Poxviruses Bearing DNA Polymerase Mutations Show Complex Patterns of Cross-Resistance
Despite the eradication of smallpox four decades ago, poxviruses continue to be a threat to humans and animals. The arsenal of anti-poxvirus agents is very limited and understanding mechanisms of resistance to agents targeting viral DNA polymerases is ...
Graciela Andrei +5 more
doaj +1 more source
Battle won, war ongoing: A call for mpox vaccination in high-risk dermatologic cases [PDF]
Atika Malik, MD +4 more
doaj +2 more sources
Resistance to antiviral drugs in human viruses from the subfamily Betaherpesvirinae
The review provides information on the mechanisms of the emergence of resistance to antiviral drugs in human viruses from the subfamily Betaherpesvirinae. Data on the principles of action of antiviral drugs and their characteristics are given.
Mikhail V. Demin +3 more
doaj +1 more source
In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet [PDF]
International ...
Croubels, Siska +6 more
core +3 more sources
Feline herpesvirus type 1 (FHV-1) commonly causes ocular surface disease in cats and is treated with antiviral medications targeting viral DNA polymerase (UL30/42).
Andrew C. Lewin +8 more
doaj +1 more source
Variability in antifungal and antiviral use in hospitalized children [PDF]
We analyzed antifungal and antiviral prescribing among high-risk children across freestanding children’s hospitals. Antifungal and antiviral days of therapy varied across hospitals.
Gerber, Jeffrey S +6 more
core +2 more sources
Antivirals against Monkeypox (Mpox) in Humans: An Updated Narrative Review
As of 29 August 2023, a total of 89,596 confirmed cases of Mpox (monkeypox) have been documented across 114 countries worldwide, with 157 reported fatalities.
Giuseppe Bruno +1 more
doaj +1 more source
Characteristics of Acyclovir-Resistant Herpes Simplex Virus Infection in Hematological Patients. [PDF]
ABSTRACT Objective Acyclovir‐resistant herpes simplex virus infections pose a significant challenge in immunosuppressed patients. This study aimed to characterize the clinical features, treatment outcomes, and mortality associated with acyclovir‐resistant herpes simplex virus infection. Materials and Methods A retrospective analysis was conducted on 18
Shehadeh R +7 more
europepmc +2 more sources
Cidofovir for the Treatment of Recurrent Respiratory Papillomatosis: A Review of the Literature [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90089/1/phco.2005.25.7.977 ...
Abramson +39 more
core +1 more source
O uso do cidofovir para papilomatose respiratória recorrente juvenil (PRRJ) ainda não tem estudos caso-controle suficientes que comprovem sua eficácia em literatura. OBJETIVO: Avaliar fatores que influenciem o prognóstico da PRRJ, e observar a atuação do
Fabiana Valera +6 more
doaj +1 more source

