Results 51 to 60 of about 164,456 (390)
Journal of Cell Science, 2008 Descriptive has almost become a dirty word in modern cell biology. To describe something is viewed as a suitable pastime for the amateur, but hardly an occupation for the serious modern scientist.
openaire +3 more sources
A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. [PDF]
, 2017 Control of organellar assembly and function is critical to eukaryotic homeostasis and survival. Gle1 is a highly conserved regulator of RNA-dependent DEAD-box ATPase proteins, with critical roles in both mRNA export and translation.
Akef, Abdalla +2 more
core +1 more source
Microfluidic pumping using artificial magnetic cilia
, 2018 One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions.
Alexeev, Alexander +2 more
core +1 more source
PLoS Genetics, 2020 Motile cilia can beat with distinct patterns, but how motility variations are regulated remain obscure. Here, we have studied the role of the coiled-coil protein CFAP53 in the motility of different cilia-types in the mouse.
Takahiro Ide +12 more
doaj +1 more source
Smoking is associated with shortened airway cilia. [PDF]
PLoS ONE, 2009 BACKGROUND:Whereas cilia damage and reduced cilia beat frequency have been implicated as causative of reduced mucociliary clearance in smokers, theoretically mucociliary clearance could also be affected by cilia length.
Philip L Leopold +5 more
doaj +1 more source
Coordination of Cilia Movements in Multi-Ciliated Cells
Journal of Developmental Biology, 2022 Multiple motile cilia are formed at the apical surface of multi-ciliated cells in the epithelium of the oviduct or the fallopian tube, the trachea, and the ventricle of the brain. Those cilia beat unidirectionally along the tissue axis, and this provides
Masaki Arata +2 more
doaj +1 more source
Primary cilia control glucose homeostasis via islet paracrine interactions
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance The primary cilium is a small subcompartment of the cell but has powerful influence on pancreatic islet function. In this study, we find a critical role for cilia in regulating β-cell function and energy metabolism. Importantly, the deletion
Jing W. Hughes +8 more
semanticscholar +1 more source
Generation and Characterization of a Tissue-Specific Centrosome Indicator Mouse Line. [PDF]
, 2016 Centrosomes are major microtubule organizing centers (MTOCs) that play an important role in chromosome segregation during cell division. Centrosomes provide a stable anchor for microtubules, constituting the centers of the spindle poles in mitotic cells,
Chen, Ju +2 more
core +2 more sources
Diverged morphology changes of astrocytic and neuronal primary cilia under reactive insults
Molecular Brain, 2020 Primary cilia are centriole-derived sensory organelles that are present in most mammalian cells, including astrocytes and neurons. Evidence is emerging that astrocyte and neuronal primary cilia demonstrate a dichotomy in the mature mouse brain.
Ashley Sterpka +5 more
doaj +1 more source
IFT46 Expression in the Nasal Mucosa of Primary Ciliary Dyskinesia Patients: Preliminary Study
Allergy & Rhinology, 2021 Background Primary ciliary dyskinesia (PCD) is characterised by an imbalance in mucociliary clearance leading to chronic respiratory infections. Cilia length is considered to be a contributing factor in cilia movement.
Manuel Mata PhD +6 more
doaj +1 more source