Results 41 to 50 of about 2,413 (162)

Cytotoxic Cycloartane Triterpenoid Saponins from the Rhizomes of Cimicifuga foetida

Natural Products and Bioprospecting, 2019
To enrich the bioactive cycloartane triterpenoid glycoside named actein and find out more cytotoxic cycloartane triterpenes, a phytochemical study of Cimicifuga foetida was conducted.
Jing Lu, Xing-Rong Peng, Da-Shan Li, Qiang-Qiang Shi, Ming-Hua Qiu   +4 more
doaj   +1 more source

Wenyang Decoction Ameliorates DSS‐Induced Ulcerative Colitis by Regulating Macrophage Polarization and the PI3K/AKT/mTOR/HIF‐1α Signaling Pathway

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Aim Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by intestinal inflammation and epithelial damage. This study aims to investigate the therapeutic effects of Wenyang decoction (WYD) in a dextran sulfate sodium (DSS)‐induced UC model and its underlying mechanisms, with a focus on macrophage polarization and the regulation
Shengwei Li, Guanghui Yuan, Chan Chen, Jihong Lu, Xing Zhang, Oscar Medina-Contreras   +5 more
wiley   +1 more source

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

Advanced Science, Volume 12, Issue 43, November 20, 2025.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo, Qiancheng Mao, Xinyu Fang, Liuxuan Huang, Haoquan Tian, Wenguang Yang, Feiyue Zhou, Ke Ma   +7 more
wiley   +1 more source

Administration of isoferulic acid improved the survival rate of lethal influenza virus pneumonia in mice

Mediators of Inflammation, 2001
Background: Isoferulic acid (IFA) is a main active ingredient of the rhizoma of Cimicifuga heracleifolia, which is used frequently in Japanese traditional medicine as an anti-inflammatory drug.
Shinya Sakai, Hiroshi Ochiai, Naoki Mantani, Toshiaki Kogure, Naotoshi Shibahara, Katsutoshi Terasawa   +5 more
doaj   +1 more source

Cimicifuga racemosa (Cultivated)

, 2011
Cimicifuga racemosa, inflorescence. Family Ranunculaceae, Subclass Magnoliidae.
James R. Manhart
core   +1 more source

Ferulic acid: extraction, estimation, bioactivity and applications for human health and food

Journal of the Science of Food and Agriculture, Volume 105, Issue 8, Page 4168-4177, June 2025.
Abstract Ferulic acid ((E)‐3‐(4‐hydroxy‐3‐methoxy‐phenyl) prop‐2‐enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of therapeutic effects, including anti‐inflammatory, antimicrobial, anticancer, antidiabetic, cardiovascular and neuroprotective
Mukul Kumar, Deepika Kaushik, Shubham Shubham, Ashwani Kumar, Vishal Kumar, Emel Oz, Charles Brennan, Maomao Zeng, Charalampos Proestos, Kenan Çadırcı, Muharrem Bayrak, Tahra Elobeid, Sercan Karav, Fatih Oz   +13 more
wiley   +1 more source

Phytocombinations as a way to comfort: non-hormonal support for women in perimenopause

Репродуктивная эндокринология
Objective of the study: To compare a multicomponent herbal supplement Lifemin® Intense (multicomponent phytocomplex concluded Cimicifuga racemosa, Humulus lupulus, Pueraria lobata, Dioscorea villosa, Angelica sinensis, and Crocus sativus) with a ...
S.O. Shurpyak, V.I. Pyrohova
doaj   +1 more source

Part 2: Drug Interactions Involving Cannabis Products in Persons Aged 18 and Over: A Summary of Published Case Reports and Analysis of the FDA Adverse Event Reporting System

Pharmacology Research &Perspectives, Volume 13, Issue 1, February 2025.
ABSTRACT The increasing utilization of cannabis products combined with lack of data regarding potential cannabis–prescription drug interactions is concerning. This study aimed to review published case reports and FDA Adverse Event Reporting System (FAERS) spontaneous reports to assess cannabis–drug interactions in persons aged 18 and over. A literature
Maryann R. Chapin, Sandra L. Kane‐Gill, Xiaotong Li, Kojo Abanyie, Sanya B. Taneja, Susan Egbert, Mary F. Paine, Richard D. Boyce   +7 more
wiley   +1 more source

Differences in the flower visitor behaviour on female and hermaphroditic flowers of Cimicifuga simplex

, 2021
Toji, Tsubasa, Itino, Takao (2021): Differences in the flower visitor behaviour on female and hermaphroditic flowers of Cimicifuga simplex. Journal of Natural History 55 (19-20): 1289-1298, DOI: 10.1080/00222933.2021.1946611, URL: http://dx.doi.org/10 ...
Toji, Tsubasa, Itino, Takao
core   +1 more source

New Triterpene Diglycosides from the Rhizome of Cimifuga foetida

Molecules, 2008
Five new 9,19-cycloartane triterpene diglycosides, which have been named cimiaceroside C (1), and cimifosides A-D (2-5) together with the known compounds cimiracemoside D (6), cimidahurine (7) and α-D-glucopyranosyl-l-β-D-fructofuranoside (8) were ...
Minghua Qiu, Hongjie Zhang, Lin Zhou, Yin Nian, Jian Yan, Lirong Sun   +5 more
doaj   +1 more source