Results 121 to 130 of about 3,206 (156)
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Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC)
Journal of Cancer Research and Clinical Oncology, 2010Recently, a subset of natural killer T lymphocytes termed "cytokine-induced killer (CIK) cells" has been described. To build an international registry, we collected the clinical data and treatment of patients with cancer using CIK cells from the literature and the respective investigators.
I G H Schmidt-Wolf, Schmidt-Wolf I G H
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Cancer Immunology, Immunotherapy, 2020
Adjuvant cytokine-induced killer (CIK) cell immunotherapy has shown potential in improving the prognosis of hepatocellular carcinoma (HCC) patients after curative resection. However, whether an individual could obtain survival benefit from CIK cell treatment remains unknown. In the present study, we focused on the characteristics of CIK cells and aimed
Qiu-Zhong Pan +11 more
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Adjuvant cytokine-induced killer (CIK) cell immunotherapy has shown potential in improving the prognosis of hepatocellular carcinoma (HCC) patients after curative resection. However, whether an individual could obtain survival benefit from CIK cell treatment remains unknown. In the present study, we focused on the characteristics of CIK cells and aimed
Qiu-Zhong Pan +11 more
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Cytokine Induced Killer (CIK) cells for the treatment of haematological neoplasms
Immunology Letters, 2013Cytokine Induced Killer (CIK) cells are in vitro activated human CD8 T cells which have maintained several characteristics of T-EMRA cells and additionally acquired non specific anti tumoral cytotoxicity and CD56 overexpression, thus representing a cell population with double T and NK phenotype.
Martino Introna +2 more
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New adoptive immunotherapy strategies for solid tumours with CIK cells
Expert Opinion on Biological Therapy, 2012Despite development and introduction of new and innovative drugs, a large number of malignant diseases are associated with unfavourable prognosis. In recent years, considerable progress in cancer treatment has been obtained by the application of cytokine-induced killer (CIK) cells.This review provides an overview and summary of recent advances in ...
Amit Sharma
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Review of Chinese clinical trials on CIK cell treatment for malignancies
Clinical and Translational Oncology, 2012China is the country where the most clinical trials on CIK cells have been performed. We aimed to provide definite evidence for using CIK cell treatment and extrapolate a common applicative standard for malignancies. We chose the VIP database of Chinese scientific and technological journals to search the literature. We entered the keywords "CIK" or "xi
Changping Wu +2 more
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The effects of CIK cells on the treatment of renal cell carcinoma
The Chinese-German Journal of Clinical Oncology, 2009Objective To observe the effects of cytokine-induced killer (CIK) cells on the treatment of renal cell carcinoma.
Kaijian Lei +4 more
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Adoptive Immunotherapy Strategies with Cytokine-Induced Killer (CIK) Cells in the Treatment of Hematological Malignancies [PDF]
International Journal of Molecular Sciences, 2014 Cytokine-induced killer (CIK) cells are a heterogeneous population of immune effector cells that feature a mixed T- and Natural killer (NK) cell-like phenotype in their terminally-differentiated CD3+CD56+ subset. The easy availability, high proliferation rate and widely major histocompatibility complex (MHC)-unrestricted antitumor activity of CIK ...
Amit Sharma +2 more
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Aquatic Toxicology, 2015
The outbreak of cyanobacterial blooms induces the production and release of microcystins (MCs) into water, representing a health hazard to aquatic organisms and even humans. Some recent studies have suggested that kidney is another important target organ of MCs except liver, however, the potential toxicity mechanisms are still unclear.
Liang Chen +2 more
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The outbreak of cyanobacterial blooms induces the production and release of microcystins (MCs) into water, representing a health hazard to aquatic organisms and even humans. Some recent studies have suggested that kidney is another important target organ of MCs except liver, however, the potential toxicity mechanisms are still unclear.
Liang Chen +2 more
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Clinical expansion of cytokine induced killer (CIK) cells
ISBT Science Series, 2012Cytokine induced killer (CIK) cells are polyclonal T cells that can be expanded from marrow or peripheral blood lymphocytes with potent non‐MHC‐restricted cytotoxicity against a variety of tumor target cells. Earlier work had established the superiority of CIK cells over LAK cells in terms expansion and cytotoxicity.
M. B. C. Koh, Y. Ching Linn
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