Results 81 to 90 of about 3,189 (213)

Prevalence of Sleep Related Breathing Disorders (SRBD) and the Assessment of Quality of Sleep Among Patients with Chronic Obstructive Pulmonary Disease (COPD): An Analytical Cross-Sectional Study

National Board of Examinations Journal of Medical Sciences
Background: Sleep disturbances are common in chronic obstructive pulmonary disease (COPD) and may result from sleep-related breathing disorders (SRBD), nocturnal hypoxemia, and ventilatory insufficiency.
K. Rajarajan, V. Saravanan
doaj   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Practices of high-flow nasal therapy in acute and chronic respiratory failure: the Hi-Flow Survey

BMJ Open Respiratory Research
Background High-flow nasal therapy (HFNT) is a widely used non-invasive respiratory support technique, but data on its clinical application remain limited. This study aimed to assess clinicians’ self-reported practices, perceptions and barriers regarding
Maxime Patout, Stefano Nava, Annalisa Carlucci, Begum Ergan, Andrea Cortegiani, Christian Karagiannidis, Ignacio Martin-Loeches, Claudia Crimi, Alberto Noto, Joao Carlos Winck, Cesare Gregoretti, Deniz Inal-Ince, Frits M E M E Franssen, Christoph Fisser, Ana Cysneiros, Marieke Duiverman   +15 more
doaj   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Noninvasive respiratory support in the emergency department: Controversies and state‐of‐the‐art recommendations

Journal of the American College of Emergency Physicians Open
Acute respiratory failure is a common reason for emergency department visits and hospital admissions. Diverse underlying physiologic abnormalities lead to unique aspects about the most common causes of acute respiratory failure: acute decompensated heart
Jarrod M. Mosier, Mark Tidswell, Henry E. Wang   +2 more
doaj   +1 more source

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

Advanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini, Margalida Campaner Socias, Andreas Dimopoulos, Lorenza Rinvenuto, Enrico Pozzo, Diana Stalkopf, Angelo Serafini, Sara Morri, Ashley Wang, Rita La Rovere, Yoke Chin Chai, Sveva Bollini, Geert Bultynck, H. Llewelyn Roderick, Ioannis Papantoniou, Maurilio Sampaolesi   +15 more
wiley   +1 more source

Anesthesia experience in an adult Silver-Russell syndrome: a case report

JA Clinical Reports
Background There are no reports of anesthesia use in adult patients with Silver-Russell syndrome (SRS). Here, we report our experience with anesthesia in an adult patient with SRS complicated by chronic respiratory failure.
Akinobu Hibino, Ayaka Hibino, Yoshinori Kamiya   +2 more
doaj   +1 more source

Alpha1-antitrypsin protects the intestine from ischemia-reperfusion injury in a rat intestinal clamping model

Intestinal Failure
Background: Ischemia-reperfusion injury (IRI) remains a significant hurdle when blood flow is restored to ischemic tissue. Alpha1-antitrypsin (AAT), a serine protease inhibitor, has demonstrated strong anti-inflammatory properties, including inhibition ...
Antoine Dubois, Mathias Clarysse, Ricard Farré, Tine Wylin, Veerle Heetfeld, Emilio Canovai, Tim Vanuytsel, Gert De Hertogh, Jacques Pirenne, Laurens J. Ceulemans   +9 more
doaj   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source