Results 31 to 40 of about 737,090 (311)

Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]

, 2014
Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
core   +3 more sources

Organophosphorus flame retardants – Toxicity and influence on human health

Medycyna Pracy, 2015
Organophosphorus flame retardants (flame retardants, FRs) have been used for several decades in many industries, including the production of dyes, varnishes, adhesives, synthetic resins, polyvinyl chloride, hydraulic fluids, plastics and textiles.
Elżbieta Bruchajzer, Barbara Frydrych, Jadwiga Anna Szymańska   +2 more
doaj   +1 more source

Theoretical Calculation on the Reaction Mechanisms, Kinetics and Toxicity of Acetaminophen Degradation Initiated by Hydroxyl and Sulfate Radicals in the Aqueous Phase

Toxics, 2021
The •OH and SO4•− play a vital role on degrading pharmaceutical contaminants in water. In this paper, theoretical calculations have been used to discuss the degradation mechanisms, kinetics and ecotoxicity of acetaminophen (AAP) initiated by •OH and SO4•−
Mengmeng Xu, Junfang Yao, Simei Sun, Suding Yan, Jingyu Sun   +4 more
doaj   +1 more source

Durian fruit pulp extract enhances intracellular glutathione levels, mitigating oxidative stress and inflammation for neuroprotection

Scientific Reports
Durian (Durio zibethinus L.) fruit pulp is a rich source of γ-glutamylcysteine (γ-EC), a direct precursor to the antioxidant glutathione (GSH). This study elucidated the in vitro neuroprotective potential of unripe durian fruit pulp extract (UDE) against
Gholamreza Khaksar, Su Lwin Lwin Myint, Hasriadi, Pasarapa Towiwat, Supaart Sirikantaramas, Ratchanee Rodsiri   +5 more
doaj   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

Risk Assessment of Shellfish Toxins

Toxins, 2013
Complex secondary metabolites, some of which are highly toxic to mammals, are produced by many marine organisms. Some of these organisms are important food sources for marine animals and, when ingested, the toxins that they produce may be absorbed and ...
Rex Munday, John Reeve
doaj   +1 more source

Study of acute and chronic toxicity of homeopathic syrup Stodal

Фармакокинетика и Фармакодинамика, 2020
The study of acute and chronic toxicity of the homeopathic preparation syrup Stodal, produced by the Laboratory of Boiron, France, widely used in medical practice as an effective antitussive agent.
S. V. Alekseeva, A. V. Sorokina, V. V. Zabrodina, I. A. Miroshkina, A. S. Lapitskaya   +4 more
doaj   +1 more source

The Chronic and Acute Toxicity of Traditional Medicines Containing Terminalia chebula

Journal of Pharmacopuncture, 2023
Objectives: Terminalia chebula, the main ingredient of Altan Arur 5, has been used for many years in traditional medicine. This medicine is more effective than other drugs and is used to treat chronic gastritis and gastrointestinal disorders such as ...
ARONGQIQIGE, Gerelmaa Enebish, Wang Song, Wei Cheng Xi, Anuujin Gantumur, Oyunbaatar Altanbayar, Hirofumi Shimomura, Battogtokh Chimeddorj, Batnairamdal Chuluun, Avarzed Amgalanbaatar   +9 more
doaj   +1 more source

A Case of Bowen’s Disease and Small-Cell Lung Carcinoma: Long-Term Consequences of Chronic Arsenic Exposure in Chinese Traditional Medicine [PDF]

, 2004
Chronic arsenic toxicity occurs primarily through inadvertent ingestion of contaminated water and food or occupational exposure, but it can also occur through medicinal ingestion.
Castren K, Gwyn Bebb, Hutchison J, Jaeger AB, Linda Lee, Mazumder DN, Tay CH, Tseng WP, Wong ST   +8 more
core   +2 more sources

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source