Results 161 to 170 of about 2,511 (220)
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A radioimmunoassay for the detection of ciguatoxin
Toxicon, 1977Abstract A practical, sensitive, simple and relatively specific radioimmunoassay test for the assay of ciguatoxin directly from natural sources has been developed. The radioimmunoassay test has been utilized to distinguish the toxic fishes in human ciguatera poisoning outbreaks from the nontoxic fishes.
Y, Hokama, A H, Banner, D B, Boylan
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Angewandte Chemie, 2009
AbstractEines der Haupttoxine bei Fischvergiftungen, das Ciguatoxin (siehe Struktur), war Ziel einer Totalsynthese. Der Syntheseweg beruht auf der Kupplung dreier Segmente, und die Schlüsselumwandlungen umfassen eine Komplexbildung zwischen Acetylen und Dicobalthexacarbonyl.magnified ...
Akinari, Hamajima, Minoru, Isobe
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AbstractEines der Haupttoxine bei Fischvergiftungen, das Ciguatoxin (siehe Struktur), war Ziel einer Totalsynthese. Der Syntheseweg beruht auf der Kupplung dreier Segmente, und die Schlüsselumwandlungen umfassen eine Komplexbildung zwischen Acetylen und Dicobalthexacarbonyl.magnified ...
Akinari, Hamajima, Minoru, Isobe
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2015
Ciguatera is a disease caused by the consumption of fishes from tropical and subtropical waters that have accumulated lipophilic sodium channel activator toxins known as ciguatoxins (CTXs) to levels sufficient to cause human poisoning. Consumption of these temperature-stable, orally active polycyclic ether compounds leads to the activation of neuronal ...
Lewis, Richard J., Vetter, Irina
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Ciguatera is a disease caused by the consumption of fishes from tropical and subtropical waters that have accumulated lipophilic sodium channel activator toxins known as ciguatoxins (CTXs) to levels sufficient to cause human poisoning. Consumption of these temperature-stable, orally active polycyclic ether compounds leads to the activation of neuronal ...
Lewis, Richard J., Vetter, Irina
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2014
Ciguatera is a common form of fish intoxication that is caused by ingestion of tropical fishes that have bioaccumulated the lipophilic cyclic polyether toxins know as ciguatoxins (CTXs). Consumption of these temperaturestable, orally effective sodium channel activators causes the characteristic neurological, gastrointestinal and cardiovascular symptoms
Vetter, I., Lewis, R. J.
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Ciguatera is a common form of fish intoxication that is caused by ingestion of tropical fishes that have bioaccumulated the lipophilic cyclic polyether toxins know as ciguatoxins (CTXs). Consumption of these temperaturestable, orally effective sodium channel activators causes the characteristic neurological, gastrointestinal and cardiovascular symptoms
Vetter, I., Lewis, R. J.
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Multiple ciguatoxins in the flesh of fish
Toxicon, 1992Most cases of ciguatera (fish poisoning) result from consumption of the flesh of fishes contaminated with ciguatoxin(s); however, the relatively low toxicity of ciguateric fish flesh has hindered attempts to identify these ciguatoxin(s). Utilising high performance liquid chromatography, mass spectroscopy and mouse bioassay signs we have determined that
Lewis, Richard J., Sellin, Michelle
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Ciguatoxin: More Than an Anticholinesterase
Science, 1968Anticholinesterase action of ciguatoxin has been reported. A study of the pharmacology of the action of the toxin on the respiratory system suggests that additional properties may be involved in the respiratory failure—the usual cause of death in ciguatera poisoning.
M D, Rayner, T I, Kosaki, E L, Fellmeth
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Ciguatoxins are potent ichthyotoxins
Toxicon, 1992The ciguatoxins are lipid soluble polyether compounds which have structural and biochemical features in common with the brevetoxins. Pure ciguatoxin-1, ciguatoxin-2 or brevetoxin-2 added to water containing Gambusia affinis induced similar signs, including pronounced opercular movement and uncoordinated swimming preceding death. The estimated LD50s (48
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Two interchangeable forms of ciguatoxin
Toxicon, 1984Ciguatoxin, the principal toxin responsible for ciguatera, isolated from moray eel viscera, has been separated into two distinct components by alumina chromatography. A series of chromatographies showed that the two components are interchangeable. This proves that ciguatoxin is a single molecular entity.
M, Nukina, L M, Koyanagi, P J, Scheuer
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An investigation into ciguatoxin bioaccumulation in sharks
Toxicon, 2016Ciguatoxins (CTXs) produced by benthic Gambierdiscus dinoflagellates, readily biotransform and bioaccumulate in food chains ultimately bioconcentrating in high-order, carnivorous marine species. Certain shark species, often feeding at, or near the top of the food-chain have the ability to bioaccumulate a suite of toxins, from both anthropogenic and ...
Lauren Meyer +3 more
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Ciguatoxin: Isolation and Chemical Nature
Science, 1967Ciguatoxin, the agent responsible for ciguatera, a disease produced in humans from ingestion of certain fishes, has been isolated from specimens of the moray eel, Gymnothorax javanicus . The toxin is apparently a lipid containing quaternary nitrogen, hydroxyl, and carbonyl functions.
P J, Scheuer +3 more
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