Results 61 to 70 of about 53,416 (270)

Symmetry breaking cilia-driven flow in the zebrafish embryo [PDF]

J. Fluid Mech. (2012), vol. 705, pp. 26-45, 2013
Fluid mechanics plays a vital role in early vertebrate embryo development, an example being the establishment of left-right asymmetry. Following the dorsal-ventral and anterior-posterior axes, the left-right axis is the last to be established; in several species it has been shown that an important process involved with this is the production of a left ...
arxiv   +1 more source

Magnetoelastic Sensing: A Study of Flexible Magnetoelastic Strain Sensors for Highly Deformed Posture Perception

Advanced Materials Technologies, EarlyView.
This study proposes a magnetoelastic strain sensor for highly deformed posture perception. The sensor can maintain stable sensing signal output under significant strain (200%) and at varying stretch rates (ranging from 1000 to 8000 mm min−1). The sensor design is simple and can be applied to soft robots and wearable devices.
Jing Shu, Junming Wang, Yujie Su, Minghao Liu, Yehui Li, Hsuan‐Yu Lu, Md Masruck Alam, Chun‐Hang Eden Ti, Shuk Fan Tong, Zhaoli Gao, Zhao Guo, Zheng Li, Raymond Kai‐yu Tong   +12 more
wiley   +1 more source

Volume‐rendered optical coherence tomography angiography during ocular interventions: Advocating for noninvasive intraoperative retinal perfusion monitoring

Journal of Biophotonics, Volume 15, Issue 12, December 2022., 2022
In ophthalmic surgery, intraoperative retinal perfusion assessment/monitoring has been suggested for numerous indications, typically using fluorescence angiography. However, applicability is limited given the difficult arrangement, associated risks and the lack of automated/objective perfusion quantification.
Tim J. Enz, Peter M. Maloca, Markus Tschopp, Marcel N. Menke, James R. Tribble, Pete A. Williams, Nadja Inglin, Ulrike Steitz, Hendrik P. N. Scholl, Anthia Papazoglou   +9 more
wiley   +1 more source

A boundary element regularised Stokeslet method applied to cilia and flagella-driven flow [PDF]

Proceedings of the Royal Society of London Series A, 465, 3605-3626 (2009), 2010
A boundary element implementation of the regularised Stokeslet method of Cortez is applied to cilia and flagella-driven flows in biology. Previously-published approaches implicitly combine the force discretisation and the numerical quadrature used to evaluate boundary integrals.
arxiv   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

IFT88 Plays a Cilia- and PCP-Independent Role in Controlling Oriented Cell Divisions during Vertebrate Embryonic Development

Cell Reports, 2013
The role for cilia in establishing planar cell polarity (PCP) is contentious. Although knockdown of genes known to function in ciliogenesis has been reported to cause PCP-related morphogenesis defects in zebrafish, genetic mutations affecting ...
Antonia Borovina, Brian Ciruna
doaj   +1 more source

Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia

Frontiers in Cell and Developmental Biology, 2021
Cilia are evolutionarily highly conserved organelles with important functions in many organs. The extracellular component of the cilium protruding from the plasma membrane comprises an axoneme composed of microtubule doublets, arranged in a 9 + 0 ...
Paweł K. Łysyganicz, Paweł K. Łysyganicz, Niedharsan Pooranachandran, Xinming Liu, Kathryn I. Adamson, Kathryn I. Adamson, Katarzyna Zielonka, Katarzyna Zielonka, Stone Elworthy, Stone Elworthy, Fredericus J. van Eeden, Fredericus J. van Eeden, Andrew J. Grierson, Andrew J. Grierson, Jarema J. Malicki, Jarema J. Malicki   +15 more
doaj   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Designing metachronal waves of cilia [PDF]

arXiv, 2020
On surfaces with many motile cilia, beats of the individual cilia coordinate to form metachronal waves. We present a theoretical framework that connects the dynamics of an individual cilium to the collective dynamics of a ciliary carpet via systematic coarse-graining.
arxiv  

Programmable metachronal motion of densely packed magnetic artificial cilia [PDF]

arXiv, 2023
Despite recent advances in artificial cilia technologies, the application of metachrony, which is the collective wavelike motion by cilia moving out-of-phase, has been severely hampered by difficulties in controlling densely packed artificial cilia at micrometer length scales. Moreover, there has been no direct experimental proof yet that a metachronal
arxiv