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Circadian clocks - from genes to complex behaviour [PDF]
Reproduction Nutrition Development, 1999 Circadian clocks control temporal structure in practically all organisms and on all levels of biology, from gene expression to complex behaviour and cognition. Over the last decades, research has begun to unravel the physiological and, more recently, molecular mechanisms that underlie this endogenous temporal programme.
Roenneberg, Till, Merrow, Martha
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Circadian Rhythms in the CNS and Peripheral Clock Disorders: The Circadian Clock and Hyperlipidemia
Journal of Pharmacological Sciences, 2007 A circadian clock controls various physiological and behavioral rhythms. In mammals, a master circadian clock exists in the suprachiasmatic nucleus of the hypothalamus, and slave oscillators can be found in most tissues.
Takashi Kudo +2 more
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Bipolar Disorder, Circadian Rhythm and Clock Genes
Clinical Psychopharmacology and Neuroscience, 2023 Sleep disturbance and abnormal circadian rhythm might be closely related to bipolar disorder. Several studies involving disturbed sleep/wake cycle, changes in rhythms such as melatonin and cortisol, clock genes, and circadian preference have shown the relationship between bipolar disorder and circadian rhythm.
Junsoo Chung +2 more
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Biologia Plantarum, 2018 Strawberry is an economically important fruit crop worldwide. Circadian clock genes are endogenous timers that regulate a wide range of metabolic processes and consequently plant development.
X. D. Chen, J. Wang, M. Z. Zhao, F. Zhao
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Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain
Frontiers in Physiology, 2021 To better understand the complexity of clock genes in salmonids, a taxon with an additional whole genome duplication, an analysis was performed to identify and classify gene family members (clock, arntl, period, cryptochrome, nr1d, ror, and csnk1).
Charlotte M. Bolton +4 more
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Opposite Carcinogenic Effects of Circadian Clock Gene BMAL1 [PDF]
Scientific Reports, 2018 AbstractThe circadian clock confers daily rhythmicity on many biochemical and physiological functions and its disruption is associated with increased risks of developing obesity, diabetes, heart disease and cancer. Although, there are studies on the role of Bmal1 in carcinogenesis using germline, conditional or tissue-specific knockouts, it is still ...
Tuba Korkmaz +6 more
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Parallel analysis of Arabidopsis circadian clock mutants reveals different scales of transcriptome and proteome regulation [PDF]
Open Biology, 2017 The circadian clock regulates physiological processes central to growth and survival. To date, most plant circadian clock studies have relied on diurnal transcriptome changes to elucidate molecular connections between the circadian clock and observable ...
Alexander Graf +6 more
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Direct Repression of Evening Genes by CIRCADIAN CLOCK-ASSOCIATED1 in the Arabidopsis Circadian Clock [PDF]
The Plant Cell, 2016 The circadian clock is a biological timekeeping system that provides organisms with the ability to adapt to day-night cycles. Timing of the expression of four members of the Arabidopsis thaliana PSEUDO-RESPONSE REGULATOR(PRR) family is crucial for proper clock function, and transcriptional control of PRRs remains incompletely defined.
Mari Kamioka +6 more
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Journal of Pharmacological Sciences, 2007 The cardiovascular diseases are closely related to circadian rhythm, which is under the control of the biological clock. Clock genes show circadian oscillation not only in the suprachiasmatic nucleus but also in peripheral tissues, suggesting the ...
Koji Maemura +2 more
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An Overview of the Polymorphisms of Circadian Genes Associated With Endocrine Cancer
Frontiers in Endocrinology, 2019 A major consequence of the world industrialized lifestyle is the increasing period of unnatural light in environments during the day and artificial lighting at night.
Sonia Morales-Santana +6 more
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