Results 51 to 60 of about 6,983 (156)

A multi‐centre retrospective review of the bronchoscopic management of upper tracheal stenosis: an Australian perspective

open access: yesInternal Medicine Journal, Volume 56, Issue 6, Page 1019-1025, June 2026.
Abstract Background Upper tracheal stenosis (UTS) is a rare process with multiple causes and variable approaches to treatment. Australian data on management patterns are lacking and patient resources reflecting local practices are scarce. Aims To describe the management strategies of UTS over 12 years among three teaching hospitals in New South Wales ...
Nathan Harb   +6 more
wiley   +1 more source

Clinical considerations on monkeypox antiviral medications: An overview

open access: yesPharmacology Research & Perspectives
Monkeypox (mpox), a virus belonging to the orthopoxvirus family, can cause a zoonotic infectious disease with morbidity and cosmetic complications. Therefore, effective antiviral drugs with appropriate safety profiles are important for the treatment of ...
Fariba Pourkarim   +1 more
doaj   +1 more source

Refractory human cytomegalovirus infection without evidence of genetic resistance in the UL-54 and UL-97 genes in a pediatric hematopoietic stem cell transplant recipient: a case report

open access: yesFrontiers in Medicine
Cytomegalovirus (CMV) infection is a common complication in patients undergoing hematopoietic stem cell transplantation (HSCT). Management of refractory CMV infections, especially in developing countries, can be challenging due to the limited ...
Alejandra Pando-Caciano   +4 more
doaj   +1 more source

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1487-1492, May 2026.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart   +7 more
wiley   +1 more source

Antiviral Drugs for Treatment of Human Monkeypox: A Systematic Review/Meta-analysis

open access: yesMicrobes, Infection and Chemotherapy
Background. On 23 July 2022, the World Health Organization declared a Public Health Emergency of International Concern. Monkeypox is a zoonotic viral disease caused by the monkeypox virus that is transmitted from animals to humans or from human to human.
Ahmed Mohamed Abdelghany   +2 more
doaj   +1 more source

Development of CMX001 for the Treatment of Poxvirus Infections

open access: yesViruses, 2010
CMX001 (phosphonic acid, [[(S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]mono[3-(hexadecyloxy)propyl] ester) is a lipid conjugate of the acyclic nucleotide phosphonate, cidofovir (CDV).
George Painter   +10 more
doaj   +1 more source

Trends of Pathogenicity and Potential Risk Evaluation of Central African Mpox Variant to Cause Global Public Health Emergency: A Cross‐Sectional Analysis

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background With the re‐emergence of monkeypox (Mpox), it is vital for communities to assess and effectively respond to emerging outbreaks. This paper aims to review the potential of clade I Mpox to result in a widespread outbreak by assessing genetically enhanced virulence, transmission, and clinical manifestations.
Md. Ashrafur Rahman   +5 more
wiley   +1 more source

Advances in the Development of Antiviral Strategies against Parvovirus B19

open access: yesViruses, 2019
Parvovirus B19 (B19V) is a human pathogenic virus, responsible for an ample range of clinical manifestations. Infections are usually mild, self-limiting, and controlled by the development of a specific immune response, but in many cases clinical ...
Elisabetta Manaresi, Giorgio Gallinella
doaj   +1 more source

Analysis of cytomegalovirus resistance mutations and clinical features of CMV infection in immunocompromised children [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия
Objective. To determine frequency and spectrum of cytomegalovirus (CMV) resistance mutations to antiviral drugs in immunocompromised children. To study clinical course of resistant CMV infection in this patient population. Materials and Methods. This
Kozhushnaya O.S.   +4 more
doaj   +1 more source

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