Results 31 to 40 of about 247 (93)
Intricate relationship between cancer stemness, metastasis, and drug resistance
MedComm, Volume 5, Issue 10, October 2024.Complexity of cancer stem cell biology and the intricate relationship between cancer stem cells, metastasis, and drug resistance Abstract Cancer stem cells (CSCs) are widely acknowledged as the drivers of tumor initiation, epithelial‐mesenchymal transition (EMT) progression, and metastasis. Originating from both hematologic and solid malignancies, CSCs
Tikam Chand Dakal +9 more
wiley +1 more source
Circular RNAs in human diseases
MedComm, Volume 5, Issue 9, September 2024.Circular RNAs (circRNAs) play significant roles in various human diseases, including respiratory, endocrine, metabolic, musculoskeletal, cardiovascular, renal diseases, and cancer. This review highlights their biogenesis, pathogenic potential, and potential applications as diagnostic biomarkers and therapeutic targets. Abstract Circular RNAs (circRNAs)
Yuanyong Wang +10 more
wiley +1 more source
Circular RNAs in colorectal cancer: Emerging insights and future perspectives. [PDF]
Circular RNAs (circRNAs) are a distinct class of long non-coding RNAs characterized by their covalently closed-loop structure, which confers high stability.
Behera, Roopal +6 more
core +2 more sources
, 2018 Supplementary Figure S1. CircPRMT5 is upregulated in UCB cells. Supplementary Figure S2. CircPRMT5 promotes migration and invasion of UCB cells. Supplementary Figure S3. CircPRMT5 contains multiple target sites of miRNAs.
Dan Xie (41844) +14 more
core +2 more sources
circPRMT5通过靶向miR-98-5p对膀胱癌细胞增殖、迁移侵袭的机制研究
Zhongguo shiyan zhenduanxue目的 探究circPRMT5通过靶向miR-98-5p对膀胱癌细胞增殖、迁移侵袭的机制研究。方法 qRT-PCR检测永生化正常尿路上皮细胞SV-HUC-1和膀胱癌细胞(T24、J82、HT-1376)中circPRMT5、miR-98-5p和X染色体连锁的凋亡抑制蛋白(XIAP)mRNA相对表达水平。核糖核酸酶(RNase)R和放线菌素D的消化实验鉴定circPRMT5的环状结构。将T24细胞分为si-NC组、si-circPRMT5组、miR-NC组、miR-98-5p组、si-circPRMT5 ...
谢奕彪, 姜良真, 崔小健
doaj
Sequences information for gene knockdown.
Research has demonstrated that circular RNAs (circRNAs) exert critical functions in the occurrence and progression of numerous malignant tumors. CircPRMT5 was recently reported to be involved in the pathogenesis of cancers. However, the potential role of
Hongyan Jiang (3058782) +6 more
core +2 more sources
Research has demonstrated that circular RNAs (circRNAs) exert critical functions in the occurrence and progression of numerous malignant tumors. CircPRMT5 was recently reported to be involved in the pathogenesis of cancers. However, the potential role of
Hongyan Jiang (3058782) +6 more
core +2 more sources
CircPRMT5 promotes the proliferation, invasion and migration of osteosarcoma cells.
A. The efficacy of circPRMT5 overexpression or sh-circPRMT5 plasmid in MNNG/HOS and MG-63 cells detected by qRT-PCR. B. MTT assay in MNNG/HOS and MG-63 cells after circPRMT5 overexpression or knockdown. C.
Hongyan Jiang (3058782) +6 more
core +2 more sources
CircPRMT5 is highly expressed in osteosarcoma cells and mainly located in the cytoplasm.
A. Sanger sequencing results of circPRMT5. B. DNA electrophoresis of the PCR products from divergent or convergent primers. C. qRT-PCR results of circPRMT5 expression in hFOB1.19 cells and osteosarcoma cell lines. D-E.
Hongyan Jiang (3058782) +6 more
core +2 more sources
Research has demonstrated that circular RNAs (circRNAs) exert critical functions in the occurrence and progression of numerous malignant tumors. CircPRMT5 was recently reported to be involved in the pathogenesis of cancers. However, the potential role of
Hongyan Jiang (3058782) +6 more
core +2 more sources