Basal paravian functional anatomy illuminated by high-detail body outline [PDF]
Nature Communications, 2017 Soft tissues are rarely preserved in the fossil record; therefore, body shape of extinct vertebrates is usually inferred indirectly. Here, the authors use laser-stimulated fluorescence of fossils to detect and reconstruct the body outline of the paravian
Xiaoli Wang +6 more
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Katanin localization requires triplet microtubules in Chlamydomonas reinhardtii. [PDF]
PLoS ONE, 2013 Centrioles and basal bodies are essential for a variety of cellular processes that include the recruitment of proteins to these structures for both centrosomal and ciliary function.
Jessica M Esparza +6 more
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Intrinsic clustering of flagellar basal body proteins in E. coli: A self-organization mechanism for assembly and regulation [PDF]
Biochemistry and Biophysics ReportsThe assembly and spatial organization of flagellar basal bodies in Escherichia coli are crucial for motility and chemotaxis. Using fluorescence and single-molecule microscopy, we demonstrate that key basal body proteins, FliF and FlhA, self-organize into
Yun-Sing Sung, De-Fa Hong, Yi-Ren Chang
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A basal body microtubule singlet-to-doublet transition in Plasmodium male gametogenesis [PDF]
Nature CommunicationsAxoneme assembly constitutes a pivotal process in male gametogenesis of Plasmodium. Plasmodium possesses a unique nuclear envelope-anchored basal body that templates axoneme assembly, distinct from the basal body that templates the axoneme of cilia or ...
Shuzhen Yang +8 more
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The structure of basal body inner junctions from Tetrahymena revealed by electron cryo-tomography [PDF]
EMBO JournalSam Li +2 more
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Journal of Developmental Biology, 2022 The development of multicellular organisms requires a tightly coordinated network of cellular processes and intercellular signalling. For more than 20 years, it has been known that primary cilia are deeply involved in the mediation of intercellular ...
Thorsten Pfirrmann, Christoph Gerhardt
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Paramecium, a Model to Study Ciliary Beating and Ciliogenesis: Insights From Cutting-Edge Approaches
Frontiers in Cell and Developmental Biology, 2022 Cilia are ubiquitous and highly conserved extensions that endow the cell with motility and sensory functions. They were present in the first eukaryotes and conserved throughout evolution (Carvalho-Santos et al., 2011).
K. Bouhouche +8 more
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Microtubule Organizing Centers Contain Testis-Specific γ-TuRC Proteins in Spermatids of Drosophila
Frontiers in Cell and Developmental Biology, 2021 Microtubule nucleation in eukaryotes is primarily promoted by γ-tubulin and the evolutionary conserved protein complex, γ-Tubulin Ring Complex (γ-TuRC).
Elham Alzyoud +6 more
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Intraflagellar transport protein RABL5/IFT22 recruits the BBSome to the basal body through the GTPase ARL6/BBS3 [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2020 Bin Xue, Yan-Xia Liu, Bin Dong
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Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis
Cell Reports, 2018 Ciliopathies are a group of genetic disorders caused by a failure to form functional cilia. Due to a lack of structural information, it is currently poorly understood how ciliopathic mutations affect protein functionality to give rise to the underlying ...
Nimesh Joseph +7 more
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