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Circadian biomarkers, circadian genes and bipolar disorders
Journal of Physiology-Paris, 2011Bipolar disorders are associated with circadian deregulations both during acute mood episodes and during euthymic periods, suggesting that these circadian rhythms may represent trait markers of the disease. Several arguments demonstrate that deregulations of circadian rhythms may be part of the pathophysiology of bipolar disorders.
Vanessa, Milhiet +3 more
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The American Journal of Medicine, 1988
All forms of life, from the simplest cells to the most complex organisms, show periodicity in some of their biologic activities and functions. The most common of these rhythmic events are those that we refer to as "circadian" (circa, around; dias, day).
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All forms of life, from the simplest cells to the most complex organisms, show periodicity in some of their biologic activities and functions. The most common of these rhythmic events are those that we refer to as "circadian" (circa, around; dias, day).
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Circadian transcription in liver
Biosystems, 2010Circadian rhythms regulate a wide range of cellular, physiological, metabolic and behavioral activities in mammals. The complexity of tissue- and day-time specific regulation of thousands of clock controlled genes (CCGs) suggests that many transcriptional regulators are involved.
K. Bozek +4 more
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A role of the circadian system and circadian proteins in aging
Ageing Research Reviews, 2007Circadian rhythms are genetically determined biological rhythms that are considered an important adaptive mechanism to the cyclical light/dark alterations in the Earth environment. Age-related changes in the circadian time-keeping mechanism are well known, and seemingly contribute to various pathologies of aging.
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COVID-19 management in light of the circadian clock
Nature Reviews Molecular Cell Biology, 2020Sandipan Ray +2 more
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