Results 181 to 190 of about 408,452 (313)

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Evaluation of Acute and Sub-Chronic Toxicity of Lactobacillus rhamnosus GG in Sprague-Dawley Rats. [PDF]

Adv Biomed Res
Vaishnavi VVK, Banik U, Sabesan GS, Adhikary AK, Parasuraman S.   +4 more
europepmc   +1 more source

Determination of the Acute and Chronic Toxicity of Sulfate from the Sulfur Autotrophic Denitrification Process to Juvenile Zebrafish (Danio rerio). [PDF]

ACS Omega, 2022
Cao G, Zhao J, Zhao G, Wan D, Wu Z, Li R, He Q.   +6 more
europepmc   +1 more source

Cardiovascular toxicity in patients with chronic myeloid leukemia treated with second‐generation tyrosine kinase inhibitors in the real‐life practice: Identification of risk factors and the role of prophylaxis

, 2018
Giovanni Caocci, Olga Mulas, Mario Annunziata, Luigiana Luciano, Massimiliano Bonifacio, Ester Orlandi, Patrizia Pregno, Sara Galimberti, Antonella Russo Rossi, Elisabetta Abruzzese, Alessandra Iurlo, Bruno Martino, Nicola Sgherza, Gianni Binotto, Fausto Castagnetti, Antonella Gozzini, Claudio Fozza, Monica Bocchia, Anna Sicuranza, Fabio Stagno, Fabio Efficace, Emilio Usala, F. De Gregorio, Luigi Scaffidi, Chiara Elena, Francesca Pirillo, Claudia Baratè, Malgorzata Monika Trawinska, Daniele Cattaneo, Claudia Labate, Gabriele Gugliotta, Matteo Molica, Giorgina Specchia, Giorgio La Nasa, Robin Foà, Massimo Breccia   +35 more
openalex   +2 more sources

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Preclinic evaluation of the safety of potential anticovid-19 phytomedicine: SAYE PLUS impacts on Wistar rat biochemical and histopathological parameters in sub-chronic toxicity study. [PDF]

BMC Pharmacol Toxicol
Ouédraogo J, Ilboudo S, Ouédraogo GG, Somda GD, Bonogo B, Dakuyo V, Ouédraogo S, Boly R, Nitiéma M, Magnini DR, Semdé R, Ouédraogo S.   +11 more
europepmc   +1 more source

TOXIC EFFECTS OF CADMIUM, BECAUSE OF CHRONIC EXPOSURE ON REPRODUCTION PARAMETERS OF CAVIA PORCELLUS FEMALES

, 2013
Albana Munga, Dashamir Xhaxhiu, Dorjana Beqiraj, Jani Mavromatı   +3 more
openalex   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

<i>Stevia rebaudiana</i> extract (main components: chlorogenic acid and its analogues) as a new safe feed additive: evaluation of acute toxicity, sub chronic toxicity, genotoxicity, and teratogenicity. [PDF]

Front Vet Sci
Li Y, Zhu L, He D, Fang L, Li Y, Tang S.
europepmc   +1 more source

Lead Toxicity Resulting from Chronic Ingestion of Opium

, 2009
Mohammad Jalili, Reza Azizkhani
openalex   +1 more source