Results 81 to 90 of about 492,257 (392)

The impact of short-term changes in sleeping and eating patterns on glucometabolic health and gut microbiota in healthy young adults: a proof-of-concept controlled feeding study

Food Science and Human Wellness
Epidemiological studies showed that night workers are at higher risk of developing chronic metabolic diseases. However, no study has investigated the changes in circadian rhythms caused by a combined effect of sleep and diet in a real-life setting on ...
Jiehua Chen, Ruijie Zhang, Chao Zhou, Louise Weiwei Lu, Dana Feng, Haiqiao Zou, Ran Gao, Xinying Zhang, Peiyi Chen, Jiayue Zhu, Haoxie Xu, Nina Zeng, Cijuan Zhang, Bin Liu, Mingfu Wang, Qian Ge, Caiqun Ouyang, Feng Chen   +17 more
doaj   +1 more source

Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawal [PDF]

, 2006
Every physiological function in the human body exhibits some form of circadian rhythmicity. Under pathological conditions, however, circadian rhythmicity may be dusrupted.
Ding, Jian M., Jiang, Zhou, Liu, Yanyou, Wan, Chaomin, Wang, Xiaojia, Wang, Yueqi, Wang, Yuhui, Wang, Zhengrong, Xin, Haoyang, Zheng, Hang   +9 more
core   +3 more sources

The mammalian circadian system: a hierarchical multi-oscillator structure for generating circadian rhythm

Journal of Physiological Sciences, 2018
The circadian nature of physiology and behavior is regulated by a circadian clock that generates intrinsic rhythms with a periodicity of approximately 24 h. The mammalian circadian system is composed of a hierarchical multi-oscillator structure, with the
S. Honma
semanticscholar   +1 more source

Closed-loop cascade nanozyme strategy for mutually reinforced catalytic and mild-temperature photothermal therapeutic effects

Journal of Nanobiotechnology
Nanocatalysis coupled with photothermal therapy is a potent anti-cancer approach, yet its clinical utility is limited by low concentration of tumor substrate, redox interference, and risks of overheating normal tissues.
Fan Yang, Chunyu Yan, Nannan Li, Xinxiu Jiang, Baojie Du, Peirong Bai, Liping Li, Ruiping Zhang   +7 more
doaj   +1 more source

Analysis of Saccharomyces cerevisiae Circadian Rhythms in Continuous Culture [PDF]

, 2012
The circadian rhythm is a roughly 24-hour cycle in the physiological processes of organisms. There have been many studies on the circadian rhythms in other model organisms, but not in Saccharomyces cerevisiae. To study the rhythm in S.
Kohner, Melissa, Lyons, Carlton, Zager, Lauren   +2 more
core   +2 more sources

Aging and circadian rhythms [PDF]

Current Opinion in Insect Science, 2015
Circadian clocks are cell-autonomous molecular feedback loops that generate daily rhythms in gene expression, cellular functions, physiological processes and behavior. The mechanisms of circadian clocks are well understood in young fruit flies Drosophila melanogaster, but less is known about how circadian system changes during organismal aging. Similar
Dani M Long, Jadwiga M. Giebultowicz
openaire   +3 more sources

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Circadian rhythms of proliferation events in two mouse carcinomas [PDF]

, 2015
We studied the index of DNA synthesis (DNAs) of two cellular carcinomas: the hepatocellular ES12a and the mammary TN60 of mice, throughout one circadian cycle.
Andrini, Laura Beatríz, Errecalde, Ana Lia, Garcia, Marcela, Inda, Ana, Martinez, Marina, Miriuka, Santiago Gabriel, Palma, Maria Belen   +6 more
core   +1 more source

Circadian Rhythm Disturbances in Mood Disorders: Insights into the Role of the Suprachiasmatic Nucleus

Journal of Neural Transplantation and Plasticity, 2017
Circadian rhythm disturbances are a common symptom among individuals with mood disorders. The suprachiasmatic nucleus (SCN), in the ventral part of the anterior hypothalamus, orchestrates physiological and behavioral circadian rhythms.
C. Vadnie, C. Mcclung
semanticscholar   +1 more source

Circadian Rhythms Disrupted by Light at Night and Mistimed Food Intake Alter Hormonal Rhythms and Metabolism

International Journal of Molecular Sciences, 2023
Availability of artificial light and light-emitting devices have altered human temporal life, allowing 24-hour healthcare, commerce and production, and expanding social life around the clock.
M. Zeman, H. Korf, O. H. M. É. N. Á. ndez, Jennifer A. Liu, Randy J. Nelson   +4 more
semanticscholar   +1 more source