Results 61 to 70 of about 447,031 (304)

Frailty in Glioblastoma Is Independent From Chronological Age

open access: yesFrontiers in Neurology, 2021
Objective: Treatment of glioblastoma in elderly patients is particularly challenging due to their general condition and comorbidities. Treatment decisions are often based on chronological age.
Harald Krenzlin   +6 more
doaj   +1 more source

Assessing Chronological Aging in Saccharomyces cerevisiae [PDF]

open access: yes, 2012
Saccharomyces cerevisiae is one of the most studied model organisms for the identification of genes and mechanisms that affect aging. The chronological lifespan (CLS) assay, which monitors the survival of a non-dividing population, is one of the two methods to study aging in yeast.
Jia, Hu   +3 more
openaire   +2 more sources

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Determining the Difference between the Chronological and Biological Age of Athletes Diagnosed with Trigeminal Neuralgia

open access: yesStudia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae
Trigeminal neuralgia induces severe, often intolerable pain in patients—athletes, in this context—that is frequently resistant to currently available therapeutic options.
Josip MIOČIĆ   +2 more
doaj   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns   +2 more
wiley   +1 more source

Raman Microspectrometry: An Alternative Method of Age Estimation from Dentin and Cementum [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Raman spectroscopy is simple, quick, sensitive and non destructive form of tissue examination that provides vital data about the structure, molecular composition and interactions within a sample.
Karuna Kumari   +4 more
doaj   +1 more source

Chronological and biological age: Why relevant for psychiatrists?

open access: yesEuropean Psychiatry, 2021
Introduction Depression is the mental disorder with the largest disease burden impact. That is due to its high prevalence, chronicty, early onset but also due to its impact on various aging-related somatic morbidities and mortality.
B. Penninx
doaj   +1 more source

Interpretation of ambiguous situations: evidence for a dissociation between social and physical threat in Williams syndrome [PDF]

open access: yes, 2011
There is increasing evidence that Williams syndrome (WS) is associated with elevated anxiety that is non-social in nature, including generalised anxiety and fears.
A Ewart   +51 more
core   +1 more source

New‐Era Polymer Thermoelectrics: Material Innovations, Doping Frontiers, Decoupling Strategies, and Unconventional Applications

open access: yesAdvanced Materials, EarlyView.
The field of polymer thermoelectrics is entering a new era, featuring breakthroughs in addressing the conventional performance disparity between p‐type and n‐type polymers, pioneering doping frontiers, and sophisticated decoupling strategies. This review explores innovations in molecular design and superior stabilities, bridging the gap from ...
Suhao Wang
wiley   +1 more source

Biological age as estimated by baseline circulating metabolites is associated with incident diabetes and mortality

open access: yesThe Journal of Nutrition, Health and Aging
Objectives: It is unclear how metabolomic assessment of biological aging performs in non-White populations and whether such an approach can predict future mortality.
La-or Chailurkit   +4 more
doaj   +1 more source

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