Results 121 to 130 of about 34,354 (355)

Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering

Aggregate, EarlyView.
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang, Alice Le Friec, Menglin Chen, Di Sun   +3 more
wiley   +1 more source

Deciphering vesicle-assisted transport mechanisms in cytoplasm to cilium trafficking

Frontiers in Cellular Neuroscience
The cilium, a pivotal organelle crucial for cell signaling and proper cell function, relies on meticulous macromolecular transport from the cytoplasm for its formation and maintenance.
Mark Tingey, Andrew Ruba, Zechang Jiang, Weidong Yang   +3 more
doaj   +1 more source

Targeting the HDAC6‐Cilium Axis Ameliorates the Pathological Changes Associated with Retinopathy of Prematurity

Advanced Science, 2022
Retinopathy of prematurity (ROP) is one of the leading causes of childhood visual impairment and blindness. However, there are still very few effective pharmacological interventions for ROP.
Jie Ran, Yao Zhang, Sai Zhang, Haixia Li, Liang Zhang, Qingchao Li, Juan Qin, Dengwen Li, Lei Sun, Songbo Xie, Xiaomin Zhang, Lin Liu, Min Liu, Jun Zhou   +13 more
doaj   +1 more source

Dynamics of the Primary Cilium in Shear Flow [PDF]

Biophysical Journal, 2012
In this work, the equilibrium shape and dynamics of a primary cilium under flow are investigated by using both theoretical modeling and experiment. The cilium is modeled as an elastic beam that may undergo large deflection due to the hydrodynamic load. Equilibrium results show that the anchoring effects of the basal body on the cilium axoneme behave as
Christopher R. Jacobs, Yuan-Nan Young, Matthew Downs   +2 more
openaire   +4 more sources

Advances in 3D and 4D Printing of Soft Robotics and Their Applications

Advanced Intelligent Systems, EarlyView.
This article summarizes the development of 3D‐printed soft robotics in the recent decade. The article discusses the printing capabilities of different additive manufacturing technologies in terms of soft polymers, multimaterial printability, soft robotic printing, and 4D printing.
Hao Liu, Changchun Wu, Senyuan Lin, James Lam, Ning Xi, Yonghua Chen   +5 more
wiley   +1 more source

Volume‐rendered optical coherence tomography angiography during ocular interventions: Advocating for noninvasive intraoperative retinal perfusion monitoring

Journal of Biophotonics, Volume 15, Issue 12, December 2022., 2022
In ophthalmic surgery, intraoperative retinal perfusion assessment/monitoring has been suggested for numerous indications, typically using fluorescence angiography. However, applicability is limited given the difficult arrangement, associated risks and the lack of automated/objective perfusion quantification.
Tim J. Enz, Peter M. Maloca, Markus Tschopp, Marcel N. Menke, James R. Tribble, Pete A. Williams, Nadja Inglin, Ulrike Steitz, Hendrik P. N. Scholl, Anthia Papazoglou   +9 more
wiley   +1 more source

The primary cilium directs osteopontin-induced migration of mesenchymal stem cells by regulating CD44 signaling and Cdc42 activation

Stem Cell Research, 2020
The primary cilium acts as a sensory organelle with diverse receptors and ion channels to detect extracellular cues and regulate cellular functions, including cell migration.
Mi Nam Lee, Ju Han Song, Sin-Hye Oh, Nguyen Thi Tham, Jung-Woo Kim, Jin-Woo Yang, Eung-Sam Kim, Jeong-Tae Koh   +7 more
doaj  

A simple protocol to automate the executing, scaling, and reconfiguration of Cloud-Native Apps [PDF]

arXiv, 2023
We propose a simple protocol for Service Mesh management. The protocol specification consists of the formats of messages, and the actions taken by senders and recipients. The idea is that microservices of Cloud-Native Application should be also involved in configurations of their communication sessions.
arxiv  

Retinitis Pigmentosa GTPase Regulator (RPGR) protein isoforms in mammalian retina:insights into X-linked Retinitis Pigmentosa and associated ciliopathies [PDF]

, 2008
Mutations in the cilia-centrosomal protein Retinitis Pigmentosa GTPase Regulator (RPGR) are a frequent cause of retinal degeneration. The RPGR gene undergoes complex alternative splicing and encodes multiple protein isoforms. To elucidate the function of
Akimoto, Anand Swaroop, Baala, Babak Behnam, Badano, Ben Margolis, Besharse, Bird, Boylan, Brancati, Breuer, Buraczynska, Cai, Chang, den Hollander, Deretic, Doxsey, Ferreira, Fishman, Fishman, Fleischman, Follit, Fujita, Fujita, Gieser, Han, Haycraft, Hemant Khanna, Hong, Hong, Hong, Hong, Hong, Hong, Hunter, Iannaccone, Jay, Kapranov, Khanna, Kim, Kirschner, Koenekoop, Linari, Liu, Liu, Low, Lu, Lu, Mavlyutov, Mears, Meindl, Melamud, Moore, Moritz, Neidhardt, Otto, Perrault, Renault, Roepman, Roepman, Rosenbaum, Rosenbaum, Sayer, Schwahn, Sharon, Shirley He, Shu, Shu, Singla, Sunil K. Parapuram, Toby W. Hurd, Tsvetkov, Valente, van Dorp, Vervoort, Vervoort, Wright, Yan, Young, Zhang, Zito   +80 more
core   +1 more source

Direction selection of metachronal waves in hydrodynamic coordination of cilia [PDF]

arXiv, 2023
Large arrays of active cilia coordinate their beat cycles into metachronal waves. These waves can travel in different directions with respect to the cilium's beat direction and the resulting direction of fluid propulsion. Hydrodynamic interactions provide a mechanism for the individual cilia to coordinate their beat cycles.
arxiv