Results 241 to 250 of about 86,709 (313)

Sleep disruption and its psychological treatment in young people at risk of psychosis: A peer methods qualitative evaluation

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Objectives A recent randomized controlled feasibility trial showed that sleep problems in young people at risk of psychosis can be successfully treated with psychological therapy and that this may bring additional benefits such as reducing depression, anxiety and paranoia.
Felicity Waite   +8 more
wiley   +1 more source

From barriers to benefits: A personalized sleep intervention enhances sleep duration and emotional health in chronic short sleepers

open access: yesBritish Journal of Psychology, EarlyView.
Abstract This pilot study evaluated a personalized sleep intervention incorporating motivational interviewing techniques to address sleep barriers, along with tailored sleep hygiene and extension for chronic short sleepers. Eleven university students completed a 14‐day sequential intervention (baseline, sleep hygiene and a combined phase adding 90‐min ...
Wei Wang   +11 more
wiley   +1 more source

Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space

open access: yesBrain Pathology, EarlyView.
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle   +7 more
wiley   +1 more source

Circadian rhythms as a modulator of gut microbiota-tumor microenvironment crosstalk. [PDF]

open access: yesCell Mol Life Sci
Xu Q   +10 more
europepmc   +1 more source

Polarized effects of adenosine on blood–brain barrier integrity: Tightening from the luminal and opening from the abluminal side

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Adenosine as a signalling molecule modifies blood–brain barrier (BBB) tightness in pathological conditions. Our aim was to investigate the direct and polarized effects of adenosine on the BBB using co‐culture and in vivo models. Experimental Approach The expression of adenosine receptors was measured by qRT‐PCR.
András Harazin   +10 more
wiley   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci   +15 more
wiley   +1 more source

Bidirectional interactions between circadian rhythms and the gut microbiome. [PDF]

open access: yesAppl Microbiol Biotechnol
Bautista J   +5 more
europepmc   +1 more source

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