Results 21 to 30 of about 72,141 (255)

Speech acoustic indices for differential diagnosis between Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy

open access: yesnpj Parkinson's Disease, 2022
While speech disorder represents an early and prominent clinical feature of atypical parkinsonian syndromes such as multiple system atrophy (MSA) and progressive supranuclear palsy (PSP), little is known about the sensitivity of speech assessment as a ...
Khalid Daoudi   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Ultra-Low-Power 0.35-V 0.63-nW/kHz Multi-Stacked Clock Oscillator With Adjustable Frequency and Duty-Cycling

open access: yesIEEE Access
This paper presents the analysis, design, and characterization of an on-chip ultra-low-power clock oscillator for sensor nodes, implemented in 130nm BiCMOS technology.
Seyyedmohsen Seyyedrezaei   +2 more
doaj   +1 more source

Microwave functionality of spintronic devices implemented in a hybrid complementary metal oxide semiconductor and magnetic tunnel junction technology

open access: yesElectronics Letters, 2021
This letter presents magnetic tunnel junction based spintronic devices completely implemented in a hybrid semiconductor process that comprises a complementary metal oxide semiconductor and a magnetic tunnel junction technology.
Rui Ma   +14 more
doaj   +1 more source

Tracing Power With Circuit Theory

open access: yesIEEE Transactions on Smart Grid, 2020
Power tracing is the task of disaggregating the power injection of a generator (or a load) into a sum of constituent components that can unambiguously be attributed to loads (generators) and losses. Applications of power tracing range the broad spectrum of: transmission services pricing, loss allocation in distribution networks, fixed-cost allocation ...
Yu Christine Chen, Sairaj V. Dhople
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact of Frequency Heterogeneity on Mutually Synchronized Spatially Distributed 24 GHz PLLs

open access: yesIEEE Open Journal of Circuits and Systems
This research analyzes the mutual self-organized synchronization of phase-locked loops (PLLs) in the presence of variations in the free-running frequency of a PLL.
Christian Hoyer   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Modulation Bandwidth Investigation of Voltage-Controlled Oscillators Under Periodic Linear Frequency Modulation

open access: yesIEEE Open Journal of Circuits and Systems
The modulation bandwidth of a voltage-controlled oscillator (VCO) is a key design metric that defines its ability to respond to fast tuning voltages and change its frequency accordingly. While prior works have addressed practical methods for measuring it,
Rabia Fatima Riaz   +2 more
doaj   +1 more source

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