Results 71 to 80 of about 112,750 (310)

Biological age as estimated by baseline circulating metabolites is associated with incident diabetes and mortality

open access: yesThe Journal of Nutrition, Health and Aging
Objectives: It is unclear how metabolomic assessment of biological aging performs in non-White populations and whether such an approach can predict future mortality.
La-or Chailurkit   +4 more
doaj   +1 more source

Chronological aging leads to apoptosis in yeast [PDF]

open access: yesThe Journal of Cell Biology, 2004
During the past years, yeast has been successfully established as a model to study mechanisms of apoptotic regulation. However, the beneficial effects of such a cell suicide program for a unicellular organism remained obscure. Here, we demonstrate that chronologically aged yeast cultures die exhibiting typical markers of apoptosis, accumulate oxygen ...
Herker, Eva   +9 more
openaire   +2 more sources

New‐Era Polymer Thermoelectrics: Material Innovations, Doping Frontiers, Decoupling Strategies, and Unconventional Applications

open access: yesAdvanced Materials, EarlyView.
The field of polymer thermoelectrics is entering a new era, featuring breakthroughs in addressing the conventional performance disparity between p‐type and n‐type polymers, pioneering doping frontiers, and sophisticated decoupling strategies. This review explores innovations in molecular design and superior stabilities, bridging the gap from ...
Suhao Wang
wiley   +1 more source

CancerClock: A DNA Methylation Age Predictor to Identify and Characterize Aging Clock in Pan-Cancer

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Many biological indicators related to chronological age have been proposed. Recent studies found that epigenetic clock or DNA methylation age is highly correlated with chronological age. In particular, a significant difference between DNA methylation age
Tongtong Zhu   +12 more
doaj   +1 more source

Chronological and biological age: Why relevant for psychiatrists?

open access: yesEuropean Psychiatry, 2021
Introduction Depression is the mental disorder with the largest disease burden impact. That is due to its high prevalence, chronicty, early onset but also due to its impact on various aging-related somatic morbidities and mortality.
B. Penninx
doaj   +1 more source

Chronological age and age estimated by counting cementum annuli.

open access: yes, 2016
Plot showing the relationship between African wild dog chronological age and age estimated by counting cementum annuli of African wild dog left maxillary canines.
Gerhard Steenkamp (3216561)   +2 more
core   +1 more source

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

open access: yesAdvanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang   +10 more
wiley   +1 more source

Refining epigenetic prediction of chronological and biological age

open access: yesGenome Medicine, 2023
Background Epigenetic clocks can track both chronological age (cAge) and biological age (bAge). The latter is typically defined by physiological biomarkers and risk of adverse health outcomes, including all-cause mortality.
Elena Bernabeu   +18 more
doaj   +1 more source

Replicative and Chronological Aging in Saccharomyces cerevisiae [PDF]

open access: yesCell Metabolism, 2012
Saccharomyces cerevisiae has directly or indirectly contributed to the identification of arguably more mammalian genes that affect aging than any other model organism. Aging in yeast is assayed primarily by measurement of replicative or chronological life span. Here, we review the genes and mechanisms implicated in these two aging model systems and key
Longo, Valter D.   +3 more
openaire   +2 more sources

Age-associated hyper-methylated regions in the human brain overlap with bivalent chromatin domains

open access: yes, 2012
Recent associations between age-related differentially methylated sites and bivalently marked chromatin domains have implicated a role for these genomic regions in aging and age-related diseases. However, the overlap between such epigenetic modifications
Giulio Disanto   +18 more
core   +1 more source

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