Results 121 to 130 of about 40,574 (330)

Robotic Materials With Bioinspired Microstructures for High Sensitivity and Fast Actuation

Advanced Science, EarlyView.
In the review paper, design rationale and approaches for bioinspired sensors and actuators in robotics applications are presented. These bioinspired microstructure strategies implemented in both can improve the performance in several ways. Also, recent ideas and innovations that embed robotic materials with logic and computation with it are part of the
Sakshi Sakshi, Rohit Pratyush Behera, Hongyu Zhou, Yifan Wang, Hortense Le Ferrand   +4 more
wiley   +1 more source

Cell-wide arrangement of Golgi/RE units depends on the microtubule organization

Cell Structure and Function
We have previously shown that Golgi stacks and recycling endosomes (REs) exist as Golgi/RE units in sea urchin embryos. In this study, we showed that Golgi/RE units were scattered throughout the cytoplasm at early developmental stages but gathered to ...
Tatsuya Tago, Syara Fujii, Shogo Sasaki, Maki Shirae-Kurabayashi, Naoaki Sakamoto, Takashi Yamamoto, Makoto Maeda, Tatsuya Ueki, Takunori Satoh, Akiko K. Satoh   +9 more
doaj   +1 more source

Taking Vesicular Transport to the Cilium [PDF]

Cell, 2007
Defects in protein trafficking within the cell body and cilia are thought to underlie the human disease Bardet-Biedl syndrome (BBS). In this issue, Nachury et al. (2007) reveal that a large complex of proteins implicated in BBS cooperates with Rabin8-the GTP exchange factor for the small GTPase Rab8-to promote cilia formation and presumably movement of
openaire   +3 more sources

ARL3 Enhances ERα Stability via USP10 Deubiquitination to Promote Endocrine Resistance and Drive Mitochondrial Metabolic Reprogramming in HR+ Breast Cancer

Advanced Science, EarlyView.
This study identifies ADP‐ribosylation factor‐like protein 3 (ARL3) as a novel chaperone that stabilizes estrogen receptor α (ERα) in breast cancer. ARL3 promotes tumor growth by recruiting USP10 to remove ubiquitin chains from ERα, preventing its degradation.
Han Li, Yang Liu, Zehao Cai, Kang Li, Shun Gao, Ailin Lan, Dan Shu, Kuan He, Xin Liu, Yang Peng, Shipeng Guo, Haochen Yu, Aishun Jin, Meiying Shen, Shengchun Liu   +14 more
wiley   +1 more source

CFAP410 has a bimodular architecture with a conserved surface patch on its N-terminal leucine-rich repeat motif for binding interaction partners

Frontiers in Cell and Developmental Biology
Cilia and flagella associated protein 410 (CFAP410) is a protein localized at the basal body of cilia/flagella and plays essential roles in ciliogenesis. Multiple single amino acid mutations in CFAP410 have been identified in patients.
Alexander Stadler, Alexander Stadler, Heloisa B. Gabriel, Laryssa V. De Liz, Santiago Alonso-Gil, Santiago Alonso-Gil, Xuan Deng, Robbie Crickley, Katharina Korbula, Katharina Korbula, Barbora Mikolaskova, Barbora Mikolaskova, Sue Vaughan, Kaiyao Huang, Bojan Žagrović, Bojan Žagrović, Jack D. Sunter, Gang Dong, Gang Dong   +18 more
doaj   +1 more source

Learning to Navigate in Chemical Fields Without A Map at Low Reynolds Numbers

Advanced Science, EarlyView.
Deep reinforcement learning enables a reconfigurable artificial microswimmer to exhibit run‐and‐tumble strategy to navigate toward a chemical source. This mapless microswimmer can robustly navigate in diverse chemical fields without relying on a pre‐existing map.
Yangzhe Liu, On Shun Pak, Alan C. H. Tsang   +2 more
wiley   +1 more source

Unexpected encounter with an intracameral cilium postcataract surgery

The Pan-American Journal of Ophthalmology
Background: Cataract surgery, a routine and highly successful ophthalmic intervention, is not immune to unexpected challenges. While complications are infrequent, their diverse nature necessitates a thorough understanding to ensure optimal patient ...
Anchal Tripathi, Atul Bhirud, Mohini Agrawal, Avinash Mishra, Biresh Raj   +4 more
doaj   +1 more source

The $Ca^{2+}$-activated $Cl^-$ current ensures robust and reliable signal amplification in vertebrate olfactory receptor neurons

, 2018
Activation of most primary sensory neurons results in transduction currents that are carried by cations. One notable exception is the vertebrate olfactory receptor neuron (ORN), where the transduction current is carried largely by the anion $Cl ...
Reingruber, Jürgen, Reisert, Johannes
core  

Inhaling Eugenol Inhibits NAFLD by Activating the Hepatic Ectopic Olfactory Receptor Olfr544 and Modulating the Gut Microbiota

Advanced Science, EarlyView.
Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang, Zhan‐Zhan Li, Shu‐Ding Sun, Ya‐Gang Song, Jin‐Xin Miao, Xiang‐Xiang Wu, Yong‐Li Han, Xiao‐Lei Zhang, Wen‐Jing Chen, Qing‐Hua Wang, Yu Zhang, Yiping Fu, Yu‐ting Liu, Lin‐yan Lang, Wen‐Xia Zhao, Ming‐San Miao   +15 more
wiley   +1 more source

Retinitis Pigmentosa‐Associated Gene TRIM49 Regulates ULK1‐Mediated Autophagy and Photoreceptor Phagocytosis by the Retinal Pigment Epithelium

Advanced Science, EarlyView.
Based on next‐generation sequencing data of retinitis pigmentosa (RP) patients and controls, this study identifies TRIM49 as a novel gene for autosomal recessive RP. TRIM49 is specifically expressed in the retinal pigment epithelium (RPE) of human retina.
Zhen Yi, Chaojuan Wen, Han Du, Yingwei Wang, Shuowei Chen, Jie Liu, Shuhan Zhang, Junwen Wang, Xueshan Xiao, Shiqiang Li, Xiaoyun Jia, Yi Jiang, Jiamin Ouyang, Panfeng Wang, James Fielding Hejtmancik, Wenmin Sun, Huangxuan Shen, Qingjiong Zhang   +17 more
wiley   +1 more source