Results 81 to 90 of about 136,810 (312)

The TIME FOR COFFEE gene maintains the amplitude and timing of Arabidopsis circadian clocks [PDF]

open access: yes, 2003
Plants synchronize developmental and metabolic processes with the earth's 24-h rotation through the integration of circadian rhythms and responses to light.
Amasino, R.   +40 more
core   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

Evaluation of QT Liability for PF‐05251749 in the Presence of Potential Circadian Rhythm Modification

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2020
PF‐05251749 is a dual inhibitor of casein kinase 1 δ/ε, key regulators of circadian rhythm. As a result of its mechanism of action, PF‐05251749 may also change the heart rate corrected QT (QTc) circadian rhythm, which may confound detection of drug ...
Yeamin Huh   +4 more
doaj   +1 more source

Modeling the effect of oscillation in receptor expression on synchrony in the mammalian circadian model [PDF]

open access: yes, 2011
The suprachiasmatic nucleus (SCN) is located in the hypothalamus and contains the circadian mammalian pacemaker that is responsible for endogeneous biological timekeeping.
Saccoman, Claudia
core  

The effect of a non-circadian photoperiod on the growth, physiology, and production of a romaine lettuce cultivar [PDF]

open access: yes, 2022
The circadian rhythm serves to match plant physiology and behavior with the environmental cycles caused by the rotation of the planet. The circadian rhythm contributes towards the structure and function of plants and their overall performance which ...
Hughes, Joshua
core  

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

Effect of exercise based interventions on sleep and circadian rhythm in cancer survivors—a systematic review and meta-analysis [PDF]

open access: yesPeerJ
Background Disrupted circadian rhythm commonly reported in cancer survivors is closely associated with cancer related fatigue, sleep disturbances and compromised quality of life.
Rachita Gururaj   +4 more
doaj   +2 more sources

Robustness from flexibility in the fungal circadian clock [PDF]

open access: yes, 2010
Background Robustness is a central property of living systems, enabling function to be maintained against environmental perturbations. A key challenge is to identify the structures in biological circuits that confer system-level properties such as ...
Andrew J Millar   +13 more
core   +1 more source

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

open access: yesAdvanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari   +3 more
wiley   +1 more source

Research progress on correlation between circadian rhythm disturbance and work-related musculoskeletal disorders

open access: yes环境与职业医学
Circadian rhythm refers to the 24-hour periodic changes in behavior, physiology, and molecular processes in the human body. Disruptions to the circadian rhythm not only affect mental health but are also associated with various metabolic disorders ...
Lichong LAI   +5 more
doaj   +1 more source

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