Results 111 to 120 of about 7,947 (255)

Integration of cortical inputs in the lateral hypothalamus is dominated by the medial prefrontal cortex

The Journal of Physiology, EarlyView.
Abstract figure legend The lateral hypothalamus (LH) is a critical controller of innate behaviours such as feeding. It is anatomically connected to specific cortical areas. We mapped these areas using a combination of retrograde tracing and anterograde optogenetic circuit mapping.
Lotte J. A. M. Razenberg, Pieter Nicolaas de Greef, Huibert D. Mansvelder, Mahesh Miikael Karnani   +3 more
wiley   +1 more source

The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins, Phuong L. Ha, Connor A. Howe, Jay M. J. R. Carr, Justin A. Monteleone, Andrew J. M. Douglas, Abigail Nicholson, Andrew Steele, Brydie Lemkes, Jodie L. Koep, L. Madden Brewster, Jennifer Duffy, Mathew I. B. Debenham, Tena Monaghan, Declan Isaak, Jacob McCormick, Brian H. Dalton, Chris J. McNeil, Jared Baylis, David MacLeod, Mike Stembridge, Markus Amann, Philip N. Ainslie, Travis D. Gibbons   +23 more
wiley   +1 more source

Peter Rabbit, Dougal und Mary Poppins. Die Erzählwelten von Beatrix Potter und Emma Thompson [PDF]

, 2020
Hoffmann L. Peter Rabbit, Dougal und Mary Poppins. Die Erzählwelten von Beatrix Potter und Emma Thompson. In: Frizzoni B, Lötscher C, eds. "Bring me that horizon!" Neue Perspektiven auf Ästhetik und Praxis populärer Literaturen und Medien.
Frizzoni, Brigitte, Lötscher, Christine, Hoffmann, Lena   +2 more
core  

Formal schedulability analysis for LLM inference: TTFT and TBT deadline guarantees via response-time theory

Frontiers in Computer Science
IntroductionLarge language model (LLM) inference systems operate under strict latency service-level objectives (SLOs): a deadline on the first output token (TTFT) and a maximum inter-token interval (TBT).
Amine Marref, Khaled Tarmissi, Hassene Chaibi   +2 more
doaj   +1 more source

Influence of β-tricalcium Phosphate on the Biomechanical Dynamics of Healing of Experimental Defect of the Compact Bone [PDF]

Journal of Krishna Institute of Medical Sciences University, 2017
Background: One of the important criteria for successful treatment of bone defects with calcium phosphate osteoplastic materials is a full-fledged recovery of the biomechanical characteristics of the injured bone.
A. Korenkov
doaj  

Zinc–Adenine Metal‐Organic Frameworks for Electrochemical Detection of VCAM‐1+CD63+ Endothelial Cell‐derived Extracellular Vesicles

Electrochemical Science Advances, Volume 6, Issue 4, August 2026.
CD63‑aptamer zinc–adenine metal‐organic framework (CD63@ZnMOF) captures and concentrates extracellular vesicles (EVs) from serum before transfer to a VCAM‑1 aptamer‑modified gold electrode. This dual‐aptamer design enables specific detection of VCAM‑1+CD63+ endothelial EVs without additional redox labelling probes.
Cong Minh Nguyen, Nam‐Trung Nguyen, Hang Thu Ta   +2 more
wiley   +1 more source

Essential Information About Chronobiology and Chronotherapy for the Optimal Care of People With Bipolar Disorders: An Expert Consensus

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Introduction Circadian dysfunction is involved in the pathophysiology of bipolar disorders (BD), and circadian‐based interventions are gaining recognition in their management. Moreover, basic and epidemiologic research has generated findings inspiring circadian‐informed self‐ and clinician‐management strategies.
Jacob J. Crouse, Victoria Loblay, Anthony Jorm, Timothy R. Wong, Zsofi de Haan, Carla Gorban, Mirim Shin, Emiliana Tonini, Chris Aiken, Lauren B. Alloy, Kürşat Altinbaş, Serge Beaulieu, Joanne S. Carpenter, Bruno Etain, Yuichi Esaki, Jess G. Fiedorowicz, Corrado Garbazza, Pierre A. Geoffroy, Bartholomeus C. M. Haarman, Tone E. G. Henriksen, Maria Paz Hidalgo, Maree L. Inder, Raymond W. Lam, Helle Ø. Madsen, Colleen A. McClung, Gunnar Morken, Laura Palagini, James Phelps, Richard J. Porter, Aswin Ratheesh, Rixt F. Riemersma‐Van der Lek, Janusz K. Rybakowski, Erika F. H. Saunders, Peter F. J. Schulte, Daniel J. Smith, Holly A. Swartz, Bryan K. Tolliver, Anna Wirz‐Justice, Ian B. Hickie, John F. Gottlieb, on behalf of the Chronobiology & Chronotherapy Task Force of the International Society for Bipolar Disorders   +40 more
wiley   +1 more source

A benchmark of computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data

Genome Biology
Background CRISPR-Cas9 dropout screens are formidable tools for investigating biology with unprecedented precision and scale. However, biases in data lead to potential confounding effects on interpretation and compromise overall quality.
Alessandro Vinceti, Raffaele M. Iannuzzi, Isabella Boyle, Lucia Trastulla, Catarina D. Campbell, Francisca Vazquez, Joshua M. Dempster, Francesco Iorio   +7 more
doaj   +1 more source

TimeGPT’s Potential in Cryptocurrency Forecasting: Efficiency, Accuracy, and Economic Value

Forecasting
Accurate and efficient cryptocurrency price prediction is vital for investors in the volatile crypto market. This study comprehensively evaluates nine models—including baseline, zero-shot, and deep learning architectures—on 21 major cryptocurrencies ...
Minxing Wang, Pavel Braslavski, Dmitry I. Ignatov   +2 more
doaj   +1 more source

Clinical and Genetic Characterization of 269 Patients With Suspected Inherited Platelet Disorders: The Padua Monocentric Experience

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 856-865, August 2026.
ABSTRACT Background Inherited platelet disorders (IPDs) are rare hematologic conditions encompassing a heterogeneous spectrum of quantitative and qualitative platelet defects, frequently associated with variable clinical phenotypes and comorbidities. Accurate diagnosis necessitates comprehensive genetic characterization, detailed clinical and bleeding ...
Silvia Ferrari, Daniela Regazzo, Antonella Bertomoro, Anna Cerbo, Alessandro Galbiati, Elisabetta Cosi, Paolo Simioni   +6 more
wiley   +1 more source