Results 121 to 130 of about 164,456 (390)
Roles of Primary Cilia in the Developing Brain
Frontiers in Cellular Neuroscience, 2019 Essential to development, primary cilia are microtubule-based cellular organelles that protrude from the surface of cells. Acting as cellular antenna, primary cilia play central roles in transducing or regulating several signaling pathways, including ...
Sang Min Park +2 more
semanticscholar +1 more source
Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy
Advanced Robotics Research, EarlyView.Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley +1 more source
Rotating magnetic field actuation of a multicilia configuration [PDF]
, 2009 This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +3 more
core
Hydrodynamic flow patterns and synchronization of beating cilia
, 2006 We calculate the hydrodynamic flow field generated far from a cilium which is attached to a surface and beats periodically. In the case of two beating cilia, hydrodynamic interactions can lead to synchronization of the cilia, which are nonlinear ...
A. Pikovsky +9 more
core +1 more source
Primary cilia as the nexus of biophysical and hedgehog signaling at the tendon enthesis
Science Advances, 2020 Primary cilia at the tendon enthesis serve as mechanosensors and Hh signal transducers. The tendon enthesis is a fibrocartilaginous tissue critical for transfer of muscle forces to bone.
Fei Fang +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian +12 more
wiley +1 more source
BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone
bioRxiv, 2017 A diffusion barrier at the transition zone enables the compartmentalization of signaling molecules by cilia. The BBSome and the small GTPase Arl6, which triggers BBSome coat polymerization, are required for the exit of activated signaling receptors from ...
Fan Ye, Andrew R Nager, M. Nachury
semanticscholar +1 more source
Advanced Science, EarlyView.This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley +1 more source
Biology Open, 2013 Summary Primary cilia protrude from the cell surface of many cell types in the human body and function as cellular antennae via ciliary membrane localized receptors.
Livana Soetedjo +2 more
doaj +1 more source
Nature Genetics, 2017 Most monogenic cases of obesity in humans have been linked to mutations in genes encoding members of the leptin–melanocortin pathway. Specifically, mutations in MC4R, the melanocortin-4 receptor gene, account for 3–5% of all severe obesity cases in ...
J. Siljee +8 more
semanticscholar +1 more source