Results 71 to 80 of about 467,200 (296)

Minimal velocity surface in the restricted circular Three-Body-Problem

Vestnik of Saint Petersburg University. Mathematics. Mechanics. Astronomy, 2020
In the framework of the restricted circular Three-Body-Problem, the concept of the minimum velocity surface S is introduced, which is a modification of the zero-velocity surface (Hill surface). The existence of Hill surface requires occurrence of the Jacobi integral. The minimum velocity surface, other than the Jacobi integral, requires conservation of
K. V. Kholshevnikov, V. B. Titov
openaire   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Construction of Analytical Eigensolutions for Isotropic Conical Bodies and Their Application for Estimation of Stresses Singularity

Fracture and Structural Integrity, 2019
A complete set of eigensolutions is constructed for different variants of circular conical bodies: homogeneous cone with one lateral surface (solid cone), homogeneous cone with two lateral surfaces (hollow cone) and composite cone for different variants ...
Tatyana Korepanova, Valerii Matveenko, Igor Shardakov   +2 more
doaj   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A substitute for the singular Green kernel in the Newtonian potential of celestial bodies [PDF]

, 2012
The "point mass singularity" inherent in Newton's law for gravitation represents a major difficulty in accurately determining the potential and forces inside continuous bodies.
A. Dieckmann, Adams, Ansorg, Baruteau, Clement, Cohl, Dermott, El-Zant, Grandclément, Hachisu, Hachisu, Huré, Huré, J.-M. Huré, Romeo, Schulz, Sommer-Larsen, Stemwedel, Stone   +18 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

First Law of Mechanics for Black Hole Binaries with Spins

, 2013
We use the canonical Hamiltonian formalism to generalize to spinning point particles the first law of mechanics established for binary systems of non-spinning point masses moving on circular orbits [Le Tiec, Blanchet, and Whiting, Phys. Rev. D 85, 064039
Blanchet, Luc, Buonanno, Alessandra, Tiec, Alexandre Le   +2 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On the restricted circular three-charged-body problem

Astrophysics and Space Science, 1987
Three bodies \(M_ 1\), \(M_ 2\) and M with masses \(m_ 1\), \(m_ 2\) and \(m=0\), and charges \(q_ 1\), \(q_ 2\), \(q=0\) revolve around the centre of mass of the first two in circular orbits attracting (or repulsing) each other according to the Newtonian and Coulombian inverse square law.
Dionysiou, D.D., Vaiopoulos, D.A.
openaire   +2 more sources