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Immotile-cilia syndrome and the cilia of the eye

Albrecht von Graefes Archiv f�r klinische und experimentelle Ophthalmologie, 1981
Ten patients with the immotile-cilia syndrome were subjected to an extensive eye examination, which failed to demonstrate any consistent single abnormality. The tests of the retinal function and the aqueous humor dynamics were normal. However, different corneal abnormalities--mostly without clinical significance--were observed in 9 out of 10 patients ...
B, Svedbergh, V, Jonsson, B, Afzelius
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Alignment of cilia in immotile-cilia syndrome

Tissue and Cell, 1986
Alignment of cilia in nasal epithelial cells from eight human subjects suffering from immotile-cilia syndrome was compared with that of cells from five control subjects. Individual cilia were assessed according to the orientation of their basal feet. The range of orientation of basal feet on a single cell varied from 26 degrees to 261 degrees and 54 ...
M C, Holley, B A, Afzelius
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The structure of cilia

Biochimica et Biophysica Acta, 1955
Abstract The structure of cilia from Paramecium and from the gills of an Australian bivalve, Hyridella australis (Lam.), has been studied by means of electron microscopy. Both whole isolated cilia and sections of cilia have been examined and their fine structure elucidated.
B P, POTTS, S G, TOMLIN
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Cilia-to-Cilia Communication

Science Signaling, 2003
Many organisms, including humans, exhibit left-right (L-R) asymmetry in addition to bilateral symmetry. Molecular asymmetry, in the form of asymmetrically localized expression of lateralized genes, such as nodal , lefty-2 , and Pitx2 occurs before visible asymmetry ...
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Cilia and cilia-related disorders

New Zealand Veterinary Journal, 2006
Abstract Extract Among the puzzling aspects of the recently described autosomal recessive polycystic kidney disease (ARPKD) of sheep (Johnstone et al 2005) is the multiplicity of organ systems affected and the phenotypic variations that occur between the various animal species.
AC Johnstone, SR McGlashan, RD Jolly
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The resorption of cilia

Zeitschrift f�r Zellforschung und Mikroskopische Anatomie, 1964
Ciliary resorption, a phenomenon consistently occurring in certain protozoa, illustrates fundamental cellular processes. Membranes are observed to break and fuse in an end-to-end manner and to laminate by surface fusion within the environment of the resorption vesicle. The sequence and manner of filament degradation demonstrate the relative lability of
L E, ROTH, Y, SHIGENAKA
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Cilia Dysfunction

Otolaryngologic Clinics of North America, 2010
Cilia are complex and powerful cellular structures that serve a multitude of functions across many types of organisms. In humans, one of the most critical roles of cilia is defense of the airway. The respiratory epithelium is lined with cilia that normally carry out an integrated and coordinated mechanism called mucociliary clearance.
David A, Gudis, Noam A, Cohen
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Cilia and disease

Current Opinion in Genetics & Development, 2005
Cilia are classified according to their microtubule components as 9+2 (motile) and 9+0 (primary) cilia. Disruption of 9+2 cilia, which move mucus across respiratory epithelia, leads to rhinitis, sinusitis and bronchiectasis. Approximately half of the patients with primary ciliary dyskinesia (PCD) have situs inversus, providing a link between left-right
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