Results 41 to 50 of about 2,262 (206)

A Systematic Review on Functional Bioactive Compound Atractylone: Natural Source, Pharmacological Properties and Mechanisms Insights

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Atractylone exhibits diverse pharmacological effects, including anticancer and neuroprotection. A systematic review was conducted following PRISMA guidelines to analyze Atractylone. This study explores Atractylone's sources, biosynthesis, and therapeutic potential.
Hamza Elhrech   +8 more
wiley   +1 more source

Differences in the flower visitor behaviour on female and hermaphroditic flowers of Cimicifuga simplex

open access: yes, 2021
Toji, Tsubasa, Itino, Takao (2021): Differences in the flower visitor behaviour on female and hermaphroditic flowers of Cimicifuga simplex. Journal of Natural History 55 (19-20): 1289-1298, DOI: 10.1080/00222933.2021.1946611, URL: http://dx.doi.org/10 ...
Toji, Tsubasa, Itino, Takao
core   +1 more source

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

open access: yesAdvanced Science, Volume 12, Issue 43, November 20, 2025.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo   +7 more
wiley   +1 more source

Il ritorno della Cimicifuga racemosa [PDF]

open access: yes, 2008
La Cimicifuga racemosa (Black cohosh) è erba medicinale usata tradizionalmente presso le popolazioni indiane del Nord America, nota sin dagli inizi del 1800 per i suoi effetti benefici sui sintomi menopausali.
Pansini, Francesco Saverio
core  

Ferulic acid: extraction, estimation, bioactivity and applications for human health and food

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 8, Page 4168-4177, June 2025.
Abstract Ferulic acid ((E)‐3‐(4‐hydroxy‐3‐methoxy‐phenyl) prop‐2‐enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of therapeutic effects, including anti‐inflammatory, antimicrobial, anticancer, antidiabetic, cardiovascular and neuroprotective
Mukul Kumar   +13 more
wiley   +1 more source

Cytotoxic Cycloartane Triterpenoid Saponins from the Rhizomes of Cimicifuga foetida

open access: yesNatural Products and Bioprospecting, 2019
To enrich the bioactive cycloartane triterpenoid glycoside named actein and find out more cytotoxic cycloartane triterpenes, a phytochemical study of Cimicifuga foetida was conducted.
Jing Lu   +4 more
doaj   +1 more source

Machine Learning-Based Analysis Reveals Triterpene Saponins and Their Aglycones in Cimicifuga racemosa as Critical Mediators of AMPK Activation. [PDF]

open access: yesPharmaceutics
Cimicifuga racemosa (CR) extracts contain diverse constituents such as saponins. These saponins, which act as a defense against herbivores and pathogens also show promise in treating human conditions such as heart failure, pain, hypercholesterolemia ...
Drewe J   +4 more
europepmc   +3 more sources

Part 2: Drug Interactions Involving Cannabis Products in Persons Aged 18 and Over: A Summary of Published Case Reports and Analysis of the FDA Adverse Event Reporting System

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 1, February 2025.
ABSTRACT The increasing utilization of cannabis products combined with lack of data regarding potential cannabis–prescription drug interactions is concerning. This study aimed to review published case reports and FDA Adverse Event Reporting System (FAERS) spontaneous reports to assess cannabis–drug interactions in persons aged 18 and over. A literature
Maryann R. Chapin   +7 more
wiley   +1 more source

Phenolic Constituents of the Aerial Parts of Cimicifuga simplex and Cimicifuga japonica

open access: yes, 2016
Chemical investigation of the aerial parts of Cimicifuga simplex afforded four new fukinolic acid analogues, cimicifugic acids K−N (1−4), and 10 known compounds, and C.
Atsufumi Iwanaga (2303770)   +3 more
core   +1 more source

Administration of isoferulic acid improved the survival rate of lethal influenza virus pneumonia in mice

open access: yesMediators of Inflammation, 2001
Background: Isoferulic acid (IFA) is a main active ingredient of the rhizoma of Cimicifuga heracleifolia, which is used frequently in Japanese traditional medicine as an anti-inflammatory drug.
Shinya Sakai   +5 more
doaj   +1 more source

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