Results 111 to 120 of about 84,576 (334)

Safety of Baricitinib for the Treatment of Atopic Dermatitis in Adults Over a Median of 1.6 and up to 4.6 Years Treatment: Final Integrated Analysis of Eight Clinical Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Baricitinib is a selective Janus kinase (JAK)1/JAK2 inhibitor approved in more than 70 countries for the treatment of moderate‐to‐severe atopic dermatitis (AD) in adults, and in over 30 countries for adolescents and children from age 2 years with moderate‐to‐severe AD, who are candidates for systemic therapy.
Antonio Costanzo, Antonio Torrelo, Eric L. Simpson, Marjolein De Bruin‐Weller, Diamant Thaçi, Norito Katoh, Silvia Sabatino, Andrew Buchanan, Kasia Morawska, Samuel Ogwu, Karen Denning, Jonathan I. Silverberg   +11 more
wiley   +1 more source

Hormone replacement therapy [PDF]

, 2012
Martha Hickey, Jane Elliott, Sonia Louise ...
Davison, S., Elliott, C., Hickey, M.
core   +2 more sources

A case of chronic thromboembolic pulmonary hypertension

Italian Journal of Medicine, 2020
Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially fatal complication of pulmonary embolism (PE). Organized thrombus in the pulmonary artery causes a chronic obstruction, leading to a vascular system remodeling, an increase of pulmonary vascular resistance and a chronic pulmonary hypertension.
Lucio Brugioni, Eleonora Mazzali, Chiara Catena, Francesca Mori, Francesco Benatti, Francesca De Niedehausern, Daniela Vivoli, Andrea Borsatti, Beatrice Aramini, Elisa Romagnoli   +9 more
openaire   +4 more sources

Pulmonary Transit Time Can Be Accurately Quantified From Non‐Arterial Input Function Series in First‐Pass Cardiac Perfusion MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Previous studies suggested that arterial‐input‐function (AIF) images are necessary to avoid signal saturation for pulmonary transit time (PTT) measurements. This study challenges that notion by investigating whether PTT can be accurately measured using blood pool signals from myocardial enhancement (non‐AIF) images during resting first‐
Mingyue Zhao, Lexiaozi Fan, Kyungpyo Hong, Benjamin H. Freed, Jacqueline Urban, Kelvin Chow, Li‐Yueh Hsu, Daniel C. Lee, Daniel Kim   +8 more
wiley   +1 more source

Balloon Pulmonary Angioplasty for the Treatment of Chronic Thromboembolic Pulmonary Hypertension

Methodist DeBakey Cardiovascular Journal
Chronic thromboembolic pulmonary hypertension is a rare form of pulmonary hypertension in patients who have evidence of chronic thromboembolic occlusion of the pulmonary vasculature.
Lauren N. Carlozzi, C. Huie Lin, Zachary L. Steinberg   +2 more
doaj   +1 more source

A pilot cohort study assessing the feasibility of complete revascularization with balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension.

PLoS ONE, 2021
Balloon pulmonary angioplasty improves prognosis by alleviating pulmonary hypertension in patients with chronic thromboembolic pulmonary hypertension, even with incomplete revascularization.
Shinya Fujii, Shinya Nagayoshi, Kazuo Ogawa, Makoto Muto, Toshikazu D Tanaka, Kosuke Minai, Makoto Kawai, Michihiro Yoshimura   +7 more
doaj   +1 more source

Demographics and Outcomes of Pulmonary Hypertension Patients in United States Emergency Departments [PDF]

, 2020
Introduction: Pulmonary hypertension (PH) is a common, yet under-diagnosed, contributor to morbidity and mortality. Our objective was to characterize the prevalence of PH among adult patients presenting to United States (US) emergency departments (ED ...
Camargo Jr., Carlos A., Faridi, M. Kamal, Wilcox, Susan R.   +2 more
core  

Modified Medical Research Council scale vs Baseline Dyspnea Index to evaluate dyspnea in chronic obstructive pulmonary disease [PDF]

, 2015
International audienceBackground: Assessment of dyspnea in COPD patients relies in clinical practice on the modified Medical Research Council (mMRC) scale, whereas the Baseline Dyspnea Index (BDI) is mainly used in clinical trials. Little is known on the
Caillaud, Denis, Chanez, Pascal, Deslée, Gaetan, Paillasseur, Jean-Louis, Perez, Thierry, Roche, Nicolas, Régis Burgel, Pierre   +6 more
core   +4 more sources

Pulmonary thrombo-endarterectomy for chronic thromboembolic pulmonary artery hypertension [PDF]

, 2021
Sofia Martìn Suàrez, Gregorio Gliozzi, Antonio Loforte, Fabio Niro, Mariafrancesca Fiorentino, Giulio Giovanni Cavalli, Massimiliano Palazzini, Francesco Saia, Niccolò Antonino Barbera, Marco La Monaca, Nazzareno Galiè, Davide Pacini   +11 more
openalex   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates, Michael Zientek, Kunal S. Taskar, Wen Lin, Tycho Heimbach, Stefan Willmann, Jessica Rehmel, Neil Parrott, Michael Hanley, Justine Badee, Yuan Chen, Susan Cole, Loeckie De Zwart, Sebastian Haertter, Rongrong Jiang, Masakatsu Kotsuma, Guiqing Liang, Yu‐Wei Lin, Jing Liu, Ying Ou, Juliane Rascher, Naveed A. Shaik, Jan Wahlstrom, Xiaofeng Wang, Guangqing Xiao, Ka Lai Yee, S. Y. Amy Cheung   +26 more
wiley   +1 more source