Dynamic curvature regulation accounts for the symmetric and asymmetric beats of Chlamydomonas flagella [PDF]
Axonemal dyneins are the molecular motors responsible for the beating of cilia and flagella. These motors generate sliding forces between adjacent microtubule doublets within the axoneme, the motile cytoskeletal structure inside the flagellum.
Geyer, Veikko +4 more
core +2 more sources
Advancing from MOFs and COFs to Functional Macroscopic Porous Constructs
This review study investigates the recent progress and methodologies for manufacturing metal–organic framework (MOF) or covalent–organic framework (COF)‐based 3D structured macroscopic porous constructs with high structural integrity, providing the possibility to control their porosity across dimensions.
Seyyed Alireza Hashemi +8 more
wiley +1 more source
Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish [PDF]
Background: In mammalian cells, the integrity of the primary cilium is critical for proper regulation of the Hedgehog (Hh) signal transduction pathway.
Ingham, P.W. +3 more
core +3 more sources
Enteric neurons show a primary cilium [PDF]
AbstractThe primary cilium is a non‐motile cilium whose structure is 9+0. It is involved in co‐ordinating cellular signal transduction pathways, developmental processes and tissue homeostasis. Defects in the structure or function of the primary cilium underlie numerous human diseases, collectively termed ciliopathies.
Mario Soriano +5 more
openaire +5 more sources
Interactions Between Active Matters and Endogenous Fields
This review synthesizes endogenous field information and computational methods in contexts such as cancer, wounds, and biofilms. It organizes NAMs and AAMs by sensing, transmitting, and executing functions, compares their limitations, and from these contrasts proposes design strategies for next‐generation AAMs, offering perspectives to foster ...
Jinwei Lin +6 more
wiley +1 more source
Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys
Hypoxic environments at high altitude have significant effects on kidney injury. Following injury, renal primary cilia display length alterations. Primary cilia are mechanosensory organelles that regulate tubular architecture.
Kiumars Shamloo +9 more
doaj +1 more source
Functional divergence in the role of N-linked glycosylation in smoothened signaling [PDF]
The G protein-coupled receptor (GPCR) Smoothened (Smo) is the requisite signal transducer of the evolutionarily conserved Hedgehog (Hh) pathway. Although aspects of Smo signaling are conserved from Drosophila to vertebrates, significant differences have ...
A Helenius +83 more
core +3 more sources
Physical Intelligence in Small‐Scale Robots and Machines
“Physical intelligence” (PI) empowers biological organisms and artificial machines, especially at the small scales, to perceive, adapt, and even reshape their complex, dynamic, and unstructured operation environments. This review summarizes recent milestones and future directions of PI in small‐scale robots and machines.
Huyue Chen, Metin Sitti
wiley +1 more source
Soft Robotic Engines with Non‐Reciprocal Motion by Physical Intelligence
Movement is vital, and it requires breaking symmetry. This study introduces a hydrogel engine that achieves non‐reciprocal motion through kinetic asymmetry in repeated actuation cycles. This approach for breaststroke‐swimming‐like motion is embedded inside the material and establishes a new paradigm of physical intelligence for soft robotics.
Oliver Skarsetz +10 more
wiley +1 more source
Primary cilia are microtubule-based organelles, which protrude from the plasma membrane and receive a wide range of extracellular signals. Various cilia use G protein-coupled receptors (GPCRs) for the detection of these signals.
Celine Brooks +7 more
doaj +1 more source

