Results 31 to 40 of about 380,265 (254)

Impact of cigarette smoke and aerobic physical training on histological and molecular markers of prostate health in rats [PDF]

Brazilian Journal of Medical and Biological Research, 2020
Recent evidence suggests that aerobic physical training may attenuate the deleterious effects of cancer risk factors, including smoking. We investigated the effects of cigarette smoke inhalation and aerobic physical training on the expression of steroid ...
A.S.C. Veras, D.B. Baptista, N.J. dos Santos, H.H.A. Thorpe, P.M. Seraphim, A.R. Florido Neto, G.R. Teixeira   +6 more
doaj   +1 more source

Estimating Toxicity Putative Mechanisms from Smoking Residual Substances Using a Whole-Cell Bioreporter System

Biosensors
Cigarette smoking is known to be an unhealthy activity that can cause a number of human diseases, including chronic obstructive pulmonary disease (COPD) and lung cancer.
Tal Bar, Marilou Shagan, Esti Kramarsky-Winter, Robert S. Marks, Karina Golberg, Ariel Kushmaro   +5 more
doaj   +1 more source

Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice

Respiratory Research, 2018
Background Cigarette smoke exposure can affect pulmonary lipid homeostasis and cause a progressive increase in pulmonary antibodies against oxidized low-density lipoproteins (OxLDL).
Maude Talbot, Mélanie Hamel-Auger, Marie-Josée Beaulieu, Morgan Gazzola, Ariane Lechasseur, Sophie Aubin, Marie-Ève Paré, David Marsolais, Ynuk Bossé, Mathieu C. Morissette   +9 more
doaj   +1 more source

Protein kinase Cβ is involved in cigarette smoke gas phase-induced ferroptosis in J774 macrophages

Journal of Pharmacological Sciences, 2023
Cigarette smoking is a risk factor for respiratory infection caused by immune cell dysfunction. Cigarette smoke is divided into tar and gas phases. Although the gas phase induces cell death in various cell types, the mechanism for gas phase-induced cell ...
Tsunehito Higashi, Haruka Handa, Yosuke Mai, Katsumi Maenaka, Takashi Tadokoro   +4 more
doaj   +1 more source

Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease [PDF]

, 2011
Chronic obstructive pulmonary disease (COPD) is a global health problem. The current therapies for COPD are poorly effective and the mainstays of pharmacotherapy are bronchodilators.
Hongwei Yao, Yao, Hongwei, Rahman, Irfan, Irfan Rahman   +3 more
core   +1 more source

Serotonin and corticosterone rhythms in mice exposed to cigarette smoke and in patients with COPD:implication for COPD-associated neuropathogenesis [PDF]

, 2014
The circadian timing system controls daily rhythms of physiology and behavior, and disruption of clock function can trigger stressful life events. Daily exposure to cigarette smoke (CS) can lead to alteration in diverse biological and physiological ...
Hongwei Yao, Lyda, Elizabeth, Sime, Patricia J, Patricia J Sime, Michael T Sellix, Isaac K Sundar, Sundar Isaac K., Yao Hongwei, Yao, Hongwei, Sellix Michael T., Sime Patricia J., Rahman Irfan, Sundar, Isaac K, Huang, Yadi, Yadi Huang, Rahman, Irfan, Irfan Rahman, Lyda Elizabeth, Elizabeth Lyda, Huang Yadi, Sellix, Michael T   +20 more
core   +1 more source

Particulate matter (PM) 2.5 levels in ETS emissions of a Marlboro Red cigarette in comparison to the 3R4F reference cigarette under open- and closed-door condition [PDF]

, 2012
Introduction Potential health damage by environmental emission of tobacco smoke (environmental tobacco smoke, ETS) has been demonstrated convincingly in numerous studies. People, especially children, are still exposed to ETS in the small space of private
Mueller Daniel, Klingelhoefer Doris, Schulze Johannes, Uibel Stefanie, Groneberg David A, Ackermann Hanns, Müller, Daniel, Schulze, Johannes B., Klingelhöfer, Doris, Uibel, Stefanie, Groneberg, Jan David Alexander, Ackermann, Hanns   +11 more
core   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease [PDF]

, 2008
RATIONALE:Abnormal inflammation and accelerated decline in lung function occur in patients with chronic obstructive pulmonary disease (COPD). Human sirtuin (SIRT1), an antiaging and antiinflammatory protein, is a metabolic NAD(+)-dependent protein ...
Rajendrasozhan, Saravanan, Kinnula, Vuokko L, Rahman, Irfan, Yang, Se-Ran   +3 more
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source