Results 91 to 100 of about 34,354 (355)
NPHP proteins are binding partners of nucleoporins at the base of the primary cilium.
PLoS ONE, 2019 Cilia are microtubule-based organelles that protrude from the surface of eukaryotic cells to generate motility and to sense and respond to environmental cues.
T Lynne Blasius +2 more
doaj +1 more source
Poc1B and Sas-6 Function Together during the Atypical Centriole Formation in Drosophila melanogaster
Cells, 2019 Insects and mammals have atypical centrioles in their sperm. However, it is unclear how these atypical centrioles form. Drosophila melanogaster sperm has one typical centriole called the giant centriole (GC) and one atypical centriole called the proximal
Kyoung H. Jo +5 more
doaj +1 more source
Mathematical modelling of cilia driven transport of biological fluids [PDF]
, 2009 Cilia-driven flow occurs in the airway surface liquid, in the female and male reproductive tracts and enables symmetry-breaking in the embryonic node. Viscoelastic rheology is found in healthy states in some systems, whereas in others may characterise ...
Blake, J R, Gaffney, E. A., Smith, D J
core +1 more source
Interfacial Yield Stress Response in Synthetic Mucin Solutions
Advanced Materials Interfaces, EarlyView.The solution rheology of novel synthetic mucins mimicking natural mucin domains is studied. Like many natural mucin solutions, apparent solid‐like rheology is seen. However, no bulk structural features are found to explain it. Interfacial rheology and robust modelling reveal that this arises from molecular associations at the air–water interface ...
Sumit Sunil Kumar +7 more
wiley +1 more source
Shortened primary cilium length and dysregulated Sonic hedgehog signaling in Niemann-Pick C1 disease [PDF]
, 2017 The Niemann-Pick type C1 (NPC1) disease is a neurodegenerative lysosomal storage disorder due to mutations in the NPC1 gene, encoding a transmembrane protein related to the Sonic hedgehog receptor, Patched, and involved in intracellular trafficking of ...
Canterini, Sonia +7 more
core +1 more source
Trafficking to the primary cilium membrane
Molecular Biology of the Cell, 2017 The primary cilium has been found to be associated with a number of cellular signaling pathways, such as vertebrate hedgehog signaling, and implicated in the pathogenesis of diseases affecting multiple organs, including the neural tube, kidney, and brain. The primary cilium is the site where a subset of the cell's membrane proteins is enriched. However,
Kasturi Pal +5 more
openaire +3 more sources
Advanced Materials Technologies, EarlyView.This study proposes a magnetoelastic strain sensor for highly deformed posture perception. The sensor can maintain stable sensing signal output under significant strain (200%) and at varying stretch rates (ranging from 1000 to 8000 mm min−1). The sensor design is simple and can be applied to soft robots and wearable devices.
Jing Shu +12 more
wiley +1 more source
Cilium Expression Score Predicts Glioma Survival
Frontiers in Genetics, 2021 The accurate classification, prognostication, and treatment of gliomas has been hindered by an existing cellular, genomic, and transcriptomic heterogeneity within individual tumors and their microenvironments.
Srinivas Rajagopalan +3 more
doaj +1 more source
A role for Tctex-1 (DYNLT1) in controlling primary cilium length [PDF]
, 2011 The microtubule motor complex cytoplasmic dynein is known to be involved in multiple processes including endomembrane organization and trafficking, mitosis, and microtubule organization.
MacCarthy-Morrogh, LJ +3 more
core +1 more source
Advanced Science, EarlyView.Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei +15 more
wiley +1 more source