Results 51 to 60 of about 2,008,153 (347)
Hepatology, 2017 Noncoding RNAs play important roles in cancer biology, providing potential targets for cancer intervention. As a new class of endogenous noncoding RNAs, circular RNAs (circRNAs) have been recently identified in cell development and function, and certain ...
Dan Han +13 more
semanticscholar +1 more source
Cell Transplantation, 2019 Emerging evidence demonstrates that dysregulation of circular RNA is linked to tumorigenesis and aggressive progression. However, its role in oral squamous cell carcinoma remains largely uncharacterized.
Bing Xia +4 more
doaj +1 more source
Circular RNA Regulation of Myogenesis
Cells, 2019 Circular RNA (circRNA) is a novel class of non-coding RNA generated by pre-mRNA back splicing, which is characterized by a closed-loop structure. Although circRNAs were firstly reported decades ago, their regulatory roles have not been discovered until ...
Pengpeng Zhang +10 more
doaj +1 more source
Cost-Effective Transcriptome-Wide Profiling of Circular RNAs by the Improved-tdMDA-NGS Method
Frontiers in Molecular Biosciences, 2022 Covalently closed circular RNAs are neoteric to the eukaryotic family of long non-coding RNAs emerging as a result of 5′–3′ backsplicing from exonic, intronic, or intergenic regions spanning the parental gene.
Ashirbad Guria +5 more
doaj +1 more source
Complete genome sequence of Thermaerobacter marianensis type strain (7p75a). [PDF]
, 2010 Thermaerobacter marianensis Takai et al. 1999 is the type species of the genus Thermaerobacter, which belongs to the Clostridiales family Incertae Sedis XVII. The species is of special interest because T.
Bristow, James +35 more
core +1 more source
Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis
Journal of the National Cancer Institute, 2017 Background Circular RNAs (circRNAs) are RNA transcripts that are widespread in the eukaryotic genome. Recent evidence indicates that circRNAs play important roles in tissue development, gene regulation, and carcinogenesis.
Yibing Yang +12 more
semanticscholar +1 more source
Thermodynamic Analysis of Interacting Nucleic Acid Strands [PDF]
, 2007 Motivated by the analysis of natural and engineered DNA and RNA systems, we present the first algorithm for calculating the partition function of an unpseudoknotted complex of multiple interacting nucleic acid strands.
Bois, Justin S. +4 more
core +3 more sources
CIRI: an efficient and unbiased algorithm for de novo circular RNA identification
Genome Biology, 2015 Recent studies reveal that circular RNAs (circRNAs) are a novel class of abundant, stable and ubiquitous noncoding RNA molecules in animals. Comprehensive detection of circRNAs from high-throughput transcriptome data is an initial and crucial step to ...
Yuan Gao, Jinfeng Wang, F. Zhao
semanticscholar +1 more source
Synthetic circular RNA switches and circuits that control protein expression in mammalian cells
Nucleic Acids Research, 2023 Synthetic messenger RNA (mRNA) has been focused on as an emerging application for mRNA-based therapies and vaccinations. Recently, synthetic circular RNAs (circRNAs) have shown promise as a new class of synthetic mRNA that enables superior stability and ...
Shigetoshi Kameda +2 more
semanticscholar +1 more source
Advances in Circular RNA and Its Applications
International Journal of Medical Sciences, 2022 Circular RNA (circRNA) is a novel endogenous non-coding RNA (ncRNA) that, like microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, unlike traditional linear RNAs (which have 5' and 3' ends), has a closed-loop structure that is unaffected
Xian-guo Zhao +4 more
semanticscholar +1 more source