Results 91 to 100 of about 53,999 (295)

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska   +18 more
wiley   +1 more source

A Tailored Artificial Biocatalyst for Bacterial Endophthalmitis Therapy via Enhanced Ferroptosis‐Like Death

open access: yesAdvanced Science, EarlyView.
A tailored bio‐targeted catalytic strategy based on a bacteria‐specific artificial biocatalyst (MoS2/Fe@mercaptophenylboronic acid@hyaluronic acid, MFBH) is proposed for treating bacterial endophthalmitis. This strategy exhibits high‐efficiency peptidoglycan‐targeted bactericidal efficacy in vivo following a single intravitreal injection of an ...
Caixia Sun   +9 more
wiley   +1 more source

Gaze‐Engineered 3D Augmented Reality

open access: yesAdvanced Intelligent Systems, EarlyView.
Augmented Reality (AR) systems serve as a critical interface bridging users with the metaverse. This study explores the application of human factors engineering in metaverse development, specifically investigating the integration of eye‐tracking technology to enhance AR display performance.
Naiqin Zhao   +3 more
wiley   +1 more source

Symmetry Breaking Metamaterial Sleeve Actuators

open access: yesAdvanced Intelligent Systems, EarlyView.
Metamaterial sleeves are designed to impart to a soft inflatable structure, nonlinear characteristics within the pressure–volume domain. By tuning the unit cells of the metamaterial sleeve, symmetry breaking is achieved during the inflation–deflation cycle.
Imran Qayyum Mundial   +3 more
wiley   +1 more source

Proteomic analysis of multiple primary cilia reveals a novel mode of ciliary development in mammals

open access: yesBiology Open, 2012
Summary Cilia are structurally and functionally diverse organelles, whose malfunction leads to ciliopathies. While recent studies have uncovered common ciliary transport mechanisms, limited information is available on the proteome of cilia, particularly ...
Keishi Narita   +9 more
doaj   +1 more source

Ocular Findings as the Most Striking Manifestation of a SMAD3 Variant

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Loeys‐Dietz syndrome (LDS) is a heritable connective tissue disorder with variable expressivity. It is a multisystemic condition mainly characterized by a propensity for arterial aneurysms and dissections, skeletal manifestations, hypertelorism, bifid uvula, craniosynostosis, and cutaneous features.
Noémie Villeneuve‐Cloutier   +7 more
wiley   +1 more source

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