Results 241 to 250 of about 206,395 (302)

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Dietary melatonin and its benefits on cardiovascular disease

British Journal of Pharmacology, EarlyView.
Cardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low‐ and middle‐income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable antioxidant, anti‐inflammatory and immunomodulatory properties that may confer cardiovascular benefits.
Karabo Tisane, Carmelita Abrahams, Sandrine Lecour   +2 more
wiley   +1 more source

Dear Influencers: Don't Disturb Amphibians and Reptiles for More Followers

Animal Conservation, EarlyView.
José Guerrero‐Casado, Ricardo Reques
wiley   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Timekeepers of the gut: host circadian rhythms and microbial modulators. [PDF]

Life Metab
Ma X, Yu Q, Kuang Z.
europepmc   +1 more source

Roux-en-Y gastric bypass alters microbial circadian rhythms with links to metabolic improvement. [PDF]

Am J Physiol Gastrointest Liver Physiol
Moutsoglou D, Jarrah M, Jaques J, Aguilar L, Shahi SK, Mangalam AK, Mokadem M.   +6 more
europepmc   +1 more source

The Transcription Factors Six3 and Six6 in Neuromedin-S Neurons Differentially Affect Circadian Rhythms. [PDF]

J Neurosci Res
Van Loh BM, Dunn GA, Chun LE, Patel MM, Naing NCP, Nguyen D, Yaw AM, Gorman MR, Cassin J, Mellon PL, Hoffmann HM, Tonsfeldt KJ.   +11 more
europepmc   +1 more source

Circadian Rhythms and Glucocorticoid Dynamics in the Kidney Matrix.

Nephron
Gyasi C, Lennon R, Preston R.
europepmc   +1 more source

Pharmacological modulation of circadian rhythms in brain microvasculature. [PDF]

J Cereb Blood Flow Metab
Yang Z, Kim M, Montgomery M, Lewandowski A, Ho A, Buchwald ZS, Zhang SL.   +6 more
europepmc   +1 more source

Circadian rhythms and microbiota: molecular crosstalk and its implications for health and disease. [PDF]

Biol Direct
Wu G, Zhang J, Yan S, Liu N, Chen W, Wu F, Wang Z, Zhang J, Yang Y, Deng Y, Qiu X, Liu J, Shi L, Cui X, Wan R, Li X, Han Y, Yang G.   +17 more
europepmc   +1 more source