Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawal [PDF]
Every physiological function in the human body exhibits some form of circadian rhythmicity. Under pathological conditions, however, circadian rhythmicity may be dusrupted.
Ding, Jian M.+9 more
core +3 more sources
Observation and detection of neurotransmitter dynamics in aqueous system has been hurdle for analytical fields due to its weak and reversible nature. A terahertz‐nanodisc metasurface which implements comprehensive detection over conformational change and selective sensing is introduced. Utilizing the THz regime photonics and biomimetic environment with
Taeyeon Kim+6 more
wiley +1 more source
Voluntary exercise can strengthen the circadian system in aged mice [PDF]
Consistent daily rhythms are important to healthy aging according to studies linking disrupted circadian rhythms with negative health impacts. We studied the effects of age and exercise on baseline circadian rhythms and on the circadian system's ability ...
A Davidson+74 more
core +2 more sources
New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini+7 more
wiley +1 more source
The circadian rhythm regulates the daily cycles of various physiological activities. Accumulating evidences revealed that circadian rhythm plays an important role in regulating metabolic homeostasis, and disruptions of circadian rhythms resulting in ...
Huijun Cheng+5 more
doaj
Circadian Organization in Hemimetabolous Insects [PDF]
The circadian system of hemimetabolous insects is reviewed in respect to the locus of the circadian clock and multioscillatory organization. Because of relatively easy access to the nervous system, the neuronal organization of the clock system in ...
Abe Y.+17 more
core +1 more source
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao+14 more
wiley +1 more source
Effect of exercise based interventions on sleep and circadian rhythm in cancer survivors—a systematic review and meta-analysis [PDF]
Background Disrupted circadian rhythm commonly reported in cancer survivors is closely associated with cancer related fatigue, sleep disturbances and compromised quality of life.
Rachita Gururaj+4 more
doaj +2 more sources
Krüppel-like factor 7 deficiency causes autistic-like behavior in mice via regulating Clock gene
Background Krüppel-like factor 7 (klf7), a transcription factor in the nervous system to regulate cell proliferation and differentiation, has been recently identified as a causal gene for autism spectrum disorder (ASD), but the mechanism behind remains ...
Hui Tian+7 more
doaj +1 more source
Effect of deuterium on the circadian period and metabolism in wild-type and tau mutant Syrian hamsters [PDF]
Homozygous tau mutant Syrian hamsters (tau-/-) have a free-running circadian period (τ) around 20 h and a proportionally higher metabolic rate compared with wild-type hamsters (tau+/+) with a period of circa 24 h.
Daan, Serge,+2 more
core +1 more source