Results 61 to 70 of about 823,290 (291)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Designing a Power and Speed Adaptive 60 GHz Receiver in 22 nm FD-SOI CMOS for Tactile Internet Applications

IEEE Access
This research presents and examines the first power and speed adaptive 60 GHz receiver, combining the potential of high data rates with low energy consumption.
Helmuth P. E. Morath, Xin An, Matthias Jobst, Mengqi Cui, Jens Wagner, Christian Mayr, Frank Ellinger   +6 more
doaj   +1 more source

Efficiency of Innovative Charge Pump versus Clock Frequency and MOSFETs Sizes

Measurement Science Review, 2016
Charge pumps are circuits that produce the voltage higher than supply voltage or negative voltage. Today, charge pumps became an integral part of the electronic equipment.
Matoušek David, Hospodka Jiří, Šubrt Ondřej   +2 more
doaj   +1 more source

Asymmetry and decoherence in a double-layer persistent-current qubit

, 2005
Superconducting circuits fabricated using the widely used shadow evaporation technique can contain unintended junctions which change their quantum dynamics.
A. O. Caldeira, C. H. van der Wal, David P. DiVincenzo, Guido Burkard, I. Chiorescu, J. E. Mooij, L. Tian, M. H. Devoret, P. Bertet   +8 more
core   +2 more sources

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Early thrombus detection in ECMO with optimized impedance measurements: A simulative study

Journal of Electrical Bioimpedance
Extracorporeal oxygenation supports patients with severe cardiac or respiratory failure, with the oxygenator providing critical gas exchange. Thrombus formation in the oxygenator can impair efficiency and increase risks such as hemolysis and embolism ...
Slapal Filip, Silva Diogo F., Leonhardt Steffen, Walter Marian   +3 more
doaj   +1 more source

Full counting statistics of Andreev scattering in an asymmetric chaotic cavity

, 2005
We study the charge transport statistics in coherent two-terminal double junctions within the framework of the circuit theory of mesoscopic transport.
A. F. Andreev, A. F. Andreev, C. W. J. Beenakker, L. S. Levitov, M. J. M. de Jong, Mihajlo Vanević, O. M. Bulashenko, S. Oberholzer, V. A. Khlus, V. A. Khlus, Wolfgang Belzig, Yu. V. Nazarov, Yu. V. Nazarov   +12 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

A 60 GHz Broadband LNA With Joined Variable Gain Control and Switching in 22 nm FD-SOI

IEEE Access
This paper investigates a 60 GHz low-power broadband low noise amplifier (LNA) with variable gain control. To prove the concept, the circuit is implemented in a 22nm fully depleted silicon on insulator (FD-SOI) CMOS technology.
Xin Xu, Jens Wagner, Corrado Carta, Frank Ellinger   +3 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source