Results 181 to 190 of about 67,567 (286)

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

Genetic and environmental influences on sleep quality, ability to settle, and crying duration in 2‐ and 5‐month‐old infants: A longitudinal twin study

JCPP Advances, EarlyView.
This study found that genetic factors largely influence crying duration and settle ability in infancy, while shared environmental factors primarily affect the number of night wakeups. Etiological influences tended to change from 2 to 5 months, reflecting a highly plastic period in infant brain development and in child‐environment interactions. Abstract
Charlotte Viktorsson, Ashraf Yahia, Mark J. Taylor, Angelica Ronald, Kristiina Tammimies, Terje Falck‐Ytter   +5 more
wiley   +1 more source

Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review). [PDF]

Mol Med Rep
Wang J, Cao M, Li S, Pei W, Li J, Wang Z.   +5 more
europepmc   +1 more source

Circadian Clock Genes Are Correlated with Prognosis and Immune Cell Infiltration in Colon Adenocarcinoma. [PDF]

Comput Math Methods Med, 2022
He A, Huang Z, Zhang R, Lu H, Wang J, Cao J, Feng Q.   +6 more
europepmc   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista, Patrizia Ventura, Samuele Cortese, Paolo Trerotoli, Alessandra Di Gioia, Lucia Margari   +5 more
wiley   +1 more source

Avian circadian clock genes: ontogeny and role for adaptive programming in avian embryos. [PDF]

Front Physiol
Wellard CJ, Weger M, Gachon F, Buchanan KL.   +3 more
europepmc   +1 more source

Drivers of phenotypic variation in cartilage: Circadian clock genes. [PDF]

J Cell Mol Med, 2021
Song X, Bai H, Meng X, Xiao J, Gao L.
europepmc   +1 more source

Peri‐implant hypoxia as a potential barrier against ferroptotic mechanisms during peri‐implant diseases: A cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background Hypoxia modulates inflammation and oxidative stress through hypoxia‐inducible factor‐1α (HIF‐1α). Ferroptosis, an iron‐dependent cell death process, is regulated by glutathione peroxidase‐4 (GPX4) and involves lipid peroxidation markers like malondialdehyde (MDA).
Büşra Yılmaz, Ali Gürkan, Beral Afacan, Harika Atmaca, Timur Köse, Gülnur Emingil   +5 more
wiley   +1 more source

Regulation of testosterone synthesis by circadian clock genes and its research progress in male diseases. [PDF]

Asian J Androl
Ning G, Li BN, Wu H, Shi RB, Peng AJ, Wang HY, Zhou X.   +6 more
europepmc   +1 more source