Results 61 to 70 of about 8,824 (191)

Identification of Repurposed Drugs Against Monkeypox Virus Through Comprehensive Virtual Screening

Biotechnology Journal, Volume 21, Issue 8, August 2026.
Graphical Abstract and Lay Summary By combining interspecies protein analysis with advanced virtual screening, this study identifies potent repurposed drug candidates—including vindesine and LY2090314—targeting mpox DNA topoisomerase and polymerase. This workflow provides a rapid, practical framework for antiviral discovery against emerging infectious ...
Taeho Yu, Woo Dae Jang, Sang Yup Lee
wiley   +1 more source

KSHV Targeted Therapy: An Update on Inhibitors of Viral Lytic Replication

Viruses, 2014
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi’s sarcoma, primary effusion lymphoma and multicentric Castleman’s disease.
Natacha Coen, Sophie Duraffour, Robert Snoeck, Graciela Andrei   +3 more
doaj   +1 more source

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman, Karan Goel, Fernando Berton Zanchi, Aykut Ozdarendeli, Somdutt Mujwar, Ahmet E. Yetiman, Ozkan Fidan   +6 more
wiley   +1 more source

A cidofovir klinikai hatékonysága humán papillomavírus asszociált kórképekben

, 2015
A humán papillomavírus által kialakított kórképek egyre nagyobb népegészségügyi problémát jelentenek a világon. A HPV-asszociált genitális szemölcsök a szexuális promiszkuitással és a nem megfelelő szexuális higiéniával szoros összefüggést mutatnak.
Nagy, Bálint
core  

Successful Treatment of Human Herpesvirus 6 Encephalomyelitis in Immunocompetent Patient

Emerging Infectious Diseases, 2004
We report the case of human herpesvirus 6 (HHV-6) encephalomyelitis in an immunocompetent patient, which was confirmed by viral amplification from cerebrospinal fluid. Cidofovir was used followed by ganciclovir because of an adverse effect to probenecid.
Eric Denes, Laurent Magy, Karine Pradeau, Sophie Alain, Pierre Weinbreck, Sylvie Ranger-Rogez   +5 more
doaj   +1 more source

The Role of Pharmacists in Tackling Mpox: Challenges and Future Prospects: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Pharmacists play a key role in managing and mitigating mpox through clinical care, pharmacovigilance, vaccine management, and resilient supply chains. Management focuses on supportive care, infection prevention, and accurate diagnosis, with pharmacists ensuring the availability and rational use of vaccines, disinfectants ...
Ayalew Sirbemo Degebo, Fisseha Assegidew Gebretsadik, Abyou Seyfu Ambaye, Bedilu Linger Endalifer, Teshome Fentik Belachew   +4 more
wiley   +1 more source

Cidofovir for the Treatment of Molluscum Contagiosum Virus

, 2022
That cidofovir, an acyclic nucleoside phosphonate (ANP), was inhibitory to the replication of poxviruses was first demonstrated by De Clercq et al.. That its active metabolite, the diphosphate, was found to be inhibitory to the molluscum contagiosum (M ...
Erik De Clercq, De Clercq, Erik
core   +1 more source

Advances and challenges in experimental models for Epstein–Barr virus research

mLife, Volume 5, Issue 4, Page 401-416, August 2026.
Abstract Epstein–Barr virus (EBV), the first identified human oncovirus, is a ubiquitous γ‐herpesvirus etiologically linked to diverse malignancies, lymphoproliferative disorders, and autoimmune diseases. Experimental models are pivotal for unraveling the infection and pathogenesis mechanisms, life cycle regulation, as well as development and ...
Gulimire Wufuer, Jiabao Tang, Tingdong Li, Shengxiang Ge, Jun Zhang, Ningshao Xia   +5 more
wiley   +1 more source

Experiences with Cidofovir in the treatment of papillomatosis of the larynx and trachea

, 2007
Die Problematik in der chirurgischen Behandlung der rezidivierenden respiratorischen Papillomatose (RRP) stellt die aufgrund der Pathophysiologie bedingte Unmöglichkeit der Eradikation der Papillome dar.
Denk-Linnert, DM, Mancusi, G, Schickinger-Fischer, B, Bigenzahn, W   +3 more
core  

Antiviral activity of HPMPC (cidofovir) against orf virus infected lambs

, 2007
(S)-9-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPC, cidofovir, CDV, Vistide®) is an acyclic nucleoside analogue with a potent and selective activity against a broad spectrum of DNA viruses including the poxviruses.
R. Snoeck, J. Sales, J.A. Gilray, SCAGLIARINI, LORENZO, P.F. Nettleton, DAL POZZO, FABIANA, GALLINA, LAURA, C.J. McInnes, SCAGLIARINI, ALESSANDRA, PROSPERI, SANTINO   +9 more
core   +1 more source