Results 221 to 230 of about 376,159 (303)

Liver clock: Malalignment and entrainment therapeutics. [PDF]

World J Gastrointest Pharmacol Ther
Sharma S, Pandey S, Mishra AK.
europepmc   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño, Rashmi Mehta, Andrea Ribeiro de Souza, Jon Collins, Brandon Swift   +4 more
wiley   +1 more source

Bright Light Therapy in Psychiatric Disorders: Mechanisms, Clinical Procedures and Evidence. [PDF]

Life (Basel)
Pardossi S, Bossini L, Milani V, Rescalli MB, Cuomo A.   +4 more
europepmc   +1 more source

Cameras do not always take a full picture: wolf activity patterns revealed by accelerometers versus road‐positioned camera traps

Remote Sensing in Ecology and Conservation, EarlyView.
Camera traps have become an increasingly popular non‐invasive alternative to animal‐attached devices for studying wildlife behaviour. This study compared wolf (Canis lupus) activity patterns derived from collar accelerometers and road‐positioned camera traps and revealed strong overall agreement but also important seasonal and diel mismatches between ...
Katarzyna Bojarska, Michał Żmihorski, Morteza Naderi, J. David Blount, Mark Chynoweth, Emrah Coban, Çağan H. Şekercioğlu, Josip Kusak   +7 more
wiley   +1 more source

Effects of the signaling molecule cyclic-di-GMP on cyanobacterial circadian rhythm in <i>Synechococcus elongatus</i> PCC 7942. [PDF]

J Bacteriol
Yamaguchi CC, Kanaly RA, Nishizaki E, Yamashita K, Takatsuki K, Furuike Y, Fang M, Akiyama S, Aoki S, Tsukamoto M, Nakahira Y, Golden SS, Kutsuna S.   +12 more
europepmc   +1 more source

The impact of regional, seasonal, and environmental factors on the sleep status of urban residents in China

Sleep Research, EarlyView.
Abstract Background Sleep quality is influenced by various environmental factors, yet their impact across different regions and seasons in China remains understudied. Objective This study evaluated how environmental factors affect sleep quality, duration, and disorders among Chinese urban residents in different regions and seasons.
Youyang Qu, Shuhan Meng, Wanqiao Qi, Guihai Chen, Zan Wang, Jinzhu Yan, Ping Gu, Yanmei Zhu, Zifen Wan, Li Wang, Yuanqing Wang, Zhongming He, Dali Li, Lisan Zhang, Yunhui Lv, Guohui Li, Weimin Qu, Lili Long, Weiping Liu, Ning Li, Jianbin Liu, Wei Wu, Xiaojiang Jiang, Liang Xie, Liying Deng, Xiang Gao, Zhili Huang, Yulan Zhu   +27 more
wiley   +1 more source

Effects of sodium chloride on circadian period and temperature compensation of KaiC phosphorylation. [PDF]

Sci Rep
Kim E, Adams M, Tyree S, Kim Y.
europepmc   +1 more source

Association of insomnia, insulin resistance traits, and cardiovascular disease risk: A two‐step Mendelian randomization study

Sleep Research, EarlyView.
The causal roles of metabolic traits in mediating the effects of insomnia on CVDs. CAD, coronary artery disease; HbA1c, hemoglobin A1c; HDL‐C, high‐density lipoprotein cholesterol; IR, insulin resistance; MI, myocardial infarction; TG, triglyceride; T2DM, type 2 diabetes.
Binhe Yu, Yanmin Xu, Xiaoyu Wang, Shuo Ye, Ruixiang Cui, Yujing Sun, Meng Li, Yan Li, Wenhui Yuan, Sheng Guo, Zhigang Chen, Xiaohong Kang, Sizhi Ai   +12 more
wiley   +1 more source

Exploring sleep health and circadian rhythm disruption in Sjögren's disease: an accelerometric and self-reported cross-sectional study. [PDF]

Rheumatology (Oxford)
Di Pede C, Colitta A, Bruno S, Frumento P, Maestri Tassoni M, Fulvio G, La Rocca G, Bonanni E, Mosca M, Talarico R, Baldini C, Faraguna U.   +11 more
europepmc   +1 more source

Bile acid metabolism and sleep: Mechanistic interplay and clinical implications of the gut–liver–brain axis

Sleep Research, EarlyView.
Abstract The bidirectional interplay between sleep and metabolic homeostasis is fundamental to physiological health. While the roles of glucose and lipid metabolism in sleep regulation have been extensively characterized, bile acids (BAs), which are traditionally viewed as digestive surfactants, are emerging as critical metabolic messengers with ...
Yu Jiang, Shuangyan Li, Dhirendra Paudel, Miaoqin Tan, Bin Zhang   +4 more
wiley   +1 more source