Circadian rhythm - Open Access .click

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The contributions of interlocking loops and extensive nonlinearity to the properties of circadian clock models [PDF]

, 2010
Sensitivity and robustness are essential properties of circadian clock systems, enabling them to respond to the environment but resist noisy variations. These properties should be recapitulated in computational models of the circadian clock.
Andrew J Millar +15 more
core +1 more source

Lutzomyia longipalpis circadian rhythm pathway annotation.

, 2023
Lutzomyia longipalpis circadian rhythm pathway annotation.
Antonio Carlos A. Meireles-Filho (15213879) +82 more
core +1 more source

Circadian‐Inspired Hydrogel Moisture Electricity Generation

Advanced Science, EarlyView.
A circadian‐inspired hydrogel moisture‐electric generator enables sustainable electricity generation by autonomously current direction switching between daytime and nighttime. This reversible output is accompanied by inversion of the internal water gradient, which effectively reduce hydrogel fatigue and offers a new strategy for harvesting diurnal ...
Ziqi Li +7 more
wiley +1 more source

Krüppel-like factor 7 deficiency causes autistic-like behavior in mice via regulating Clock gene

Cell & Bioscience, 2022
Background Krüppel-like factor 7 (klf7), a transcription factor in the nervous system to regulate cell proliferation and differentiation, has been recently identified as a causal gene for autism spectrum disorder (ASD), but the mechanism behind remains ...
Hui Tian +7 more
doaj +1 more source

The Neurobiology of Circadian Rhythms

Psychiatric Clinics of North America, 2015
There is a growing recognition that the coordinated timing of behavioral, physiologic, and metabolic circadian rhythms is a requirement for a healthy body and mind. In mammals, the primary circadian oscillator is the hypothalamic suprachiasmatic nucleus (SCN), which is responsible for circadian coordination throughout the organism. Temporal homeostasis
Sollars, Patricia J., Pickard, Gary E.
openaire +3 more sources

Developmental Environmental Chronotoxicity by Polystyrene Nanoplastics Exacerbates High‐Fat Diet‐Induced Pediatric MAFLD Through Circadian Disruption and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Polystyrene nanoplastics exacerbate high‐fat diet‐induced metabolic dysfunction in an age‐dependent manner. Juvenile mice exhibit greater susceptibility, characterized by circadian disruption, impaired mitochondrial function, reduced energy metabolism, and enhanced hepatic lipid accumulation.
Peihao Xu +10 more
wiley +1 more source

Research progress on correlation between circadian rhythm disturbance and work-related musculoskeletal disorders

环境与职业医学
Circadian rhythm refers to the 24-hour periodic changes in behavior, physiology, and molecular processes in the human body. Disruptions to the circadian rhythm not only affect mental health but are also associated with various metabolic disorders ...
Lichong LAI +5 more
doaj +1 more source

Effect of exercise based interventions on sleep and circadian rhythm in cancer survivors—a systematic review and meta-analysis [PDF]

PeerJ
Background Disrupted circadian rhythm commonly reported in cancer survivors is closely associated with cancer related fatigue, sleep disturbances and compromised quality of life.
Rachita Gururaj +4 more
doaj +2 more sources

Evaluation of QT Liability for PF‐05251749 in the Presence of Potential Circadian Rhythm Modification

CPT: Pharmacometrics & Systems Pharmacology, 2020
PF‐05251749 is a dual inhibitor of casein kinase 1 δ/ε, key regulators of circadian rhythm. As a result of its mechanism of action, PF‐05251749 may also change the heart rate corrected QT (QTc) circadian rhythm, which may confound detection of drug ...
Yeamin Huh +4 more
doaj +1 more source

Phlebotomus papatasi circadian rhythm pathway annotation.

, 2023
Phlebotomus papatasi circadian rhythm pathway annotation.
Antonio Carlos A. Meireles-Filho (15213879) +82 more
core +1 more source

medicine
melatonin
circadian clock