Results 231 to 240 of about 213,878 (305)

Dietary melatonin and its benefits on cardiovascular disease

British Journal of Pharmacology, EarlyView.
Cardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low‐ and middle‐income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable antioxidant, anti‐inflammatory and immunomodulatory properties that may confer cardiovascular benefits.
Karabo Tisane, Carmelita Abrahams, Sandrine Lecour   +2 more
wiley   +1 more source

Chrono-Nanomedicine at the Barrier: Circadian Rhythms Influence the Delivery of Donepezil Across the BCSFB. [PDF]

Int J Mol Sci
Cardoso MR, Duarte AC, Mineiro R, Ferreira M, Sousa Â, Gallardo E, Ishikawa H, Schwerk C, Schroten H, Santos C, Costa D, Quintela T.   +11 more
europepmc   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Circadian rhythms and lung cancer biology and immunotherapy: Emerging opportunities and challenges. [PDF]

Chin Med J Pulm Crit Care Med
Tian F, Wang S, Huang Z, Ruan Z, Dai J, Yan H, Huang J, Yang D, Li X, Zeng L, Xu Q, Zhang Y.   +11 more
europepmc   +1 more source

Macrophage Lipid Homeostasis Drives IVDD via a Senescence‐Dependent Impairment of Efferocytosis

Cell Proliferation, EarlyView.
Intervertebral disc degeneration (IVDD) has been a leading cause of low back pain and lacks disease‐modifying therapies. Although dysregulated disc lipid metabolism is implicated, its impact on the immune microenvironment, particularly macrophages, remains unknown.
Jinyu Wang, Shiyong Ling, Qi Wang, Xuege Qiao, Jianpeng Xing, Siyang Ji, Linhui Han, Chen Yan, Zhishen Niu, Lei Yuan, Baolian Zhao, Kaiqiang Sun, Jiangang Shi   +12 more
wiley   +1 more source

Circadian Rhythms Time Seizure Severity in <i>Drosophila</i>. [PDF]

J Biol Rhythms
Huertas-Radi M, Bradlaugh AA, Baines RA.
europepmc   +1 more source

Sleep health of adults with cerebral palsy: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
Although many people with cerebral palsy (CP) are adults, most sleep research in CP focuses on children. As poor sleep can affect pain, mood, energy, daily functioning, and quality of life we reviewed what is currently known about the sleep health of adults with CP. We searched three major research databases (MEDLINE, Embase, and CINAHL) up to February
Deepika Nagabhushan, Caleb Kim, Daniel G. Whitney, Rita Ayyangar, Angeline Bowman, Sonia Sharma, Maxwell S. Barnish, Daniel Whibley   +7 more
wiley   +1 more source

Gut microbiota-mediated modulation of circadian rhythms: Physiological and molecular impacts of dietary composition and feeding time. [PDF]

J Food Drug Anal
Koh YC, Chang CC, Pan MH.
europepmc   +1 more source