Results 251 to 260 of about 53,416 (270)

Impact of Race on the Outcomes of Retinoblastoma Treated With Primary Enucleation: A Global Study of 1426 Patients

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the clinical presentation, pathological features and outcomes of retinoblastoma based on the race of origin in a global cohort of patients. Methods Retrospective collaborative study of 1426 patients who underwent primary enucleation for retinoblastoma. Results Patients were grouped into Caucasians (n = 231, 16%), Asians (
Swathi Kaliki, Vijitha S. Vempuluru, Alia Ahmad, Jesse L. Berry, Rosdali Diaz‐Coronado, Maya Eiger‐Moscovich, Ido Didi Fabian, Hans Grossniklaus, G. Baker Hubbard III, Mona Mohammad, Jacob Pe'er, M. Ashwin Reddy, Mandeep S. Sagoo, Carol L. Shields, Sandra E. Staffieri, Mika Tanabe, Tatiana Ushakova, Yacoub A. Yousef, High‐Risk Retinoblastoma Collaborative Study Group, Jacob Pe’er, Mandeep S. Sagoo   +20 more
wiley   +1 more source

PKD1 mutation perturbs morphogenesis in tubular epithelial organoids derived from human pluripotent stem cells. [PDF]

Sci Rep
Scarlat A, Trionfini P, Rizzo P, Conti S, Longaretti L, Breno M, Longhi L, Xinaris C, Remuzzi G, Benigni A, Tomasoni S.   +10 more
europepmc   +1 more source

Seasonal Variation in HLA‐B27 Associated Uveitis

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To examine if there was a monthly variation in HLA‐B27‐associated uveitis. Methods Retrospective review of all individuals presenting to a single centre with HLA‐B27‐associated uveitis from 2009 to 2020. Results 577 participants with HLA‐B27‐associated uveitis were included. The median age at presentation was 40.4 years (IQR 31.1–51.
Priya D. Samalia, James Brodie, Joanne L. Sims, Rachael L. Niederer   +3 more
wiley   +1 more source

Cataract Surgery in the Small Adult Eye: A Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Modern cataract surgery continues to advance, yet intraocular lens (IOL) based surgery in the small adult eye remains challenging. Thorough preoperative assessment and surgical preparation optimise postoperative outcomes in these cases. Advances in IOL power calculation, including artificial intelligence‐driven formulas, improve accuracy ...
Jonathan E. Moore, Richard N. McNeely, Salissou Moutari   +2 more
wiley   +1 more source

Genetic Association of Primary Angle‐Closure Glaucoma and Disease Progression

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate single‐nucleotide polymorphisms (SNPs) reported in the largest up‐to‐date systematic review and meta‐analysis on primary angle‐closure disease (PACD), on their associations with primary angle‐closure glaucoma (PACG) and disease progression.
Yu Jing Liang, Anni Ling, Poemen P. Chan, Jason C. Yam, Chi Pui Pang, Clement C. Tham, Li Jia Chen   +6 more
wiley   +1 more source

In vitroapproaches to study centriole and cilium function in early mouse embryogenesis

Voelkl I, Civetta T, Egg M, Huber M, Feng S, Dammermann A, Buecker C.   +6 more
europepmc   +1 more source

ARL13B regulates juxtaposed cilia-cilia elongation in BBSome dependent manner in Caenorhabditis elegans. [PDF]

iScience
Turan MG, Kantarci H, Cevik S, Kaplan OI.   +3 more
europepmc   +1 more source

Correlation of Structure With Function: Future Utilities for Optical Coherence Tomography Angiography in Neuro‐Ophthalmology

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Optical coherence tomography angiography is a burgeoning imaging modality in Ophthalmology. In this review, we outline the breadth of potential utility for optical coherence tomography angiography for diagnosis and prognostication in neuro‐ophthalmology.
Marzieh Tahmasebi Sarvestani, Sudha Cugati, Celia Chen   +2 more
wiley   +1 more source

Tonic ubiquitination of the central body weight regulator melanocortin receptor 4 (MC4R) promotes its constitutive exit from cilia. [PDF]

PLoS Biol
Ojeda-Naharros I, Das T, Castro RA, Bazan JF, Vaisse C, Nachury MV.   +5 more
europepmc   +1 more source

Biallelic FGF4 Variants Linked to Thoracic Dystrophy and Respiratory Insufficiency

Clinical Genetics, EarlyView.
We report three people from two unrelated families with a clinical diagnosis of thoracic dystrophy characterized by short or missing ribs, narrow chest, and respiratory insufficiency. Affected people each have rare, biallelic, predicted deleterious missense substitutions in FGF4, a gene known to be essential for the formation of the thoracic skeleton ...
Laura M. Watts, Esther Kinning, Donald R. Latner, Marla Johnston, Jessica Patrick‐Esteve, Gregory M. Cooper, Stephen R. F. Twigg, Alistair T. Pagnamenta, Jenny C. Taylor   +8 more
wiley   +1 more source