triggered by a transplant -recipient antibody response against alloantigens (antibody-mediated rejection) is the main cause of graft failure.
A. Koenig, Chien-Chia Chen, A. Marçais, T. Barba, V. Mathias, A. Sicard, M. Rabeyrin, M. Racapé, Jean-Paul Duong-Van-Huyen, P. Bruneval, A. Loupy, S. Dussurgey, S. Ducreux, V. Meas-Yedid, Jean-Christophe Olivo-Marin, H. Paidassi, R. Guillemain, J. Taupin, J. Callemeyn, E. Morelon, A. Nicoletti, B. Charreau, V. Dubois, M. Naesens, T. Walzer, T. Defrance, O. Thaunat   +26 more
semanticscholar   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

NK Cells: Not Just Followers But Also Initiators of Chronic Vascular Rejection

Transplant International
Chronic graft rejection represents a significant threat to long-term graft survival. Early diagnosis, understanding of the immunological mechanisms and appropriate therapeutic management are essential to improve graft survival and quality of life for ...
Mathilde Chambon, Alice Koenig, Alice Koenig, Alice Koenig   +3 more
doaj   +1 more source

Donor-But Not Recipient-Derived Cells Produce Collagen-1 in Chronically Rejected Cardiac Allografts

Frontiers in Immunology, 2022
Fibrosis is a prominent feature of chronic allograft rejection, caused by an excessive production of matrix proteins, including collagen-1. Several cell types produce collagen-1, including mesenchymal fibroblasts and cells of hematopoietic origin.
Saidou Balam, Simone Buchtler, Frederike Winter, Frederike Winter, Kathrin Schmidbauer, Sophia Neumayer, Yvonne Talke, Kerstin Renner, Edward K. Geissler, Matthias Mack, Matthias Mack   +10 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Analysis of chronic rejection and obliterative arteriopathy: Possible contributions of donor antigen-presenting cells and lymphatic disruption [PDF]

, 1997
Sequential analysis of changes that lead to chronic rejection was undertaken in an animal model of chronic rejection and obliterative arteriopathy. Brown Norway rats are pretreated with a Lewis bone marrow infusion or a Lewis orthotopic liver allograft ...
Demetris, AJ, Duquesnoy, RJ, Fling, JJ, Galvao, FHF, Murase, N, Pham, S, Richert, C, Saad, R, Starzl, TE, Ye, Q, Zeevi, A   +10 more
core   +1 more source

Vendor‐specific microbiome controls both acute and chronic murine lung allograft rejection by altering CD4+Foxp3+ regulatory T cell levels

American Journal of Transplantation, 2019
Despite standardized postoperative care, some lung transplant patients suffer multiple episodes of acute and chronic rejection while others avoid graft problems for reasons that are poorly understood.
Yizhan Guo, Qing Wang, Dongge Li, O. Onyema, Z. Mei, A. Manafi, A. Banerjee, B. Mahgoub, M. Stoler, T. Barker, D. Wilkes, A. Gelman, D. Kreisel, A. Krupnick   +13 more
semanticscholar   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Cytokines and graft function in heart transplant recipients [PDF]

, 2002
Allo-antigen dependent and independent factors early after heart transplantation lead to a response-to-injury mechanism that may determine later outcome in terms of acute rejection, chronic rejection, graft dysfunction, and mortality. 13·24'30'53 The aim
Groot-Kruseman, H.A. de
core