Results 61 to 70 of about 88,282 (266)

Assessing Chronological Aging in Saccharomyces cerevisiae [PDF]

, 2012
Saccharomyces cerevisiae is one of the most studied model organisms for the identification of genes and mechanisms that affect aging. The chronological lifespan (CLS) assay, which monitors the survival of a non-dividing population, is one of the two methods to study aging in yeast.
Jia, Hu, Min, Wei, Mario G, Mirisola, Valter D, Longo   +3 more
openaire   +2 more sources

Accurately Deciphering Tissue Heterogeneity From Spatial Multi‐Modal and Multi‐Omics With STransformer

Advanced Science, EarlyView.
STransformer is a unified deep learning framework designed to seamlessly accommodate a comprehensive landscape of spatial data. By simultaneously capturing short‐range cellular interactions and tissue‐wide semantic patterns, it extracts robust representations to accurately dissect complex tissue heterogeneity.
Xingyi Li, Jialuo Xu, Gaoyuan Du, Xiangting Jia, Dongmin Zhao, Chunyan Zhou, Kexin Xiao, Jia Gu, Junnan Zhu, Xuequn Shang   +9 more
wiley   +1 more source

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

“How old do you feel?” Subjective age as a tool to enhance communication in primary care: a pilot observational study

BMC Primary Care
Background Subjective age has been linked to health outcomes, including functional decline and increased mortality risk. However, its utility in primary care settings remains underexplored.
Robert D. Hoffman, Galia Zacay, Joseph Azuri, Tal Hakmon Aronson, Lilach Eyal Waldman, Tanju Yilmazer, Limor Adler   +6 more
doaj   +1 more source

Dental age estimation using Willems method: A digital orthopantomographic study

Contemporary Clinical Dentistry, 2014
In recent years, age estimation has become increasingly important in living people for a variety of reasons, including identifying criminal and legal responsibility, and for many other social events such as a birth certificate, marriage, beginning a job,
Rezwana Begum Mohammed, P V Krishnamraju, P S Prasanth, Praveen Sanghvi, M Asha Lata Reddy, S Jyotsna   +5 more
doaj   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

Advanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi, Xinmei Li, Yufan Hao, Qiaoyu Wu, Yuji Yu, Siyu Li, Nuo Xu, Yi‐Hsuan Wu, Eunhye Lee, Chi Chang, Emily Hu, Ying Lu, Elizabeth Delzell, Ann W. Hsing, Shankuan Zhu   +14 more
wiley   +1 more source

Radiographic evaluation of dental age maturity in 3–17-years-old saudi children as an indicator of chronological age

Journal of Orthodontic Science, 2017
Objective: This study was aimed to evaluate the dental age in Saudi children from panoramic radiographs using the Demirjian method to estimate their chronological age.
Ayman A Al-Dharrab, Fahad F Al-Sulaimani, Mohamed S Bamashmous, Hosam A Baeshen, Khalid H Zawawi   +4 more
doaj   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

Advanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo, Jinglei Wang, Xin Wang, Han Feng, Yize Zhao, Fadong Li, Shaobin Wei, Le Zhou, Zixu Zhao, Songjie Chen, Xiangyi Kong, Jue Wang, Liu He, Shijun Xia, Xin Li, Junmeng Zhang, Xiaoxia Liu, Xueyuan Guo, Ning Zhou, Songnan Li, Chenxi Jiang, Ribo Tang, Caihua Sang, Deyong Long, Xin Du, Jianzeng Dong, Wenwu Zhu, Changsheng Ma   +27 more
wiley   +1 more source

Demirjian’s and Cameriere’s Methods for the Assessment of Dental Age Estimation in Children from a Southern Brazilian City

Diagnostics
The chronological age estimation of living individuals is a crucial part of forensic practice and clinical practice, such as in orthodontic treatment.
Julia Carelli, Gabriela Sabrina da Silva, Mariana Vegini Gomes, Thais Vilalba, Flares Baratto-Filho, João Armando Brancher, Svenja Beisel-Memmert, Christian Kirschneck, Celia Maria Condeixa de França Lopes, Alexandre Moro, Erika Calvano Küchler   +10 more
doaj   +1 more source