Results 21 to 30 of about 1,660 (165)

Wenyang Decoction Ameliorates DSS-Induced Ulcerative Colitis by Regulating Macrophage Polarization and the PI3K/AKT/mTOR/HIF-1α Signaling Pathway. [PDF]

open access: yesMediators Inflamm
Aim Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by intestinal inflammation and epithelial damage. This study aims to investigate the therapeutic effects of Wenyang decoction (WYD) in a dextran sulfate sodium (DSS)‐induced UC model and its underlying mechanisms, with a focus on macrophage polarization and the regulation
Li S, Yuan G, Chen C, Lu J, Zhang X.
europepmc   +2 more sources

Pharmacoinformation analysis of the molecules of the drug Klimaktoplan

open access: yesФармакокинетика и Фармакодинамика, 2018
An analysis of an array of publications on naturaL extracts of tsimitsifuga, sepia, sanguinaria included in the preparation KLimaktoplan, showed that only the extracts of tsimitsifugi have more than 800 studies.
I. Yu. Torshin   +2 more
doaj   +1 more source

A comparison of the effects of estrogen and Cimicifuga racemosa on the lacrimal gland and submandibular gland in ovariectomized rats. [PDF]

open access: yesPLoS ONE, 2015
This study aims to observe the effects of estradiol and Cimicifuga racemosa on the lacrimal gland and submandibular gland of ovariectomized rats. We randomly divided 20 adult female SD rats into four groups-a sham-operated group (SHAM), ovariectomized ...
Yunmeng Da   +9 more
doaj   +1 more source

Ferulic Acid Alleviates Inflammation and Promotes Osteogenic Differentiation in Periodontitis by Inhibiting NF-<i>κ</i>B Pathway. [PDF]

open access: yesStem Cells Int
Background Periodontitis refers to a chronic inflammatory illness that induces the destruction of periodontal tissues and can be driven by bacterial lipopolysaccharide (LPS) of pathogens. This study investigated the anti‐inflammatory potential and underlying mechanisms of ferulic acid (FA) in periodontitis.
Wang Q, Feng B, Gao Y.
europepmc   +2 more sources

Identification and differentiation of major components in three different “Sheng-ma” crude drug species by UPLC/Q-TOF-MS

open access: yesActa Pharmaceutica Sinica B, 2017
Cimicifugae Rhizoma (Sheng ma) is a Ranunculaceae herb belonging to a composite family and well known in China. has been widely used in traditional Chinese medicine. The Pharmacopoeia of the People׳s Republic of China contains three varieties (Cimicifuga
Mengxue Fan   +5 more
doaj   +1 more source

Suppression of Release of Matrix Metalloprotease-1 from Human Gingival Fibroblasts by Rhizome Extract and a Novel Cimigenol Xyloside as an Active Constituent

open access: yesNatural Product Communications, 2018
Oral malodor has become a major oral problem and the need for self-medication has increased. Oral malodor is attributed to the various enzymes produced by periodontal bacteria and the treatment of periodontal disease is recognized as the major therapy ...
Mami Honda-Yokota   +3 more
doaj   +1 more source

Der kontrollierte Anbau von Actea racemosa (L.)

open access: yesJulius-Kühn-Archiv, 2023
Im Jahr 2006 starteten bei VitaPlant für die Mutterfirma Max Zeller Söhne die Arbeiten an der Entwicklung einer nachhaltigen Produktion von Wurzeldroge von Actea racemosa (syn. Cimicifuga racemosa).
Chaanin, Amin
doaj   +1 more source

The results of the research on cimicifuga extract impact in systematic and local use on structural and functional skin rates in perimenopause, menopause and postmenopause [PDF]

open access: yesГинекология, 2015
Results of studying of efficiency and safety of the combination of medicine Ci-Clim and cosmetic product Ci-Clim (JSC EVALAR, Russia), containing extract of cimicifuga racemosa, for the purpose of correction of structural and functional changes of skin ...
Ya A Yutskovskaya, A S Sukhanova
doaj  

Antioxidant activity and mechanism of Rhizoma Cimicifugae [PDF]

open access: yesChemistry Central Journal, 2012
As a typical Chinese herbal medicine, rhizoma Cimicifugae (RC, in Chinese) possesses various pharmacological effects involved in antioxidant activity. However, its antioxidant activity has not been reported so far. The aim of the present study was to systematically evaluate the antioxidant ability of RC in vitro, then discuss the mechanism.Firstly ...
Li Xican   +4 more
openaire   +3 more sources

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

open access: yesCancer Nexus, Volume 2, Issue 3, July 2026.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang   +4 more
wiley   +1 more source

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