Results 41 to 50 of about 13,801 (245)

Epidemiology and potential preventative measures for viral infections in children with malignancy and those undergoing hematopoietic cell transplantation. [PDF]

, 2012
In pediatric patients with malignancy and those receiving hematopoietic stem cell transplants, bacterial and fungal infections have been the focus of fever and neutropenia episodes for decades.
Alexander, Sarah, Dvorak, Christopher C, Fisher, Brian T, Sung, Lillian, Zaoutis, Theoklis E, Zerr, Danielle M   +5 more
core   +1 more source

A Multimodal Treatment Strategy to Manage Severe Cutaneous Mpox

Annals of Internal Medicine: Clinical Cases
A 33-year-old bisexual man with advanced HIV and severe mpox developed severe cutaneous disease despite receiving tecovirimat, antiretroviral therapy, and vaccinia immune globulin.
Navin Bhatt, John Winters, Yusra Shah, Victoria E. Ruiz, Ofole Mgbako, Marcia Wong, Madeline A. DiLorenzo   +6 more
doaj   +1 more source

Oral Brincidofovir Therapy for Monkeypox Outbreak: A Focused Review on the Therapeutic Potential, Clinical Studies, Patent Literature, and Prospects

Biomedicines, 2023
The monkeypox disease (MPX) outbreak of 2022 has been reported in more than one hundred countries and is becoming a global concern. Unfortunately, only a few treatments, such as tecovirimat (TCV), are available against MPX.
Mohd. Imran, Mohammed Kanan Alshammari, Mandeep Kumar Arora, Amit Kumar Dubey, Sabya Sachi Das, Mehnaz Kamal, Abdulaziz Saad Abdulrahman Alqahtani, Mohammed Ahmed Yahya Sahloly, Ahmed Hammad Alshammari, Hessah Mohammed Alhomam, Aeshah Mousa Mahzari, Abida, Ali A. Rabaan, Tafadzwa Dzinamarira   +13 more
doaj   +1 more source

Historical Perspectives in the Development of Antiviral Agents Against Poxviruses

Viruses, 2010
The poxvirus vaccinia virus (VV) served as the model virus for which the first antivirals, the thiosemicarbazones, were identified. This dates back to 1950; and, although there is at present no single antiviral drug specifically licensed for the ...
Erik De Clercq
doaj   +1 more source

Long-Term Follow-Up after Adoptive Transfer of BK-Virus-Specific T Cells in Hematopoietic Stem Cell Transplant Recipients

Vaccines, 2023
The BK virus (BKV) causes severe hemorrhagic cystitis in hematopoietic stem cell transplant (HSCT) recipients. To eliminate reactivated BKV, symptomatic patients can be treated with a reduction of the immunosuppressive therapy, with the antiviral drug ...
Michael Koldehoff, Britta Eiz-Vesper, Britta Maecker-Kolhoff, Nina K. Steckel, Ulf Dittmer, Peter A. Horn, Monika Lindemann   +6 more
doaj   +1 more source

Efficacy and Safety of Ciprofloxacin for Prophylaxis of Polyomavirus BK Virus–Associated Hemorrhagic Cystitis in Allogeneic Hematopoietic Stem Cell Transplantation Recipients [PDF]

, 2010
Polyoma virus BK–induced hemorrhagic cystitis is an important cause of morbidity after hematopoietic stem cell transplantation (HSCT). Fluoroquinolones have been shown in vitro to inhibit BK viral replication by direct inhibition of the BK-encoded DNA ...
Bowd, Kathryn, Davies, Kayt, Fulton, Janet, Lidberg, Johan, Murrell, Colleen, Richards, Ian, Ricketson, Matthew, Romano, Angela R., Sykes, Jolyon, Wake, Alexandra   +9 more
core   +2 more sources

Airway Papillomatosis: New Treatments for an Old Challenge

Frontiers in Pediatrics, 2019
Recurrent respiratory papillomatosis (RRP) is the recurrent growth of small, benign tumors, or papillomas, in the respiratory tract, caused by human papillomavirus (HPV). Currently, there is no cure.
Nankee Kumar, Diego Preciado, Diego Preciado   +2 more
doaj   +1 more source

Cidofovir for the Treatment of Molluscum Contagiosum Virus

Viruses, 2022
That cidofovir, an acyclic nucleoside phosphonate (ANP), was inhibitory to the replication of poxviruses was first demonstrated by De Clercq et al.. That its active metabolite, the diphosphate, was found to be inhibitory to the molluscum contagiosum (M ...
Erik De Clercq
doaj   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP

The Laryngoscope, EarlyView.
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best, Aaron D. Friedman, Clark A. Rosen, Robert T. Sataloff, Laura A. Matrka, H. Steven Sims, David E. Rosow, Nabil F. Saba, David G. Lott, Adam M. Klein, Ted Mau, Milan R. Amin, Kathryn A. Wikenheiser‐Brokamp, Scott M. Norberg, Kim McClellan, Geoffrey D. Young, Clint T. Allen, on behalf of the Recurrent Respiratory Papillomatosis Foundation   +17 more
wiley   +1 more source