Results 171 to 180 of about 55,909 (247)

Dissemination of Class 1, 2, and 3 Integrons Among Multidrug‐Resistant Isolates of Pseudomonas aeruginosa

MicrobiologyOpen, Volume 15, Issue 6, December 2026.
Clinical Pseudomonas aeruginosa isolates showed widespread Class 1 and 2 integrons carrying diverse resistance‐associated gene cassettes, including aadB, blaOXA10‐aac(6′)‐II, and aadB‐blaOXA10‐aac(6′)‐Ib, which were strongly associated with antibiotic resistance phenotypes, highlighting the need for enhanced surveillance and targeted infection‐control ...
Mahdi Hosseini Bafghi, Abbas Baghaie, Razieh Nazari   +2 more
wiley   +1 more source

In‐Vitro Activity of Ceftazidime‐Avibactam and Comparator Agents Against Carbapenem‐Resistant Gram‐Negative Isolates at a Tertiary Care Hospital in Lahore, Pakistan: A Cross‐Sectional Study

MicrobiologyOpen, Volume 15, Issue 6, December 2026.
Of 210 consecutive non‐duplicate carbapenem‐resistant Gram‐negative isolates collected at a tertiary care hospital in Lahore, Pakistan (December 2024–May 2025), 200 had a ceftazidime‐avibactam (CAZ–AVI) result; 70.5% were susceptible (141/200; 95% CI 63.7–76.7). Susceptibility varied by sample source (p = 0.008), being highest in blood cultures (81.2%),
Faryal Yunus, Obaid Ur Rehman, Muhammad Murtaza, Safa Mazhar, Abedin Samadi, Ahmed Asad Raza   +5 more
wiley   +1 more source

Influence of the Nature of the Cationic Residues on the Activity of the Antimicrobial Peptides of the Lynronne Family

Journal of Peptide Science, Volume 32, Issue 12, December 2026.
Derivatives of Lynronnes with cationic residues substitution were designed and tested in terms of antimicrobial activity, anti‐biofilm activity, mechanism of action, and in vitro toxicity. Lys‐substitution emerges as a promising strategy for improved activity and selectivity, particularly against E. coli. ABSTRACT Most antimicrobial peptides (AMPs) are
Alexis Reinbold, Maxime Gâchon, Jean‐François Cavalier, Laure Genet, Sophie Guillier, Mathilde Lescat, Muriel Serradeil‐Albalat, Linda B. Oyama, Cendrine Nicoletti, Sharon A. Huws, Nicolas Vidal, Fabiano Cavalcanti Fernandes, Andreia Gomes Martins, Stéphane Canaan, Octávio Luiz Franco, Sophie Tronnet, Olga Iranzo, Marc Maresca   +17 more
wiley   +1 more source

Comparison of Machine Learning Classifiers for Predicting Reported Antibiotic Treatment After Recent Fever/Cough Among Under‐Five Children: A Pooled Analysis of DHS Data From 64 LMICs

Public Health Challenges, Volume 5, Issue 4, December 2026.
Using pooled Demographic and Health Survey data from 64 LMICs, six machine learning and logistic regression models showed only modest ability to predict caregiver‐reported antibiotic treatment after childhood fever or cough. No model performed best across all metrics, supporting cautious interpretation and further external validation.
Md Sabbir Hossain, Prosenjit Basak Arka, Md Fakrul Islam, Mahfuzer Rohman, Md Jamal Uddin   +4 more
wiley   +1 more source

From Agro‐Industrial Waste to Functional Packaging Using Antimicrobial and Mechanically Reinforced Starch Foams With Melon Seed and Rosemary

Journal of Applied Polymer Science, Volume 143, Issue 43, November 15, 2026.
Agro‐industrial waste was upcycled into biodegradable starch foams reinforced with melon seed and rosemary flours, yielding sustainable food packaging with enhanced mechanical performance, selective antimicrobial activity, and rapid biodegradation. ABSTRACT The demand for sustainable alternatives to petroleum‐based packaging has promoted starch‐based ...
Ana Carolina Agne Ferreira Zão, Naiara Jacinta Clerici, Flávio Fonseca Veras, Cecília Roratto Köhn, Adriano Brandelli, Juliane Elisa Welke, Patrícia Benelli, Alessandro de Oliveira Rios, Simone Hickmann Flôres   +8 more
wiley   +1 more source

Fundamentals, Advances, and Applications of Electrospun Nanofibrous 3D Materials

Journal of Applied Polymer Science, Volume 143, Issue 43, November 15, 2026.
Three‐dimensional electrospun nanofibrous systems offer unique properties and microenvironments. These properties are determined by the fabrication strategies employed and can be adjusted by the incorporation of functional additives to achieve multifunctionality for specific applications. The applications range from the biomedical to the environmental,
Rebecca Hengsbach, Viraj P. Nirwan, Altangerel Amarjargal, Zahra Asefi, Amir Fahmi   +4 more
wiley   +1 more source

Stimuli‐Responsive Lipid‐Based Nanocarriers for Antimicrobial Therapy

Advanced Therapeutics, Volume 9, Issue 11, November 2026.
This manuscript demonstrated, through a scoping review of the literature, that modifying lipid nanocarriers with organic and inorganic excipients is a promising alternative to increase in vitro drug release of antimicrobial compounds under the studied stimulus and significantly enhance in vitro and in vivo antimicrobial activity compared to isolated ...
Brenda Maria Silva Bezerra, Adrian Lima Roberto, Luiz Gustavo Girão Lima, Mariana Rillo Sato, Leila Aparecida Chiavacci, João Augusto Oshiro‐Junior   +5 more
wiley   +1 more source

Development of Novel Furan–Chalcone Derivatives as Targeting Bacterial DNA Gyrase and Topoisomerase IV: Design, Synthesis, and In Silico Studies

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Furan–chalcone derivatives (Na1–Na8) were successfully designed, synthesized, and biologically evaluated using integrated experimental and computational approaches. ABSTRACT A series of novel furan–chalcone derivatives (Na1–Na8) were synthesized and evaluated for their antimicrobial, antioxidant, DNA gyrase inhibitory, and computational properties ...
Nagaraj N Durgadasheemi, Vishal CS
wiley   +1 more source

Chitosan‐Based Hydrogels for Periodontal Therapy: From Drug‐Polymer Chemistry to Smart Multifunctional and Regenerative Systems

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Chitosan‐based hydrogels are evolving from simple local drug carriers into multifunctional periodontal platforms that integrate antimicrobial, anti‐inflammatory, antioxidant, and regenerative functions. Chemical crosslinking, nanocomposite design, and stimulus‐responsive architectures enable adaptive therapeutic delivery.
Vikesh Kumar, B. T. Nandish, Sowmya Rao, Manojna K. M.   +3 more
wiley   +1 more source

Phytochemical Screening, Pharmacological Evaluation, and Exploratory In Silico Analysis of Emilia sonchifolia Extract and Solvent Fractions

Cell Biochemistry and Function, Volume 44, Issue 11, November 2026.
ABSTRACT Emilia sonchifolia (L.) DC. is a medicinal plant used traditionally for the management of several disorders; however, integrated experimental evaluation of its pharmacological properties remains limited. This study evaluated the phytochemical composition and selected biological activities of the methanolic whole‐plant extract of E. sonchifolia
Md. Masud Morshed, Mohammad Arman, Mohammad Nazmul Islam, Ziaul Karim, Rakibur Rahman, Mohammed Hassan Kawsar, Md. Sohel Rana   +6 more
wiley   +1 more source