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A Review of Evidence for the Involvement of the Circadian Clock Genes into Malignant Transformation of Thyroid Tissue [PDF]
Clocks & Sleep, 2023 (1) Background: In 2013, the results of a pioneer study on abnormalities in the levels and circadian rhythmicity of expression of circadian clock genes in cancerous thyroid nodules was published.
Arcady A. Putilov +2 more
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Research progress on the mutual regulatory mechanism of circadian clock genes and autophagy [PDF]
Frontiers in Cell and Developmental BiologyRecent studies have highlighted the intricate relationship between the circadian rhythm, a natural biological process responsive to light and darkness, and autophagy, a mechanism crucial for maintaining cellular homeostasis.
Yueqi Ma +17 more
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Feeding period restriction alters the expression of peripheral circadian rhythm genes without changing body weight in mice. [PDF]
PLoS ONE, 2012 Accumulating evidence suggests that the circadian clock is closely associated with metabolic regulation. However, whether an impaired circadian clock is a direct cause of metabolic dysregulation such as body weight gain is not clearly understood. In this
Hagoon Jang +5 more
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Diurnal oscillations of soybean circadian clock and drought responsive genes. [PDF]
PLoS ONE, 2014 Rhythms produced by the endogenous circadian clock play a critical role in allowing plants to respond and adapt to the environment. While there is a well-established regulatory link between the circadian clock and responses to abiotic stress in model ...
Juliana Marcolino-Gomes +9 more
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Plants, 2023 The circadian clock, an endogenous timing system, exists in nearly all organisms on Earth. The plant circadian clock has been found to be intricately linked with various essential biological activities. Extensive studies of the plant circadian clock have
Xingwei Wang, Yanfei Hu, Wei Wang
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Non-circadian expression masking clock-driven weak transcription rhythms in U2OS cells. [PDF]
PLoS ONE, 2014 U2OS cells harbor a circadian clock but express only a few rhythmic genes in constant conditions. We identified 3040 binding sites of the circadian regulators BMAL1, CLOCK and CRY1 in the U2OS genome. Most binding sites even in promoters do not correlate
Julia Hoffmann +5 more
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Role of Sleep Restriction in Daily Rhythms of Expression of Hypothalamic Core Clock Genes in Mice
Current Issues in Molecular Biology, 2022 Lack of sleep time is a menace to modern people, and it leads to chronic diseases and mental illnesses. Circadian processes control sleep, but little is known about how sleep affects the circadian system.
Weitian Li +4 more
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Circadian clock genes, ovarian development and diapause [PDF]
BMC Biology, 2010 Insects, like most organisms, have an internal circadian clock that oscillates with a daily rhythmicity, and a timing mechanism that mediates seasonal events, including diapause. In research published in BMC Biology, Ikeno et al. show that downregulation of the circadian clock genes period and cycle affects expression of ovarian diapause in the insect ...
Bradshaw William E +1 more
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Membrane Currents, Gene Expression, and Circadian Clocks [PDF]
Cold Spring Harbor Perspectives in Biology, 2017 Neuronal circadian oscillators in the mammalian and Drosophila brain express a circadian clock comprised of interlocking gene transcription feedback loops. The genetic clock regulates the membrane electrical activity by poorly understood signaling pathways to generate a circadian pattern of action potential firing.
Allen, Charles N +2 more
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Cells, 2021 The circadian clock drives time-specific gene expression, enabling biological processes to be temporally controlled. Plants that conduct crassulacean acid metabolism (CAM) photosynthesis represent an interesting case of circadian regulation of gene ...
Robert C. Moseley +4 more
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