Results 41 to 50 of about 28,809 (247)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Manufacturers’ adoption of circularity science in supply chains and its perceived viability to promote sustainable performance: Qualitative-empirical evidence from Kenya

Sustainable Environment
Objective: This paper serves a triadic purpose: To investigate manufacturers’ adoption of circularity science in supply chains and its perceived viability to promote sustainable performance through assessing supply chain anthropogenic practices ...
Mary Aming’a, Jonathan Annan, Reuben Marwanga   +2 more
doaj   +1 more source

Definitions of the circular economy: Circularity matters

Ecological Economics, 2023
With more than 4,000 research articles in 2022 the Circular Economy is clearly a topic that meets academic interest. With resource use at an all-time, unsustainable peak it is also a topic that raises great expectations: We need the circular economy. The great hopes that we all have are further fueled by the definitions of the circular economy that we ...
Figge, Frank, Thorpe, Andrea, Gutberlet, Melissa   +2 more
openaire   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Food Security and Circular Cities: Paradigmatic Shifts, Geographical and Temporal Scales, and Participatory Governance Support to Facilitate Transitions Towards ‘Urban Sustainability’

Urban Science
This article explores how the principles of circularity, applied to urban food systems, could contribute to catalysing a transition towards more sustainable cities, working on the premise that food security is a key pillar of urban resilience.
Sandrine Simon
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Circular Knowledge – Circular Craft

, 2022
L'intervento fa il punto su cosa voglia dire fare artigianato oggi all'interno dei parametri della sviluppo sostenibile e dell'economia circolare. Si presenta poi l'esperienza dell'allestimento di una Mostra sul tema.
Giuseppe Lotti, Eleonora Trivellin
openaire   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Interim tandems of life cycle assessment methods and circularity indicators—elaboration for the circular bio-economy

Frontiers in Sustainability
IntroductionThe transition toward a circular economy (CE) is a key strategy for sustainable production and consumption, yet its contribution to sustainability depends on how it is assessed.
Dieuwertje Schrijvers, Thomas Schaubroeck, Margarida Vidinha, Michael Saidani, Michael Saidani, Alexandre Charpentier Poncelet, Milena Amaral, Eduardo Entrena Barbero, María Gallego Fernández, Tomas Rydberg, Naeem Adibi   +10 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source