Results 51 to 60 of about 15,309 (149)
Prediction of conserved precursors of miRNAs and their mature forms by integrating position-specific structural features. [PDF]
PLoS ONE, 2012 MicroRNA (miRNA) precursor hairpins have a unique secondary structure, nucleotide length, and nucleotide content that are in most cases evolutionarily conserved. The aim of this study was to utilize position-specific features of miRNA hairpins to improve
Goro Terai +3 more
doaj +1 more source
The Embryonic Development of the Cotylean Polyclad Phrikoceros jannetae
Acta Zoologica, EarlyView.ABSTRACT Polyclads exhibit distinct developmental modes ranging from direct to indirect development, with several transitional stages also recognised. The existence of an indirect developmental mode in polyclads with a planktonic life history stage in the form of a free‐swimming larva is unique among all free‐living flatworms and makes polyclads a ...
Mehrez Gammoudi +6 more
wiley +1 more source
The FEBS Journal, EarlyView.Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal +5 more
wiley +1 more source
, 2014 International audienceProgrammed cell death (PCD) is a mechanism implicated in many physiological and pathological processes. Until recently, apoptosis (self-killing) was the most largely studied mechanism of PCD but a growing number of laboratories are ...
Godefroy, Nelly +7 more
core +1 more source
Thyroid-like function in the urochordate Ciona intestinalis [PDF]
, 2011 In the studies reported in the manuscript I investigated the involvement of Iodine and thyroxine (Thyroid Hormone, T4) in Ciona intestinalis metamorphosis. To date, the mechanisms regulating the metamorphosis of ascidians remain largely unknown.
Staiano, Leopoldo
core +1 more source
Defining the role of αC helix interactions in the activation of the integrin αI domain
The FEBS Journal, EarlyView.The α2I domain of the α2β1 integrin contains a distinctive αC helix and a conserved Arg288‐Glu318 ion pair that stabilizes the closed state of the domain. Disruption of this ion pair in the activated α2I variant unwinds the αC helix, which allows interaction with additional collagen‐binding sites increasing collagen binding.
Liisa Pösö +7 more
wiley +1 more source
Phylogenomics of vertebrate serpins [PDF]
, 2010 Kumar A. Phylogenomics of vertebrate serpins. Bielefeld (Germany): Bielefeld University; 2010.The serpins constitute a superfamily of proteins that fold into a conserved tertiary structure and employ a sophisticated, irreversible suicide-mechanism of ...
Kumar, Abhishek
core
Effects of tributyltin chloride in ascidian embryos: modulation of kinase-mediated signalling pathways [PDF]
Invertebrate Survival Journal, 2009 We studied the effects of various TBT concentrations by assaying the activity of ERK 1/2 (p44/42) and phospho-ERK1/2 (phospho-p44/42), proteins with a key role in ascidian development, and tyrosine kinase-dependent pathway. The effects of this xenobiotic
F Damiani, M Gianguzza, G Dolcemascolo
doaj +1 more source
The Greenland–Scotland Ridge in a Changing Ocean: Time to Act?
Marine Ecology, EarlyView.ABSTRACT The Greenland–Scotland Ridge is a submarine mountain that rises up to 500 m below the sea surface and extends from the east coast of Greenland to the continental shelf of Iceland and across the Faroe Islands to Scotland. The ridge not only separates deeper ocean basins on either side, that is, the North Atlantic and Arctic oceans, but also ...
Christophe Pampoulie +2 more
wiley +1 more source
Huntingtin gene evolution in Chordata and its peculiar features in the ascidian
BMC Genomics, 2006 Background To gain insight into the evolutionary features of the huntingtin (htt) gene in Chordata, we have sequenced and characterized the full-length htt mRNA in the ascidian Ciona intestinalis, a basal chordate emerging as new invertebrate model ...
Cattaneo Elena +3 more
doaj +1 more source