Results 211 to 220 of about 30,170 (290)

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

Pediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang, Fuping Yang, Chunyu Yan, Yu Deng, Enmei Liu   +4 more
wiley   +1 more source

Antarctic Krill with parasites grow slower than uninfected peers. [PDF]

Mar Biol
Cleary AC, Kawaguchi S, King R, Melvin JE, Tarling GA.   +4 more
europepmc   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Artifact-free preparation of biological samples for SEM by optimized water freeze-drying. [PDF]

Sci Rep
Ishida H, Fukuda N, Shimada M, Yamamoto K, Gaponova L, Higuchi R, Kolosiuk A, Hoshina R, Arikawa M, Fukuda Y, Islam MDS, Harumoto T, Wan Y, Itoh T, Inai Y, Takeishi A, Aonuma H, Kikuchi T, Nishigori S, Maruyama T, Ikeda K, Iriko H, Suzaki T.   +22 more
europepmc   +1 more source

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Functions and mechanisms of eukaryotic RNA-guided programmed DNA elimination. [PDF]

Biochem Soc Trans
Stefanov BA, Nowacki M.
europepmc   +1 more source

Optimization of Microfluidic Geometry for Extracellular Vesicle Capture Using an Automated Parallel Pattern Search

PROTEOMICS, EarlyView.
ABSTRACT Microfluidic affinity‐based capture of extracellular vesicles (EVs) holds great promise for disease diagnostics and monitoring therapeutic EV production. However, optimizing microfluidic channel geometries for efficient EV capture remains understudied due to the effort required to experimentally test numerous designs.
Arvin Lim, A. J. Tyler, Isha Nayyar, Larry W. Chamley, Cherie Blenkiron, Colin L. Hisey, Richard J. Clarke   +6 more
wiley   +1 more source

Taxonomy and molecular phylogeny of nassulid ciliates (Alveolata, Ciliophora) with descriptions of one new genus and three new species. [PDF]

BMC Microbiol
Sun Q, Jiang L, Liu M, Hu X.
europepmc   +1 more source