Results 31 to 40 of about 72,141 (255)
Scientific Reports, 2017 For generations, the evaluation of speech abnormalities in neurodegenerative disorders such as Parkinson’s disease (PD) has been limited to perceptual tests or user-controlled laboratory analysis based upon rather small samples of human vocalizations ...
Jan Hlavnička +5 more
doaj +1 more source
Hypernasality associated with basal ganglia dysfunction: evidence from Parkinson’s disease and Huntington’s disease [PDF]
PeerJ, 2016 Background Although increased nasality can originate from basal ganglia dysfunction, data regarding hypernasality in Parkinson’s disease (PD) and Huntington’s disease (HD) are very sparse.
Michal Novotný +5 more
doaj +2 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
IEEE AccessHigh performance anti-aliasing filters (AAF) are critical components of advanced frequency interleaved (FI) analog-to-digital converter (ADC) structures, which are capable of overcoming the sample-clock jitter limit for ultra-high speed power efficient ...
Anton Lorenz +2 more
doaj +1 more source
New Discrete Fibonacci Charge Pump Design, Evaluation and Measurement
Measurement Science Review, 2017 This paper focuses on the practical aspects of the realisation of Dickson and Fibonacci charge pumps. Standard Dickson charge pump circuit solution and new Fibonacci charge pump implementation are compared.
Matoušek David +2 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Cross-Coupled Charge Pump Synthesis Based on Full Transistor-Level
Advances in Electrical and Electronic Engineering, 2019 This paper presents utility for the design of the cross-coupled charge pump, which is used for supplying peripherals with low current consumption on the chip, as the EEPROM or FLASH memories.
Jan Marek, Jiri Hospodka, Ondrej Subrt
doaj +1 more source
ICT Express, 2020 A new method is proposed to improve the accuracy of locating buried objects in heterogeneous environments using shifted time pulses with radio impulse ultra wide band (IR-UWB), time-hopping pulse position modulation (TH-BPSK UWB), binary phase shift ...
Nguyen Thi Huyen +2 more
doaj +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source