Results 241 to 250 of about 67,567 (286)

Mutations of the circadian clock genes <i>Cry</i>, <i>Per,</i> or <i>Bmal1</i> have different effects on the transcribed and nontranscribed strands of cycling genes. [PDF]

Proc Natl Acad Sci U S A
Yang Y, Wu G, Sancar A, Hogenesch JB.
europepmc   +1 more source

Gestational Melatonin Supplementation Attenuates Maternal Sleep Deprivation‐Induced Steatohepatitis Susceptibility in Offspring

Cell Proliferation, EarlyView.
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo, Zexin Yang, Junsen She, Chen Fang, Yizhi Hu, Hefeng Huang, Ling Gao   +6 more
wiley   +1 more source

Cartilage-specific knockout of miRNA-128a expression normalizes the expression of circadian clock genes (CCGs) and mitigates the severity of osteoarthritis. [PDF]

Biomed J
Ko JY, Wang FS, Lian WS, Fang HC, Kuo SJ.   +4 more
europepmc   +1 more source

p75NTR Promotes Circadian‐Driven Mineralization During Tooth Development via CK2/PER2 Pathway

Cell Proliferation, EarlyView.
The diagram illustrates how the circadian rhythm regulates the p75NTR‐CK2‐PER2 axis, driving rhythmic biomineralisation during tooth development. ABSTRACT Circadian rhythm is an essential biological process that synchronises physiological activities with environmental light/dark cycles.
Manzhu Zhao, Hongyan Yuan, Di Wang, Meng Li, Bo Xie, Xuqiang Zou, Mingjie Lu, Ye Qiu, Jinlin Song   +8 more
wiley   +1 more source

Physical activity and meal timing alignment with chronotype and their associations with glucose metabolism: The Maastricht Study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Little is known about how the alignment between daily behaviours, such as physical activity and eating, and chronotype relates to glucose metabolism. We investigated whether alignment of physical activity and meal timing with chronotype was associated with glycaemic parameters and with prediabetes or type 2 diabetes (T2DM).
Marvin Y. Chong, Joseph Henson, Martijn J. L. Bours, Hans Bosma, Bastiaan E. de Galan, Carla J. H. van der Kallen, Ree M. Meertens, Hans H. C. M. Savelberg, Miranda T. Schram, Matty P. Weijenberg, Thomas Yates, Annemarie Koster, Simone J. P. M. Eussen   +12 more
wiley   +1 more source

Waning light, waxing pain: The lunar cycle's association with migraine headache occurrence

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary While migraine headaches can be hard to predict, some patients believe headaches are connected to the moon‘s phases. Our research showed that migraine attacks were 34% more likely to occur during the new moon than during the full moon.
Alexander Yoo, Brendan Keenan, Angeliki Vgontzas, Murray A. Mittleman, Suzanne M. Bertisch, Ron Anafi   +5 more
wiley   +1 more source

Toward a global repository of insect traits (GRIT)

Insect Conservation and Diversity, EarlyView.
Biodiversity loss is accelerating, yet insect conservation is hindered by the absence of a centralised, comprehensive trait database. We propose the GRIT, a FAIR, open‐access platform uniting datasets and collaborators worldwide. GRIT will harness advanced computational tools for trait acquisition and imputation, enabling large‐scale ecological ...
Pedro Cardoso, Nathan Jay Baker, Mário Boieiro, Dries Bonte, Paulo A. V. Borges, Michael F. Braby, Vasco Branco, Dragan Chobanov, Luis Correia, Daniel T. Dalton, Mariana Damas‐Mora, Raphael K. Didham, Lynne Forster, Richard Glatz, Jacob A. Gorneau, Axel Hochkirch, Ameli Kirse, Elinor M. Lichtenberg, Nuria Macías‐Hernández, Marija Miličić, Melinda Moir, Pablo Moreno‐García, Ruth Neessen, Jorge Ari Noriega, Clint A. Penick, Kayla I. Perry, James Pryke, Carla Rego, Karl A. Roeder, Stéphanie Saussure, Vaughn Shirey, Pasi Sihvonen, Ilja Svetnik, Sergei Tarasov, Pedro Trindade, Ellen A. R. Welti, Mark Wong, Christoph Scherber   +37 more
wiley   +1 more source

A Lavandula angustifolia flower extract and dipeptide‐4 blend modulates oxidative, glycative, autophagic and circadian pathways in human skin models

International Journal of Cosmetic Science, EarlyView.
The blend enhanced antioxidation, anti‐glycation, autophagy and circadian regulation in cell and skin models. Key markers included mitochondrial ROS, γ‐H2AX, AGEs, ATP, melatonin, LC3 and SOD. Significant improvements were visualized via fluorescence and quantified with statistical markers.
Lina Wang, Yuxuan Wu, Huiping Hu, Yanan Li, Peiwen Sun   +4 more
wiley   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, EarlyView.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source

Genetic Parameter Estimation for Plasma Biomarkers Associated With Energy Reserves During Critical Physiological Stages in Sheep

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The ability of ruminants to mobilise and restore body reserves (BR) over time, referred to as BR dynamics, is currently considered an interesting biological component to be included in breeding programs targeting enhanced BR resilience. However, genetic studies of proxies for BR levels and BRD remain scarce, particularly in small ruminants ...
Agnes Nyamiel, Andres Legarra, Didier Marcon, Christian Durand, Sébastien Douls, Gaetan Bonnafe, Anne Tesnière, Eliel González‐García, Dominique Hazard   +8 more
wiley   +1 more source