Results 91 to 100 of about 41,549 (330)
Dynamic curvature regulation accounts for the symmetric and asymmetric beats of Chlamydomonas flagella [PDF]
, 2015 Axonemal dyneins are the molecular motors responsible for the beating of cilia and flagella. These motors generate sliding forces between adjacent microtubule doublets within the axoneme, the motile cytoskeletal structure inside the flagellum.
Geyer, Veikko +4 more
core +2 more sources
Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine
Advanced Materials, EarlyView.A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen +5 more
wiley +1 more source
Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding
PLOS Biology, 2019 The primary cilium is a central signaling hub in cell proliferation and differentiation and is built and disassembled every cell cycle in many animal cells. Disassembly is critically important, as misregulation or delay of cilia loss leads to cell cycle defects. The physical means by which cilia are lost are poorly understood but are thought to involve
Mary Mirvis +3 more
openaire +4 more sources
The photoreceptor cilium and its diseases [PDF]
Current Opinion in Genetics & Development, 2019 Light sensation occurs in photoreceptor outer segments (OS), which derive from highly specialized primary cilia, based on structural and molecular similarities. Ciliary dysfunction causes ciliopathies, in which retinal degeneration is common. The connecting cilium (CC) is the obligate passage for proteins moving between ciliary and cellular compartment,
Bachmann-Gagescu, Ruxandra +1 more
openaire +2 more sources
The Space Within: How Architected Voids Promote Tissue Formation
Advanced Materials, EarlyView.This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou +3 more
wiley +1 more source
Comparative Biology of Centrosomal Structures in Eukaryotes
Cells, 2018 The centrosome is not only the largest and most sophisticated protein complex within a eukaryotic cell, in the light of evolution, it is also one of its most ancient organelles.
Ralph Gräf
doaj +1 more source
Stem Cell Research, 2020 The primary cilium acts as a sensory organelle with diverse receptors and ion channels to detect extracellular cues and regulate cellular functions, including cell migration.
Mi Nam Lee +7 more
doaj +1 more source
CXCL12 targets the primary cilium cAMP/cGMP ratio to regulate cell polarity during migration
Nature Communications, 2023 Directed cell migration requires sustained cell polarisation. In migrating cortical interneurons, nuclear movements are directed towards the centrosome that organises the primary cilium signalling hub.
Melody Atkins +5 more
doaj +1 more source
Primary Cilium in Cancer Hallmarks
International Journal of Molecular Sciences, 2019 The primary cilium is a solitary, nonmotile and transitory appendage that is present in virtually all mammalian cells. Our knowledge of its ultrastructure and function is the result of more than fifty years of research that has dramatically changed our perspectives on the primary cilium.
Fabbri, Lucilla +2 more
openaire +3 more sources
Physical Intelligence in Small‐Scale Robots and Machines
Advanced Materials, EarlyView.“Physical intelligence” (PI) empowers biological organisms and artificial machines, especially at the small scales, to perceive, adapt, and even reshape their complex, dynamic, and unstructured operation environments. This review summarizes recent milestones and future directions of PI in small‐scale robots and machines.
Huyue Chen, Metin Sitti
wiley +1 more source