Results 51 to 60 of about 825,271 (288)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Cross-Coupled Charge Pump Synthesis Based on Full Transistor-Level

Advances in Electrical and Electronic Engineering, 2019
This paper presents utility for the design of the cross-coupled charge pump, which is used for supplying peripherals with low current consumption on the chip, as the EEPROM or FLASH memories.
Jan Marek, Jiri Hospodka, Ondrej Subrt
doaj   +1 more source

Buried objects detection in heterogeneous environment using UWB systems combined with curve fitting method

ICT Express, 2020
A new method is proposed to improve the accuracy of locating buried objects in heterogeneous environments using shifted time pulses with radio impulse ultra wide band (IR-UWB), time-hopping pulse position modulation (TH-BPSK UWB), binary phase shift ...
Nguyen Thi Huyen, Duong Duc Ha, Pham Thanh Hiep   +2 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Circuit Theory in Projective Space and Homogeneous Circuit Models [PDF]

IEEE Transactions on Circuits and Systems I: Regular Papers, 2019
This paper presents a general framework for linear circuit analysis based on elementary aspects of projective geometry. We use a flexible approach in which no a priori assignment of an electrical nature to the circuit branches is necessary. Such an assignment is eventually done just by setting certain model parameters, in a way which avoids the need ...
openaire   +3 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Multi-person feature fusion transfer learning-based convolutional neural network for SSVEP-based collaborative BCI

Frontiers in Neuroscience, 2022
ObjectiveThe conventional single-person brain–computer interface (BCI) systems have some intrinsic deficiencies such as low signal-to-noise ratio, distinct individual differences, and volatile experimental effect.
Penghai Li, Jianxian Su, Abdelkader Nasreddine Belkacem, Longlong Cheng, Chao Chen   +4 more
doaj   +1 more source

Circuit Theory for Full Counting Statistics in Multiterminal Circuits

Physical Review Letters, 2002
We propose a theory that treats the current, noise, and, generally, the full current statistics of electron transfer in a mesoscopic system in a unified, simple and efficient way. The theory appears to be a circuit theory of $2\times 2$ matrices associated with Keldysh Green functions.
Nazarov, Yu.V. (author), Bagrets, D.A. (author)   +1 more
openaire   +5 more sources

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Energy-Efficient Aggressive Duty-Cycling of V-Band Power Amplifiers

IEEE Access
In addition to implementing the core functionality, a design goal for modern circuits is reduced energy consumption. When options for improving active state efficiency are eventually exhausted, the next step is to aggressively minimize the duration a ...
Maximilian Gottfried Becker, Marco Gunia, Diego Mendez, Frank Ellinger   +3 more
doaj   +1 more source