Results 21 to 30 of about 247 (93)

eIF4A3‐induced circWAC promotes breast cancer progression through mediating miR‐599/E2F3 axis

The Kaohsiung Journal of Medical Sciences, Volume 38, Issue 4, Page 321-335, April 2022., 2022
Abstract Circular RNAs (circRNAs) are implicated in the regulation of tumor progression via the “competitive endogenous RNAs (ceRNAs)” mechanism. We intended to explore the molecular mechanism of circRNA WW domain containing adaptor with coiled‐coil (circWAC) in breast cancer (BC) progression.
Wen‐Hui Huang, Qing Yang, Chuan Zhang
wiley   +1 more source

hsa_circ_0000518 Facilitates Non‐Small‐Cell Lung Cancer Progression via Moderating miR‐330‐3p and Positively Regulating SLC1A5

Journal of Immunology Research, Volume 2022, Issue 1, 2022., 2022
Background/Aim. Non‐small‐cell lung cancer (NSCLC) is the principal agent of cancer deaths globally. The goal of this study was to determine how circular RNA_0000518 (circ_0000518) regulates tumor progression. Materials/Methods. circ_0000518 was selected as a study target involved in NSCLC from GEO (Gene Expression Omnibus) database. circ_0000518 level
Huilai Lv, Zhihua Shi, Aixia Sui, Yan Zhang, Liangbiao Peng, Mingbo Wang, Fan Zhang, Fu Wang   +7 more
wiley   +1 more source

Novel insights into exosomal circular RNAs: Redefining intercellular communication in cancer biology

Clinical and Translational Medicine, Volume 11, Issue 12, December 2021., 2021
Circular RNAs (circRNAs) can exert their functions via exosome delivery to recipient cells. Exosomal circRNAs are involved in tumour‐to‐tumour crosstalk, tumour‐to‐stroma crosstalk and stroma‐to‐tumour crosstalk in the tumour microenvironment. Exosomal circRNAs are promising diagnostic, prognostic and predictive biomarkers for cancer, and exosomes ...
Huimin Lin, Jie Yu, Xiang Gu, Shengfang Ge, Xianqun Fan   +4 more
wiley   +1 more source

circAMOTL1L Suppresses Renal Cell Carcinoma Growth by Modulating the miR‐92a‐2‐5p/KLLN Pathway

Oxidative Medicine and Cellular Longevity, Volume 2021, Issue 1, 2021., 2021
Accumulating evidence indicates that the dysregulation of circular RNAs (circRNAs) contributes to tumor progression; however, the regulatory functions of circRNAs in renal cell carcinoma (RCC) remain largely unknown. In this study, the function and underlying mechanism of circAMOTL1L in RCC progression were explored.
Ling Gao, Xian Shao, Qingqing Yue, Weifei Wu, Xuejuan Yang, Xiaolei He, Limin Li, Fujun Hou, Ruonan Zhang, Fabio Ciccarone   +9 more
wiley   +1 more source

Circ-PRMT5 promotes gastric cancer progression by sponging miR-145 and miR-1304 to upregulate MYC

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Background Gastric cancer (GC) is a global leading source of cancer-associated deaths. Circular RNAs (circRNAs) are a new type of non-coding RNA and promising biomarkers for diagnosis of multiple diseases such as cancer.Methods Circ-PRMT5 expression was ...
Wenbo Du, Ding Li, Xiaomin Guo, Ping Li, Xin Li, Shuping Tong, Junhui Tong, Lihua Kuang, Daoming Liang   +8 more
doaj   +1 more source

Επιγενετικές αλλαγές στο ουροθηλιακό καρκίνωμα της ουροδόχου κύστης [PDF]

, 2021
Το ουροθηλιακό καρκίνωμα αποτελεί την πιο κοινή νεοπλασία της ουροδόχου κύστης. Λόγω της υψηλής συχνότητας εμφάνισής του, του επιπολασμού, της υποτροπής και της θνησιμότητας του, παραμένει ένα άλυτο κλινικό και κοινωνικό πρόβλημα. Οι επιγενετικές αλλαγές,
Kokla Georgia, Κόκλα Γεωργία
core  

Epigenetics of Bladder Cancer: Where Biomarkers and Therapeutic Targets Meet [PDF]

, 2019
El c??ncer de vejiga (BC) es la neoplasia m??s com??n del tracto urotelial. Debido a su alta incidencia, prevalencia, recurrencia y mortalidad, sigue representando un problema cl??nico y social no resuelto.
Bernardini, Alejandra, Due??as, Marta, G Martinez, Victor, Lodewijk, Iris, Mart??nez-Fern??ndez, M??nica, Munera-Maravilla, Ester, Paramio, Jes??s Maria, Rubio, Carolina, Segovia, Cristina, Suarez-Cabrera, Cristian   +9 more
core   +1 more source

Potential Role of Exosomes in Cancer Metastasis

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
High cancer mortality is attributed to metastasis to a large extent. However, cancer metastasis remains devoid of dynamic monitoring and early prevention in terms of current advances in diagnostic means and therapeutic modalities. Meanwhile, studies have shown that reciprocal crosstalk among cells via exosomes plays a critical role in maintaining ...
Wenjuan Tian, Shanshan Liu, Burong Li, Shi-Cong Tao   +3 more
wiley   +1 more source

New Perspectives on the Role of Liquid Biopsy in Bladder Cancer: Applicability to Precision Medicine. [PDF]

Bladder cancer (BC) is one of the most common tumors in the world. Cystoscopy and tissue biopsy are the standard methods in screening and early diagnosis of suspicious bladder lesions.
Alberca-Del Arco, Fernardo, Herrera-Imbroda, Bernardo, Matas-Rico, Elisa, Prieto-Cuadra, Daniel, Santos-Perez de la Blanca, Rocio, Sáez-Barranquero, Felipe   +5 more
core   +1 more source

RNAs in tumour‐derived extracellular vesicles and their significance in the tumour microenvironment

International Journal of Cancer, Volume 155, Issue 7, Page 1147-1161, 1 October 2024.
Abstract Small extracellular vesicles (sEVs) secreted by various types of cells serve as crucial mediators of intercellular communication within the complex tumour microenvironment (TME). Tumour‐derived small extracellular vesicles (TDEs) are massively produced and released by tumour cells, recapitulating the specificity of their cell of origin.
Maria Bugajova, Martina Raudenska, Michal Masarik, David Kalfert, Jan Betka, Jan Balvan   +5 more
wiley   +1 more source